Skip to main content

Dimensions of Personality and Neuropsychological Function in Eating Disorders, Substance Use Disorders, and Addictions

  • Chapter
  • First Online:
Eating Disorders, Addictions and Substance Use Disorders

Abstract

Substance abuse, eating disorders, and other addictive behavior problems tend to be comorbid with personality disorders and with dimensions of personality pathology. Substance abuse and pathological gambling tend to be highly comorbid with antisocial personality disorder, whereas eating disorders are often comorbid with both Cluster B and Cluster C personality disorders. These comorbidities can increase symptom severity and compromise treatment. Negative emotionality, negative urgency, and sensation seeking correlate with most forms of addictive behavior, although anorexia nervosa appears quite different and is associated with lower levels of novelty seeking and high levels of self-directedness and perfectionism. Well-developed neurobiological models of brain system functioning and neurotransmitter plasticity paint a picture of how the initially impulsive engagement in addictive behaviors can become compulsive over time. Behavioral and pharmacological treatment strategies emphasize renewed engagement in nondrug pleasurable activities, and new treatments are being developed that target the specific personality pathology of the patient.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
eBook
USD 129.00
Price excludes VAT (USA)
Softcover Book
USD 169.99
Price excludes VAT (USA)
Hardcover Book
USD 249.99
Price excludes VAT (USA)

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders—Text revised (5th ed.). Arlington, VA: American Psychiatric Publishing.

    Google Scholar 

  • Anderluh, M. B., Tchanturia, K., Rabe-Hesketh, S., & Treasure, J. (2003). Childhood obsessive-compulsive personality traits in adult women with eating disorders: Defining a broader eating disorder phenotype. American Journal of Psychiatry, 160, 242–247.

    Article  PubMed  Google Scholar 

  • Barbas, H. (2007). Specialized elements of orbitofrontal cortex in primates. Linking Affect to Action: Critical Contributions of the Orbitofrontal Cortex, 1121, 10–32.

    Google Scholar 

  • Bechara, A., Damasio, A., Damasio, H., & Anderson, S. W. (1994). Insensitivity to future consequences following damage to human prefrontal cortex. Cognition, 50, 7–15.

    Article  CAS  PubMed  Google Scholar 

  • Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (2007). Deciding advantageously before knowing the advantageous strategy. Science, 275, 1293–1295.

    Article  Google Scholar 

  • Bechara, A., Tranel, D., & Damasio, H. (2000). Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions. Brain, 123, 2189–2202.

    Article  PubMed  Google Scholar 

  • Blaszczynski, A. P., & McConaghy, N. (1994). Antisocial personality disorder and pathological gambling. Journal of Gambling Studies, 10, 129–145.

    Article  CAS  PubMed  Google Scholar 

  • Blaszczynski, A., & Steel, Z. (1998). Personality disorders among pathological gamblers. Journal of Gambling Studies, 14, 51–71.

    Article  PubMed  Google Scholar 

  • Brewerton, T. D. (1995). Toward a unified theory of serotonin dysregulation in eating and related disorders. Psychoneuroendocrinology, 20, 561–590.

    Article  CAS  PubMed  Google Scholar 

  • Brewerton, T. D., Mueller, E. A., Lesem, M. D., Brandt, H. A., Quearry, B., George, D., …, Jimerson, D. C. (1992). Neuroendocrine responses to m-chlorophenylpiperazine and L-tryptophan in bulimia. Archives of General Psychiatry, 49, 852–861.

    Google Scholar 

  • Broft, A., Shingleton, R., Kaufman, J., Liu, F., Kumar, D., Slifstein, M., …, Walsh, B. (2012). Striatal dopamine in bulimia nervosa: A PET imaging study. International Journal of Eating Disorders, 45, 648–656.

    Google Scholar 

  • Bruce, K. R., & Steiger, H. (2005). Treatment implications of Axis-II comorbidity in eating disorders. Eating Disorders, 13, 93–108.

    Article  PubMed  Google Scholar 

  • Cardinal, R. N., Parkinson, J. A., Hall, J., & Everitt, B. J. (2002). Emotion and motivation: The role of the amygdale, ventral striatum, and prefrontal cortex. Neuroscience and Biobehavioral Reviews, 26, 321–352.

