👐 The Human Technopole's National Facilities are now open to the national scientific community! External users affiliated with universities, IRCCS, and public research entities can access our state-of-the-art technological hubs for free through open calls 👉 https://lnkd.in/d49j-WUX 🔬 HT National Facilities offer open access to cutting-edge technologies in the fields of genomics, genome engineering and disease modelling, imaging, structural biology, and data handling and analysis. 👩🔬 👨🔬 Our mission is to support the scientific community by providing access to advanced technologies and expertise, training programmes, and technology/method development projects, with the ultimate goal of increasing the impact of Italian research on an international level. 🔎 Access is granted based on the principles of scientific excellence, with the aim of supporting high-quality research. Watch the video to discover the access modalities and timelines.
Human Technopole
Servizi di ricerca
Milan, Lombardy 33.972 follower
Il nuovo istituto italiano di ricerca per le Scienze della Vita, situato nel cuore di MIND.
Chi siamo
Human Technopole svilupperà approcci personalizzati a medicina e nutrizione, per contrastare il cancro e le malattie neuro-degenerative integrando la genomica su larga scala con l'analisi di complessi sistemi di dati e lo sviluppo di nuove tecniche diagnostiche. La Fondazione avrà un approccio interdisciplinare basato sulla creazione e condivisione delle conoscenze per promuovere l'innovazione nel settore sanitario. Un approccio che combinerà diverse aree: dalla genomica alla ricerca traslazionale e di base, dall'analisi, all'introduzione di tecnologie sostenibili, dai dispositivi medici all'elaborazione di dati socio-economici per fornire nuove soluzioni analitiche per i responsabili delle decisioni di politiche pubbliche. A regime, Human Technopole sarà un'infrastruttura di ricerca nazionale su larga scala con oltre 30.000 m2 di laboratori interdisciplinari: scienze dei dati, genomica, neuroscienze, agro-alimentare, biologia computazionale e strutturale. Impiegherà oltre 1000 scienziati in diversi campi tra cui biologi, bio-informatici, clinici, chimici, ingegneri, matematici e informatici che lavoreranno insieme su ricerca di rilevanza bio-medica. Human Technopole sarà attivamente impegnata nella divulgazione delle ricerche scientifiche svolte e delle conquiste in tema di salute, diffondendo nei cittadini la consapevolezza che il progresso scientifico è un bene comune.
- Sito Web
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https://humantechnopole.it/en/
Link esterno per Human Technopole
- Settore
- Servizi di ricerca
- Dimensioni dell’azienda
- 201-500 dipendenti
- Sede principale
- Milan, Lombardy
- Tipo
- Non profit
- Data di fondazione
- 2018
- Settori di competenza
- Genomics, Proteomics, Metabolomics, Metagenomics, Imaging, DataScience, Bioinformatics, Immunology, Cancer, Neurobiology, Neurodegeneration, Nutrition, Agriculture, Food, Nanomaterials, Nanotechnology, Network Pharmacology, High Performance Computing, Economics, Society, Health e Life Sciences
Località
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Principale
Viale Rita Levi-Montalcini, 1
Milan, Lombardy 20157, IT
Dipendenti presso Human Technopole
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Piero Carninci
Head of Genomics Research Center, Functional Genomics Programme at Human Technopole
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Gianmario Verona
Gianmario Verona è un influencer Professor of Management at Università Bocconi, Chairman at Fondazione Human Technopole
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Carlos Fernández San Millán
Executive, CIO | Head of ICT & Digitisation
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Luisa Zuccolo
Aggiornamenti
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👐 "In the NF, collaboration is not optional: it's part of our DNA" 🧐 Meet Alberto Riva, Head of the National Facility for Data Handling and Analysis. He tells us about how we move from raw data to advances in scientific knowledge, the challenges posed by AI, and the importance of being able to speak different scientific languages. Read the interview 👉 https://lnkd.in/dGfJVaKm
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Utilising data from 2,023 bowel cancers from the 100,000 Genomes Project led by Genomics England and NHS England, an international team of scientists, including our Andrea Sottoriva (Head of Computational Biology), has provided the most comprehensive analysis to date of the genetic makeup of colorectal cancer and its responses to treatment. The pioneering study, published in Nature, was led by the University of Oxford, The Institute of Cancer Research and the The University of Manchester. “Thanks to the power of DNA sequencing of large groups of patients we were able to find previously unknown cancer genetic alterations that could be used as a target for therapy. It was also very important to find peculiar genetic mutations in rare subgroups of cancers, some of which occur at early age, which may be caused by lifestyle.” - Andrea Sottoriva.
