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Hydrogels for Musculoskeletal Tissue Engineering
The advancements in scaffold-supported cell therapy for musculoskeletal tissue engineering have been truly dramatic in the last couple of decades....
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Regeneration of Articular Cartilage
Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead...
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Tissue Engineering Strategies for Bone Regeneration
Bone loss due to trauma or disease is an increasingly serious health problem. Current clinical treatments for critical-sized defects are problematic...
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Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules
Growth factors are increasingly utilized to promote regeneration of lost or compromised tissues and organs. However, current strategies applying...
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Biopolyesters in Tissue Engineering Applications
Tissue engineering is a rapidly growing interdisciplinary field of research focused on the development of vital autologous tissue through the use...
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Interfaces to Control Cell-Biomaterial Adhesive Interactions
Cell adhesion to adsorbed proteins and adhesive sequences engineered on surfaces is crucial to cellular and host responses to implanted devices,...
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Simultaneous In Vivo Regeneration of Neodermis, Epidermis, and Basement Membrane
Full-thickness skin loss does not undergo complete spontaneous regeneration in mammals. To restore the normal function of skin, dermal and epidermal...
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Heart Valve Regeneration
The valves of the heart cannot regenerate spontaneously. Therefore, heart valve disease generally necessitates surgical repair or replacement of the...
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Regeneration of Urologic Tissues and Organs
Patients suffering from a variety of urologic diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor...
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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Self-Assembling Nanopeptides Become a New Type of Biomaterial
Combining physics, engineering, chemistry and biology, we can now design, synthesize and fabricate biological nano-materials at the molecular...
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Modulating Extracellular Matrix at Interfaces of Polymeric Materials
As extracellular matrices (ECM) closely interact with cells in living tissues and, through this, influence essentially any aspect of life...
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Spinal Cord Regeneration
Repairing the damaged spinal cord has for a long time eluded neuroscientists. Few other achievements in neuroscience would have such a tremendous...
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Peripheral Nerve Regeneration
The nerve chamber model has dominated the experimental study of peripheral nerve (PN) regeneration with animal models as well as in several clinical...
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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
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Adult-onset deletion of ATP13A2 in mice induces progressive nigrostriatal pathway dopaminergic degeneration and lysosomal abnormalities
Although most cases of Parkinson’s disease (PD) are sporadic, mutations in over 20 genes are known to cause heritable forms of the disease. Recessive...
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Comparative speed of kill provided by lotilaner (Credelio™), sarolaner (Simparica Trio™), and afoxolaner (NexGard™) to control Amblyomma americanum infestations on dogs
BackgroundCanine acaricides with rapid onset and sustained activity can reduce pathogen transmission risk and enhance pet owner experience. This...
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Detection of neoplastic-immune hybrid cells with metastatic properties in uveal melanoma
BackgroundUveal melanoma is the most common non-cutaneous melanoma and is an intraocular malignancy affecting nearly 7,000 individuals per year...
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Down-regulation of NF-κB signalling by methanolic extract of Viola odorata (L.) attenuated in vivo inflammatory and angiogenic responses
Intractable inflammation plays a key role in the progression of autoimmune diseases such as rheumatoid arthritis. Oedema and angiogenesis are the...