    Article  PubMed  Google Scholar 

  • Cassin, S. E., & von Ranson, K. M. (2005). Personality and eating disorders: A decade in review. Clinical Psychology Review, 25, 895–916.

    Article  PubMed  Google Scholar 

  • Compton, W. M., Conway, K. P., Stinson, F. S., Colliver, J. D., & Grant, B. F. (2005). Prevalence, correlates, and comorbidity of DSM-IV antisocial personality syndromes and alcohol and specific drug use disorders in the United States: Results from the National Epidemiological Survey on alcohol and related conditions. Journal of Clinical Psychiatry, 66, 677–685.

    Article  PubMed  Google Scholar 

  • Cools, R., Blackwell, A., Clark, L., Menzies, L., Cox, S., & Robbins, T. W. (2005). Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity. Neuropsychopharmacology, 30, 1362–1373.

    CAS  PubMed  Google Scholar 

  • Cyders, M. A., Flory, K., Rainer, S., & Smith, G. T. (2009). Prospective study of the integration of mood and impulsivity to predict increases in maladaptive action during the first year of college. Addiction, 104, 193–202.

    Article  PubMed  PubMed Central  Google Scholar 

  • Cyders, M. A., & Smith, G. T. (2008a). Emotion-based dispositions to rash action: Positive and negative urgency. Psychological Bulletin, 6, 807–828.

    Article  Google Scholar 

  • Cyders, M. A., & Smith, G. T. (2008b). Clarifying the role of personality dispositions in risk for increased gambling behavior. Personality and Individual Differences, 45, 503–508.

    Article  PubMed  PubMed Central  Google Scholar 

  • Depue, R. A. (1995). Neurobiological factors in personality and depression. European Journal of Personality, 9, 413–439.

    Article  Google Scholar 

  • Depue, R. A., & Collins, P. F. (1999). Neurobiology of the structure of personality: DA, facilitation of incentive motivation, and extraversion. Behavioral and Brain Sciences, 22, 491–569.

    CAS  PubMed  Google Scholar 

  • Dimidjian, S., Hollon, S. D., Dobson, K. S., Schmaling, K. B., Kohlenberg, R. J., Addis, M. E., …, Jacobson, N. S. (2006). Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. Journal of Consulting and Clinical Psychology, 74, 658–670.

    Google Scholar 

  • Duggan, C., Mason, L., Banerjee, P., & Milton, J. (2007). Value of standard personality assessments in informing clinical decision – making in a medium secure unit. British Journal of Psychiatry Supplements, 49, s15–s19.

    Article  Google Scholar 

  • Engel, S. G., Corneliussen, S. J., Wonderlich, S. A., Crosby, R. D., le Grange, D., Crow, S., …, Steiger, H. (2005). Impulsivity and compulsivity in bulimia nervosa. International Journal of Eating Disorders, 38, 244–251.

    Google Scholar 

  • Fassino, S., Svrakic, D., Abbate-Daga, G., Leombruni, P., Amianto, F., Stanic, S., & Rovera, G. (2002). Anorectic family dynamics: Temperament and character data. Comprehensive Psychiatry, 43, 114–120.

    Google Scholar 

  • Fischer, S., Smith, G. T., & Cyders, M. A. (2008). Another look at impulsivity: A meta-analytic review comparing specific dispositions to rash action in their relationship to bulimic symptoms. Clinical Psychology Review, 28, 1413–1425.

    Article  PubMed  PubMed Central  Google Scholar 

  • Floresco, S. B., & Tse, M. (2007). Dopaminergic regulation of inhibitory and excitatory transmission in the basolateral amygdala-prefrontal cortical pathway. The Journal of Neuroscience, 27, 2045–2057.

    Article  CAS  PubMed  Google Scholar 

  • Frankle, W., Lombardo, I., New, A. S., Goodman, M., Talbot, P. S., Huang, Y., …, Siever, L. J. (2005). Brain 5HT transporter distribution in subjects with impulsive aggressivity: A positron emission study with 1CMcN5652. American Journal of Psychiatry, 162, 915–923.

