REITHERA

Congratulations to Sabin Vaccine Institute on the launch of the Phase 2 clinical trial of their Sudan ebolavirus disease vaccine candidate! The Phase 2 trial for a Marburg vaccine is already underway. Sabin plans to hold similar-stage trials for the two vaccines in the U.S. next year. ReiThera is proud to serve as the manufacturing partner for the ChAd3-SUDV and ChAd3-MARV vaccines utilized in these trials. Read the full release: https://lnkd.in/eshgg28N   #gmp #biotech #biotechnology #genetherapy #cellandgenetherapy #advancedtherapies

🧬 Navigating the Complexities of Lentiviral Vector Production 🧩 Lentiviral vectors are one of the foundational technologies of CGT. However, the path to their effective production faces challenges. Adriano Leuzzi highlights the key hurdles: 🔍 Challenges: Scalability and Productivity: Ensuring the right cell line, media, and transfection reagents deliver plasmids efficiently. Environmental Sensitivity: Lentiviral vectors are highly sensitive to temperature, pH changes, and shear forces, complicating the production process. Process Yield and Quality: Meeting regulatory requirements for safety, purity, and efficacy while optimizing yield. Which emerging bioprocessing technologies can offer solutions to these challenges? 💡 Innovative Solutions: High-Titer Suspension Cells: Transitioning to these cells can simplify scale-up in bioreactors and enhance downstream purification. Single-Use Bioreactors and Modular Platforms: These ensure easier scale-up and successful tech-transfer, maximizing overall platform success. Advanced Process Control Software: Introducing dedicated software can mitigate fluctuations in productivity and improve critical quality attributes. Artificial Intelligence: Leveraging AI and machine learning can streamline vector production, enhancing efficiency and focusing on patient outcomes. Discover how these advancements can optimize lentiviral vector production and drive forward the future of gene therapy. 👉 Full article: https://lnkd.in/dx7fD2BH #gmp #biotech #biotechnology #genetherapy #cellandgenetherapy #advancedtherapies

This year has been very busy with international congresses. Drug Discovery World has covered the main events so far. Read our account of the ASGCT meeting by Angelo Raggioli, PhD, where he discusses efforts to enhance scalability, vector purification, and the elimination of residual products👇 https://lnkd.in/eSbjeHcy #gmp #biotech #biotechnology #genetherapy #cellandgenetherapy #advancedtherapies

We've concluded our first ReiThera padel competition. After countless games, we finally celebrate the tournament winners: Federico Napolitano and Sara Bassani! 🎉🏆 Well done to their worthy opponents: Adriano Leuzzi and Stefania Cecere and to the final pair on the podium: Roberto Pani and Martina D’amico 👏 Huge congratulations to our winners, and the rest of us can keep practicing for next year. 🎾

We are hiring! Read the job application to see if you have the relevant technical skills and experience to begin your journey with us! Send your application to application@reithera.com.

Investing in our future: Gene therapy is set to revolutionize healthcare, pushing the market towards $44.7B by 2032. Explore how the sector is advancing genetic disease treatments! 🔬 Read our roundtable contribution: https://lnkd.in/g3C3Dj7B #gmp #biotech #biotechnology #genetherapy #cellandgenetherapy #advancedtherapies

Dive into our latest bioprocessing article to explore the challenges in scalability and purification, along with insights into cell line advancements, manufacturing hurdles, and the role of single-use technologies for process optimization 👇 Article: https://lnkd.in/devTHr4y #gmp #biotech #biotechnology #genetherapy #cellandgenetherapy #advancedtherapies

🌈 Diverse and inclusive representation matters. Celebrating Pride Month is more than a moment— ReiThera is committed to fostering respect, belonging, and championing the unique identities within our communities and workplaces. Together, we can make every month a Pride month. #reitherian

Adriano Leuzzi has been invited to speak at The Future of Bio/Pharmaceutical Analysis Online Summit 2024 event taking place on 20 June 2024. Topic: CMC considerations for cell and gene therapies 🧬 What can the audience expect to learn more about? •  CMC aspects related to gene therapy medical products •  Main challenges and potential solutions •  Viral vector technologies   Thanks to the organizers, European Pharmaceutical Review, for the invitation. #gmp #biotech #biotechnology #genetherapy #cellandgenetherapy #advancedtherapies

🚀 Announcement: Many of our staff are now members of the newly created Italian society for cell and gene therapy, SITGEC. Why has it been created? • 🌟 Groundbreaking Growth: To foster innovation in gene and cell therapy, a rapidly advancing field. • 🇮🇹 Italian Excellence: Italian scientists are internationally acclaimed for pioneering contributions since the '90s. • 🧬 Life-Changing Impact: Thousands, including many in Italy, benefit from advanced therapies for cancer, rare diseases, and more. • 🏥 Clinical Leadership: Italy has developed and trialed several ATMP drugs, with five already marketed in Europe/US! • 🤝 Collaboration & Growth: SITGEC is designed to support and expand these cutting-edge treatments. The creation of the Society is particularly timely, given that the upcoming ESGCT Congress will be held in Rome in October, where ReiThera will be participating as Platinum sponsors. #gmp #biotech #biotechnology #genetherapy #cellandgenetherapy