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Autophagy and Alzheimer’s Disease

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Autophagy: Biology and Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1207))

Abstract

Alzheimer’s disease (AD) is the most common type of dementia and is characterized by progressive cognitive decline. Increasing evidence has demonstrated that the autophagic process plays an important role in AD. In this chapter, we will discuss the role of autophagy in the pathogenesis of AD and other types of dementia, including dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), vascular dementia (VD) and prion diseases. In addition, we will discuss autophagy-targeted therapies as future treatments for AD.

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Correspondence to Weidong Le .

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Chen, S., Zhou, Q., Ni, Y., Le, W. (2020). Autophagy and Alzheimer’s Disease. In: Le, W. (eds) Autophagy: Biology and Diseases. Advances in Experimental Medicine and Biology, vol 1207. Springer, Singapore. https://doi.org/10.1007/978-981-15-4272-5_1

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