    Google Scholar 

  • Friedel, R. O. (2004). DA dysfunction in borderline personality disorder: A hypothesis. Neuropsychopharmacology, 29, 1029–1039.

    Article  CAS  PubMed  Google Scholar 

  • Ghashghaei, H. T., & Barbas, H. (2002). Pathways for emotion: Interactions of prefrontal and anterior temporal pathways in the amygdala of the rhesus monkey. Neuroscience, 115, 1261–1279.

    Article  CAS  PubMed  Google Scholar 

  • Goldbloom, D. S., Garfinkle, P. E., Katz, R., & Brown, G. (1990). The hormonal response to intravenous 5-hydroxytryptophan in bulimia nervosa. Psychosomatic Medicine, 52, 225–226.

    Google Scholar 

  • Grilo, C. M., Sanislow, C. A., Shea, M., Skodol, A. E., Stout, R. L., Pagano, M. E., …, McGlashan, T. H. (2003). Natural course of bulimia nervosa and eating disorders not otherwise specified is not influenced by personality disorders. International Journal of Eating Disorders, 24, 319–330.

    Google Scholar 

  • Grunwald, M., Ettrich, C., Busse, F., Assmann, B., Dähne, A., & Gertz, H. (2002). Angle paradigm: A new method to measure right parietal dysfunctions in anorexia nervosa. Archives of Clinical Neuropsychology, 17, 485–496.

    Article  PubMed  Google Scholar 

  • Halmi, K. A., Tozzi, F., Thornton, L. M., Crow, S., Fichter, M. M., Kaplan, A. S., …, Bulik, C. M. (2005). The relation among perfectionism, obsessive-compulsive personality disorder and obsessive-compulsive disorder in individuals with eating disorders. International Journal of Eating Disorders, 38, 371–374.

    Google Scholar 

  • Jarry, J. L., & Vaccarino, F. J. (1996). Eating disorder and obsessive-compulsive disorder: Neurochemical and phenomenological commonalities. Journal of Psychiatry and Neuroscience, 21, 36–48.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Jimerson, D. C., Lesem, M. D., Kaye, W. H., & Brewerton, T. D. (1992). Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes. Archives of General Psychiatry, 49, 132–138.

    Article  CAS  PubMed  Google Scholar 

  • Johnson, C., Tobin, D. L., & Dennis, A. (1990). Differences in treatment outcome between borderline and nonborderline bulimics at one-year follow-up. International Journal of Eating Disorders, 9, 617–627.

    Article  Google Scholar 

  • Johnson, C., Tobin, D., & Enright, A. (1989). Prevalence and clinical characteristics of borderline patients in an eating-disordered population. Journal of Clinical Psychiatry, 50, 9–15.

    CAS  PubMed  Google Scholar 

  • Kaye, W. H., Greeno, C. G., Moss, H., Fernstrom, J., Fernstrom, M., Lilenfeld, L. R., … & Mann, J. (1998). Alterations in serotonin activity and psychiatric symptoms after recovery from bulimia nervosa. Archives of General Psychiatry, 55, 927–935.

    Google Scholar 

  • Kaye, W. H., Gwirtsman, H. E., George, D. T., & Ebert, M. H. (1991). Altered serotonin activity in anorexia nervosa after long-term weight restoration: Does elevated cerebrospinal fluid 5-hydroxyindoleacetic acid level correlate with rigid and obsessive behavior? Archives of General Psychiatry, 48, 556–562.

    Article  CAS  PubMed  Google Scholar 

  • Klump, K. L., Bulik, C. M., Pollice, C., Halmi, K. A., Fichter, M. M., Berrettini, W. H., …, Kaye, W. H. (2000). Temperament and character in women with anorexia nervosa. The Journal of Nervous and Mental Disease, 188, 559–567.

    Google Scholar 

  • Koob, G. F., & Le Moal, M. (2005). Plasticity of reward neurocircuitry and the ‘dark side’ of drug addiction. Nature Neuroscience, 8, 1442–1444.

    Article  CAS  PubMed  Google Scholar 

  • Koob, G. F., & Volkow, N. D. (2010). Neurocircuitry of addiction. Neuropsychopharmacology Reviews, 35, 217–238.

