Cellular organelles form an interconnected and dynamic network that orchestrates cellular functions. Using a multispectral imaging and computational analysis approach (‘OrgaPlexing’), a study now identifies multi-organelle units as crucial regulators of metabolic reprogramming in primary macrophages upon inflammatory stimuli.
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Pilic, J., Kleele, T. An organelle tango controls lipid metabolism. Nat Cell Biol (2024). https://doi.org/10.1038/s41556-024-01441-8
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DOI: https://doi.org/10.1038/s41556-024-01441-8