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👥 In science history, there are many examples of scientists who made sensational discoveries, yet no one remembers their names. Why? They were probably not good communicators. 📣 We discussed the importance of effective science communication, along with tips and tricks for good dissemination of research, with Ralf Dahm (Director of Scientific Management, Institute of Molecular Biology (IMB), Germany), speaker at the first HT PhD and Postdoc Symposium.
#MeetTheSpeaker - Effective Science Communication with Ralf Dahm
https://www.youtube.com/
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🔬 A new multiscale study by our Giuseppe Testa Group reveals how 7q11.23 CNV affects neuronal differentiation and function in Williams-Beuren and 7q microduplication syndromes. Published in The Journal of Clinical Investigation. 🧐 These findings deepen our understanding of the molecular pathways underlying neurodevelopmental disorders and pave the way for new treatments.
Multiscale investigation of 7q11.23 copy number variation in neurodevelopmental disorders - Human Technopole
https://humantechnopole.it/en/
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🧠🔬 Our Giuseppe Testa Group (Neurogenomics), with international colleagues from Università degli Studi di Milano, has studied a method for engineering the parasite Toxoplasma gondii as a vehicle for transporting therapeutic proteins to the central nervous system, offering a potential solution to the challenges of treating neurological diseases. 📰 The publication is published in Nature Microbiology. “The next steps can now begin to further optimize the system's efficiency and address potential safety issues associated with using a parasite as a vector. We are very pleased that such a fruitful international collaboration provides a promising new approach for protein delivery to the central nervous system via Toxoplasma gondii, offering a potential solution to the challenges posed by treating neuropsychiatric diseases, especially those of developmental age,” - Giuseppe Testa.
Engineered Parasite Delivers Therapeutic Proteins to Central Nervous System - Human Technopole
https://humantechnopole.it/en/
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🔬 Utilizing cryo-electron tomography, mass spectrometry, and AlphaFold, our Gaia Pigino Group modeled retrograde IFT trains in Chlamydomonas reinhardtii cilia. The study, published in Cell, unveils how anterograde IFT trains switch to retrograde at the ciliary tip, offering insights into direction-specific cargo binding and transport. 🧐 Their findings show that retrograde trains are highly flexible and differ significantly from anterograde trains, with complete disassembly and reassembly at the ciliary tip. The research advances our understanding of ciliary function and could lead to new treatments for ciliopathies.
Mechanism of ciliary train switch and cargo recognition - Human Technopole
https://humantechnopole.it/en/
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👀 "First thing first: Γνῶθι σαυτόν (know thyself)" 🧐 Meet Paolo Swuec, Head of the National Facility for Structural Biology of Human Technopole, who tells us how his passion for unraveling mysteries that impact human health led him to head the first Italian Cryo-EM Facility. Read the interview 👉 https://lnkd.in/dDiUvwXS
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🎉 Congratulations to the Craig Glastonbury Group and Nicole Soranzo, awarded by the Chan Zuckerberg Initiative to develop a machine learning model that enables broad disease, trait and biomarker prediction from single-cell data while simultaneously identifying relevant implicated cell types.
Chan Zuckerberg Initiative grant to the Glastonbury Group - Human Technopole
https://humantechnopole.it/en/
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L'Italia vanta una tradizione accademica di eccellenza, ma per trattenere i nostri “cervelli” e renderli competitivi a livello globale, è essenziale investire in ricerca, offrire condizioni migliori ai ricercatori e impegnarsi nella creazione di una cultura della condivisione del dato. Con l'avvio delle nuove aree di ricerca e l'apertura delle Piattaforme Nazionali, Human Technopole è al centro di una trasformazione che mira a valorizzare i talenti e rendere il nostro Paese piú innovativo e competitivo. Per Panorama della Sanità, il nostro direttore Marino Zerial esplora le sfide della ricerca italiana e i risultati raggiunti da HT.
Ricerca, “È necessario creare una cultura della condivisione del dato” | Panorama della Sanità
https://panoramadellasanita.it/site