    Article  PubMed  PubMed Central  Google Scholar 

  • Krakowski, M. (2003). Violence and 5HT: Influence of impulse control, affect regulation, and social functioning. Journal of Neuropsychiatry and Clinical Neurosciences, 15, 294–305.

    Article  CAS  PubMed  Google Scholar 

  • Law, S. (2013). Relationship between problem gambling and psychiatric disorders. Retrieved from http://www.problemgambling.ca/en/resourcesforprofessionals/pages/relationshipbetween-problemgamblingandpsychiatricdisorders.aspx

  • LeDoux, J. E. (2000). Emotion circuits in the brain. Annual Review of Neuroscience, 23, 155–184.

    Article  CAS  PubMed  Google Scholar 

  • Lewis, M. D., & Todd, R. M. (2007). The self-regulating brain: Cortical-subcortical feedback and the development of intelligent action. Cognitive Development, 22, 406–430.

    Article  Google Scholar 

  • Lilenfeld, L. R. R., Wonderlich, S., Riso, L. P., Crosby, R., & Mitchell, J. (2006). Eating disorders and personality: A methodological and empirical review. Clinical Psychology Review, 26, 299–320.

    Article  PubMed  Google Scholar 

  • Linehan, M. M. (1993). Cognitive behavioral treatment of borderline personality disorder. New York, NY: Guilford Press.

    Google Scholar 

  • Martin-Solch, C., Magyar, S., Kunig, G., Missimer, J., Schultz, W., & Leenders, K. L. (2001). Changes in brain activation associated with reward processing in smokers and nonsmokers: A positron emission tomography study. Experimental Brain Research, 139, 278–286.

    Article  CAS  PubMed  Google Scholar 

  • McGue, M., Slutske, W., & Iacono, W. G. (1999). Personality and substance use disorders: II. Alcoholism versus drug use disorders. Journal of Consulting and Clinical Psychology, 67, 394–404.

    Article  CAS  PubMed  Google Scholar 

  • McGue, M., Slutske, W., Taylor, J., & Iacono, W. G. (1997). Personality and substance use disorders: I. effects of gender and alcoholism subtype. Alcoholism, Clinical and Experimental Research, 21, 513–520.

    CAS  PubMed  Google Scholar 

  • Meyers, R. J., & Miller, W. R. (Eds.). (2006). A community reinforcement approach to addiction treatment. Cambridge: Cambridge University Press.

    Google Scholar 

  • Miller, W. R., & Rollnick, S. (2002). Motivational interviewing: Preparing people for change (2nd ed.). New York, NY: Guilford Press.

    Google Scholar 

  • Morelli, E., Moore, H., Rebello, T. J., Gray, N., Steele, K., Esposito, E., …, Ansorge, M. S. (2011). Chronic 5-HT transporter blockade reduces DA signaling to elicit basal ganglia dysfunction. The Journal of Neuroscience, 31, 15742–15750.

    Google Scholar 

  • Morgan, M. J., Impallomeni, L. C., Pironi, A., & Rogers, R. D. (2006). Elevated impulsivity and impaired decision-making in abstinent ecstasy (MDMA) users compared to polydrug and drug-naïve controls. Neuropsychopharmacology, 31, 1562–1573.

    Article  CAS  PubMed  Google Scholar 

  • Nico, D. D., Daprati, E. E., Nighoghossian, N. N., Carrier, E. E., Duhamel, J. R., & Sirigu, A. A. (2010). The role of the right parietal lobe in anorexia nervosa. Psychological Medicine, 40, 1531–1539.

    Article  CAS  PubMed  Google Scholar 

  • Pearson, C. M., Combs, J. L., Zapolski, T. C. B., & Smith, G. T. (2012). A longitudinal transactional risk model for early eating disorder onset. Journal of Abnormal Psychology, 121, 707–718.

    Article  PubMed  Google Scholar 

  • Pearson, C. M., Guller, L., Spillane, N. S., & Smith, G. T. (2011). A developmental model of addictive behavior: From impulsivity to compulsivity. In A. M. Columbus (Ed.), Advances in psychology research (Vol. 77). New York, NY: Nova.

