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Comprehensive mapping and modelling of the rice regulome landscape unveils the regulatory architecture underlying complex traits
Unraveling the regulatory mechanisms that govern complex traits is pivotal for advancing crop improvement. Here we present a comprehensive regulome...
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Stability of ecologically scaffolded traits during evolutionary transitions in individuality
Evolutionary transitions in individuality are events in the history of life leading to the emergence of new levels of individuality. Recent studies...
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Hijacking of N-fixing legume albumin-1 genes enables the cyclization and stabilization of defense peptides
The legume albumin-1 gene family, arising after nodulation, encodes linear a- and b-chain peptides for nutrient storage and defense. Intriguingly, in...
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Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2
ASCT2 is an obligate exchanger of neutral amino acids, contributing to cellular amino acid homeostasis. ASCT2 belongs to the same family (SLC1) as...
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The superiority of innovative spiral-interdigital microelectrode pattern in increasing the sensitivity of tracing synchronization via serum starvation in cellular metabolism
In order to investigate the changes in the properties of the cell culture solution in the effect of cell synchronization via cell starvation (for 12,...
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Thermal management towards ultra-bright and stable perovskite nanocrystal-based pure red light-emitting diodes
Despite the promising candidacy of perovskite nanocrystals for light-emitting diodes, their pure red electroluminescence is hindered by low saturated...
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Shearo-caloric effect enhances elastocaloric responses in polymer composites for solid-state cooling
Room-temperature elastocaloric cooling is considered as a zero-global-warming-potential alternative to conventional vapor-compression refrigeration...
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A whole-cell platform for discovering synthetic cell adhesion molecules in bacteria
Developing programmable bacterial cell-cell adhesion is of significant interest due to its versatile applications. Current methods that rely on...
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Prion-like domain mediated phase separation of ARID1A promotes oncogenic potential of Ewing’s sarcoma
Liquid-liquid phase separation (LLPS) facilitates the formation of membraneless organelles within cells, with implications in various biological...
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The role of plume-lithosphere interaction in Hawaii-Emperor chain formation
Paleolatitudes of volcanic rocks reveal that prominent changes in volcanic trend of the Hawaii-Emperor hotspot chain represent meridional migration...
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Passively sensing smartphone use in teens with rates of use by sex and across operating systems
Youth screen media activity is a growing concern, though few studies include objective usage data. Through the longitudinal, U.S.-based Adolescent...
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Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: evidence from the PoCOsteo study
Cardiometabolic risk factors increase the chance of developing cardiovascular disease (CVD) and type 2 diabetes. Most CVD risk factors are influenced...
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A frugal CRISPR kit for equitable and accessible education in gene editing and synthetic biology
Equitable and accessible education in life sciences, bioengineering, and synthetic biology is crucial for training the next generation of scientists,...
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Kinesin-14 HSET and KlpA are non-processive microtubule motors with load-dependent power strokes
Accurate chromosome segregation during cell division relies on coordinated actions of microtubule (MT)-based motor proteins in the mitotic spindle....
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Fractal evolution characteristics of fracture meso-damage in uniaxial compression rock masses using bonded block model
With regard to deep mining in metal mines, an investigation into the failure mode of deep fractured rock masses and their corresponding acoustic...
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Proteomics and machine learning in the prediction and explanation of low pectoralis muscle area
Low muscle mass is associated with numerous adverse outcomes independent of other associated comorbid diseases. We aimed to predict and understand an...
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Impact of Bi2O3 on prepared nano (SiO2-Na2O-CaO-B2O3) glass as radiation shielding material
Melt quenching technique was used to create Bismuth Boro-Silicate nano glasses with compositions of 45SiO 2 -10CaO- 25Na 2 O- xBi 2 O 3 - (20-x) B 2 O 3 (where...
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Spatiotemporal evolution of carbon budget and carbon compensation zoning of urban agglomerations in the Yellow River Basin
As a crucial industrial, agricultural, and energy base in China, the urban agglomerations in the Yellow River Basin (YRB) have faced increasingly...
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Machine learning-based biomarker screening for acute myeloid leukemia prognosis and therapy from diverse cell-death patterns
Acute myeloid leukemia (AML) exhibits pronounced heterogeneity and chemotherapy resistance. Aberrant programmed cell death (PCD) implicated in AML...
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Olfactory sampling volume for pheromone capture by wing fanning of silkworm moth: a simulation-based study
Odours used by insects for foraging and mating are carried by the air. Insects induce airflows around them by flapping their wings, and the...
