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  1. Hydrogels for Musculoskeletal Tissue Engineering

    The advancements in scaffold-supported cell therapy for musculoskeletal tissue engineering have been truly dramatic in the last couple of decades....
    Shyni Varghese, Jennifer H. Elisseeff in Polymers for Regenerative Medicine
    Chapter
  2. Regeneration of Articular Cartilage

    Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead...
    B. Kinner, R. M. Capito, M. Spector in Regenerative Medicine II
    Chapter
  3. Tissue Engineering Strategies for Bone Regeneration

    Bone loss due to trauma or disease is an increasingly serious health problem. Current clinical treatments for critical-sized defects are problematic...
    Amit S. Mistry, Antonios G. Mikos in Regenerative Medicine II
    Chapter
  4. Polymeric Systems for Bioinspired Delivery of Angiogenic Molecules

    Growth factors are increasingly utilized to promote regeneration of lost or compromised tissues and organs. However, current strategies applying...
    Claudia Fischbach, David J. Mooney in Polymers for Regenerative Medicine
    Chapter
  5. Biopolyesters in Tissue Engineering Applications

    Tissue engineering is a rapidly growing interdisciplinary field of research focused on the development of vital autologous tissue through the use...
    Chapter
  6. Interfaces to Control Cell-Biomaterial Adhesive Interactions

    Cell adhesion to adsorbed proteins and adhesive sequences engineered on surfaces is crucial to cellular and host responses to implanted devices,...
    Andrés J. García in Polymers for Regenerative Medicine
    Chapter
  7. Simultaneous In Vivo Regeneration of Neodermis, Epidermis, and Basement Membrane

    Full-thickness skin loss does not undergo complete spontaneous regeneration in mammals. To restore the normal function of skin, dermal and epidermal...
    Charles E. Butler, Dennis P. Orgill in Regenerative Medicine II
    Chapter
  8. Heart Valve Regeneration

    The valves of the heart cannot regenerate spontaneously. Therefore, heart valve disease generally necessitates surgical repair or replacement of the...
    Elena Rabkin-Aikawa, John E. Mayer Jr., Frederick J. Schoen in Regenerative Medicine II
    Chapter
  9. Regeneration of Urologic Tissues and Organs

    Patients suffering from a variety of urologic diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor...
    Anthony Atala in Regenerative Medicine II
    Chapter
  10. Conjunctival Regeneration

    Mark P. Hatton, Peter A. D. Rubin in Regenerative Medicine II
    Chapter
  11. Current Topics Regarding the Function of the Medial Temporal Lobe Memory System

    The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
    Chapter
  12. Self-Assembling Nanopeptides Become a New Type of Biomaterial

    Combining physics, engineering, chemistry and biology, we can now design, synthesize and fabricate biological nano-materials at the molecular...
    Xiaojun Zhao, Shuguang Zhang in Polymers for Regenerative Medicine
    Chapter
  13. Modulating Extracellular Matrix at Interfaces of Polymeric Materials

    As extracellular matrices (ECM) closely interact with cells in living tissues and, through this, influence essentially any aspect of life...
    Carsten Werner, Tilo Pompe, Katrin Salchert in Polymers for Regenerative Medicine
    Chapter
  14. Spinal Cord Regeneration

    Repairing the damaged spinal cord has for a long time eluded neuroscientists. Few other achievements in neuroscience would have such a tremendous...
    Poonam Verma, James Fawcett in Regenerative Medicine II
    Chapter
  15. Peripheral Nerve Regeneration

    The nerve chamber model has dominated the experimental study of peripheral nerve (PN) regeneration with animal models as well as in several clinical...
    Mei Zhang, Ioannis V. Yannas in Regenerative Medicine II
    Chapter
  16. Effects of Sex Steroids on Innate and Adaptive Immunity

    Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive...
    S. Ansar Ahmed, Ebru Karpuzoglu, Deena Khan in Sex Hormones and Immunity to Infection
    Chapter
  17. A Randomised Controlled Trial of SFX-01 After Subarachnoid Haemorrhage — The SAS Study

    SFX-01 is a novel drug for clinical delivery of sulforaphane (SFN). SFN is a potent nuclear factor erythroid 2-related factor 2 activator that...

    Ardalan Zolnourian, Patrick Garland, ... Diederik Bulters in Translational Stroke Research
    Article Open access 19 July 2024
  18. INTS11-related neurodevelopmental disorder: a case report and literature review

    Background

    INTS11 is a critical catalytic component of the Integrator complex that regulates RNA polymerase II termination and modulates gene...

    Lihua Jiang, Yilong Wang, ... Zhefeng Yuan in Journal of Human Genetics
    Article 19 July 2024
  19. Rumen and hindgut microbiome regulate average daily gain of preweaning Holstein heifer calves in different ways

    Background

    The average daily gain (ADG) of preweaning calves significantly influences their adult productivity and reproductive performance....

    Sheng-yang Xu, Xiao-ran Feng, ... Yan Tu in Microbiome
    Article Open access 19 July 2024
  20. Salvage radiotherapy for locally recurrent cervical and endometrial carcinoma: clinical outcomes and toxicities

    Background

    The management of locally recurrent gynecological carcinoma remains a challenge due to the limited availability of data. This study aims to...

    Hui Cong, Xiaojing Yang, ... Jie Fu in BMC Cancer
    Article Open access 19 July 2024
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