    Google Scholar 

  • Pietrzak, R., & Petry, N. M. (2005). Antisocial personality disorder is associated with increased severity of gambling, medical, drug and psychiatric problems among treatment-seeking pathological gamblers. Addiction, 100, 1183–1193.

    Article  PubMed  Google Scholar 

  • Potenza, M. N. (2008). The neurobiology of pathological gambling and drug addiction: An overview and new findings. Philosophical Transactions of the Royal Society, 363, 3181–3189.

    Article  Google Scholar 

  • Potenza, M. N., Sofuoglu, M., Carroll, K. M., & Rounsaville, B. J. (2011). Neuroscience of behavioral and pharmacological treatments for addictions. Neuron, 69, 695–712.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rossier, V., Bolognini, M., Plancherel, B., & Halfon, O. (2000). Sensation seeking: A personality trait characteristic of adolescent girls and young women with eating disorders. European Eating Disorders Review, 8, 245–252.

    Article  Google Scholar 

  • Rothman, R. B., Blough, B. E., & Baumann, M. H. (2008). Dual dopamine/serotonin releasers: Potential treatment agents for stimulant addiction. Experimental and Clinical Psychopharmacology, 16, 458–474.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Safer, D. L., Robinson, A. H., & Jo, R. (2010). Outcome from a randomized controlled trial of group therapy for binge eating disorder: Comparing dialectical behavior therapy adapted for binge eating to an active comparison group therapy. Behavior Therapy, 41, 106–120.

    Article  PubMed  PubMed Central  Google Scholar 

  • Safer, D. L., Telch, C. F., & Agras, W. S. (2001). Dialectical behavioral therapy for bulimia nervosa. American Journal of Psychiatry, 158, 632–634.

    Article  CAS  PubMed  Google Scholar 

  • Salekin, R. T. (2002). Psychopathy and therapeutic pessimism: Clinical lore or clinical reality? Clinical Psychology Review, 22, 79–112.

    Article  PubMed  Google Scholar 

  • Settles, R. F., Cyders, M., & Smith, G. T. (2010). Longitudinal validation of the acquired preparedness model of drinking risk. Psychology of Addictive Behaviors, 24, 198–208.

    Article  PubMed  PubMed Central  Google Scholar 

  • Sher, K. J., Bartholow, B. D., & Wood, M. D. (2000). Personality and substance use disorders: A prospective study. Journal of Consulting and Clinical Psychology, 68, 818–829.

    Article  CAS  PubMed  Google Scholar 

  • Skodol, A. E., & Oldham, J. M. (1996). Phenomenology, differential diagnosis, and comorbidity of the impulsive-compulsive spectrum of disorders. In J. M. Oldham, E. Hollander, & A. E. Skodol (Eds.), Impulsivity and compulsivity (pp. 1–36). Arlington, VA: American Psychiatric Association.

    Google Scholar 

  • Slutske, W. S., Caspi, A., Moffitt, T. E., & Poulton, R. (2005). Personality and problem gambling. Archives of General Psychiatry, 62, 769–775.

    Article  PubMed  Google Scholar 

  • Slutske, W. S., Eisen, S., Xian, H., True, W. R., Lyons, M. J., Goldberg, M., & Tsuang, M. (2001). A twin study of the association between pathological gambling and antisocial personality disorder. Journal of Abnormal Psychology, 110, 297–308.

    Google Scholar 

  • Smyth, J. M., Wonderlich, S. A., Heron, K. E., Sliwinski, M. J., Crosby, R. D., Mitchell, J. E., & Engel, S. G. (2007). Daily and momentary mood and stress are associated with binge eating and vomiting in bulimia nervosa patients in the natural environment. Journal of Consulting and Clinical Psychology, 75, 629–638.

    Google Scholar 

  • Spear, L. P. (2000). The adolescent brain and age related behavioral manifestations. Neuroscience and Behavioral Reviews, 24, 417–463.

    Article  CAS  Google Scholar 

  • Spoont, M. R. (1992). Modulatory role of serotonin in neural information processing: Implications for human psychopathology. Psychological Bulletin, 112, 330–350.

    Article  CAS  PubMed  Google Scholar 

  • Steiger, H., & Bruce, K. R. (2007). Phenotypes, endophenotypes, and genotypes in bulimia spectrum eating disorders. Canadian Journal of Psychiatry, 52, 220–227.

    Google Scholar 

  • Steiger, H., Israel, M., Gauvin, L., Kin, N. Y., & Young, S. N. (2003). Implications of compulsive and impulsive traits for serotonin status in women with bulimia nervosa. Psychiatry Research, 120, 219–229.

    Article  CAS  PubMed  Google Scholar 

  • Steiger, H., Jabalpurwala, S., Champagne, J., & Stotland, S. (1997). A controlled study of trait narcissism in anorexia and bulimia nervosa. International Journal of Eating Disorders, 22, 173–178.

    Article  CAS  PubMed  Google Scholar 

  • Stephenson, M. T. (2003). Mass media strategies targeting high sensation seekers: What works and why. American Journal of Health Behavior, 27(Suppl 3), S233–S238.

    Article  PubMed  Google Scholar 

  • Stice, E. (2002). Risk and maintenance factors for eating pathology: A meta-analytic review. Psychological Bulletin, 128, 825–848.

    Article  PubMed  Google Scholar 

  • Telch, C. F., Agras, W. S., & Linehan, M. M. (2001). Dialectical behavior therapy for binge eating disorder. Journal of Consulting and Clinical Psychology, 69, 1061–1065.

    Article  CAS  PubMed  Google Scholar 

  • Vitousek, K. M., & Manke, F. (1994). Personality variables and disorders in anorexia nervosa and bulimia nervosa. Journal of Abnormal Psychology, 103, 137–147.

    Article  CAS  PubMed  Google Scholar 

  • Volkow, N. D., & Fowler, J. S. (2000). Addiction, a disease of compulsion and drive: Involvement of the orbitofrontal cortex. Cerebral Cortex, 10, 318–325.

    Article  CAS  PubMed  Google Scholar 

  • Volkow, N. D., Fowler, J. S., Wang, G. J., & Swanson, J. M. (2004). Dopamine in drug abuse and addiction: Results from imaging studies and treatment implications. Molecular Psychiatry, 9, 557–569.

    Article  CAS  PubMed  Google Scholar 

  • Volkow, N. D., & Wang, G. J. (1996). Relationship between psychostimulant-induced ‘high’ and dopamine transporter occupancy. Proceedings of the National Academy of Sciences of the United States of America, 93, 10388–10392.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Volkow, N. D., Wang, G. J., Fowler, J. S., Logan, J., Jayne, M., Franceschi, D., …, Pappas, N. (2002). “Nonhedonic” food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse, 44, 175–180.

    Google Scholar 

  • Volkow, N. D., Wang, G., Fowler, J. S., Tomasi, D., Telang, F., & Baler, R. (2010). Addiction: Decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain’s control circuit. Bioessays, 32, 748–755.

    Article  PubMed  PubMed Central  Google Scholar 

  • Volkow, N. D., Wang, G., Maynard, L., Jayne, M., Fowler, J. S., Wei, Z., …, Pappas, N. (2003). Brain dopamine is associated with eating behaviors in humans. International Journal of Eating Disorders, 33, 136–142.

    Google Scholar 

  • Westermeyer, J., & Thuras, P. (2005). Association of antisocial personality disorder and substance disorder morbidity in a clinical sample. The American Journal of Drug and Alcohol Abuse, 1, 93–110.

    Article  Google Scholar 

  • Wilfley, D. E., Friedman, M. A., Dounchis, J. Z., Stein, R. I., Welch, R. R., & Ball, S. A. (2000). Comorbid psychopathology in binge eating disorder: Relation to eating disorder severity at baseline and following treatment. Journal of Consulting and Clinical Psychology, 68, 641–649.

    Article  CAS  PubMed  Google Scholar 

  • Winstanley, C. A., Dalley, J. W., Theobald, D. E. H., & Robbins, T. W. (2004). Fractionating impulsivity: Contrasting effects of central 5-HT depletion on different measures of impulsive behavior. Neuropsychopharmacology, 29, 1331–1343.

    Article  CAS  PubMed  Google Scholar 

  • Winstanley, C. A., Eagle, D. M., & Robbins, T. W. (2006). Behavioral models of impulsivity in relation to ADHD: Translation between clinical and preclinical studies. Clinical Psychology Review, 26, 379–395.

    Article  PubMed  PubMed Central  Google Scholar 

  • Winstanley, C. A., Theobald, D. E. H., Dalley, J. W., Glennon, J. C., & Robbins, T. W. (2004). 5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: Interactions with global 5-HT depletion. Psychopharmacology, 176, 376–385.

    Article  CAS  PubMed  Google Scholar 

  • Wonderlich, S. A., Crosby, R. D., Engel, S. G., Mitchell, J. E., Smyth, J., & Miltenberger, R. (2007). Personality-based clusters in bulimia nervosa: Differences in clinical variables and ecological momentary assessment. Journal of Personality Disorders, 21, 340–357.

    Article  PubMed  Google Scholar 

  • Wonderlich, S. A., Engel, S. G., Peterson, C. B., Robinson, M. D., Crosby, R. D., Mitchell, J. E., …, Simonich, H. K. (2008). Examining the conceptual model of integrative cognitive-affective therapy for BN: Two assessment studies. International Journal of Eating Disorders, 41, 748–754.

    Google Scholar 

  • Wonderlich, S. A., & Mitchell, J. E. (1997). Eating disorders and comorbidity: Empirical, conceptual, and clinical implications. Psychopharmacology Bulletin, 33, 381–390.

    CAS  PubMed  Google Scholar 

  • Wonderlich, S. A., & Mitchell, J. E. (2001). The role of personality in the onset of eating disorders and implications for treatment. The Psychiatric Clinics of North America, 24, 249–258.

    Article  CAS  PubMed  Google Scholar 

  • Wonderlich, S. A., Peterson, C. B., Crosby, R. D., Smith, T. L., Klein, M. H., Mitchell, J. E., et al. (2014). A randomized controlled comparison of integrative cognitive-affective therapy (ICAT) and enhanced cognitive-behavioral therapy (CBT-E) for bulimia nervosa. Psychological Medicine, 44, 543–553

    Google Scholar 

  • Wonderlich, S., Peterson, C. B., Smith, T. L., Klein, M., Mitchell, J. E., Crow, S., et al. (2010). Integrative cognitive-affective therapy for the treatment of bulimia nervosa. In C. M. Grilo & J. E. Mitchell (Eds.), The treatment of eating disorders: A clinical handbook (pp. 317–338). New York, NY: Guilford Press

    Google Scholar 

  • Zack, M., & Poulos, C. X. (2009). Parallel roles for dopamine in pathological gambling and psychostimulant addiction. Current Drug Abuse Reviews, 2, 11–25.

    Article  CAS  PubMed  Google Scholar 

  • Zald, D. H., & Depue, R. A. (2001). Serotonergic functioning correlates with positive and negative affect in psychiatrically healthy males. Personality and Individual Differences, 30, 71–86.

    Article  Google Scholar 

  • Zapolski, T. C. B., Cyders, M. A., & Smith, G. T. (2009). Positive urgency predicts illegal drug use and risky sexual behavior. Psychology of Addictive Behaviors, 23, 348–354.

    Article  PubMed  PubMed Central  Google Scholar 

  • Zastrow, A., Kaiser, S., Stippich, C., Walther, S., Herzog, W., Tchanturia, K., …, Friederich, H. (2009). Neural correlates of impaired cognitive-behavioral flexibility in anorexia nervosa. The American Journal of Psychiatry, 166, 608–616.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carolyn M. Pearson .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Pearson, C.M., Guller, L., Smith, G.T. (2014). Dimensions of Personality and Neuropsychological Function in Eating Disorders, Substance Use Disorders, and Addictions. In: Brewerton, T., Baker Dennis, A. (eds) Eating Disorders, Addictions and Substance Use Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45378-6_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-45378-6_6

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-45377-9

  • Online ISBN: 978-3-642-45378-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics