HKCeND - Hong Kong Center for Neurodegenerative Diseases (香港神經退行性疾病中心)

We were honored to participate in the prestigious Reception for I&T Awards 2024, organized by the Innovation and Technology Commission at the Central Government Office on 15 Jul 2024. More than 300 representatives from the local innovation and technology (I&T) sector, including scientists from our two research projects, were commended for their remarkable achievements in international competitions and exhibitions over the past year. We were pleased to showcase one of our award-winning inventions, "sST2 as a novel therapeutic target for Alzheimer's disease". The Chief Executive, Mr. John Lee, led a VIP tour of our showcase and lauded the significance of our work. At HKCeND, we are dedicated to propelling our cutting-edge research and translating our scientific breakthroughs into tangible solutions that contribute to developing Hong Kong into an international I&T center. #HKCeND #HKUST #GenevaInventions #Innovation #Technology #ResearchExcellence

We are delighted to share that our team has been honored with 3 awards at the International Exhibition of Inventions Geneva 2024. One of our award-winning inventions is an innovative strategy targeting soluble ST2 (sST2), a blood protein, for the development of Alzheimer's disease therapeutics. This invention garnered the Prize of the Chinese Delegation for Invention and Innovation, as well as the Gold Medal with Congratulations of the Jury. Moreover, we are proud to have been awarded a Gold Medal for our novel "one-for-many" genome editing approach, designed to treat familial Alzheimer's disease. We are deeply grateful for the global recognition of our scientific breakthroughs and remain dedicated to translating our innovations into practical solutions that benefit society. #HKCeND #HKUST #GenevaInventions #Innovation #ResearchandDevelopment #KnowledgeTransfer

🎥 Prof. Nancy IP and Prof. John HARDY share the current and future landscape of Alzheimer's disease (AD) management in this 2-min video. Their insights highlight the crucial importance of developing a simple and accurate blood test for the early detection of AD and mild cognitive impairment (MCI), as well as the significance of international collaboration in addressing this global health challenge. The highly accurate diagnostic blood test developed by the scientists at #HKUST and #HKCeND is a groundbreaking innovation, paving the way for early diagnosis and personalized treatment of AD on a global scale. Watch the video now. #AlzheimersDisease #MildCognitiveImpairment #EarlyDiagnosis #BloodTest #Innovation #InternationalCollaboration 葉玉如教授和John HARDY教授在這段2分鐘的影片中分享了阿爾茲海默症疾病管理的現狀與未來前景。他們的見解強調了開發簡單且精準的血液測試對於早期診斷阿爾茲海默症和輕度認知障礙至關重要���以及強調了國際合作在應對這一全球健康挑戰方面的重要性。 由香港科技大學和香港神經退行性疾病中心的科學家開發的血液檢測是一項突破性的創新科技，為全球阿爾茲海默症的早期診斷和個人化治療開闢了新道路。 立即觀看影片！

The #HKUST and #HKCeND scientists have developed a revolutionary blood test that can accurately identify Alzheimer's disease (AD) and its early stage, known as mild cognitive impairment (MCI). This blood test is a game-changer for AD diagnosis, providing a global solution that can benefit diverse ethnic populations. ✅ High accuracy: achieve a remarkable accuracy rate of over 96% for AD and 87% for MCI ✅ Brain damage detection: indicate the development of brain damage (i.e. Aβ pathology) ✅ Diverse populations: applicable across different ethnic populations, including Chinese and European ✅ Comprehensive analysis: simultaneously measure the levels of 21 proteins in multiple crucial biological pathways, achieving multi-dimensional analysis of an individual's AD status. At HKCeND, we are dedicated to translating our research discoveries into innovative solutions that shape a healthier future. This blood test is a significant step towards early AD diagnosis and personalized treatment strategies. Discover more: https://lnkd.in/gHy2b92u #AlzheimersDisease #MildCognitiveImpairment #EarlyDiagnosis #BloodTest #ResearchBreakthrough #Innovation 香港科技大學和香港神經退行性疾病中心的科學家開發了一種突破性的血液測試，可準確識別阿爾茲海默症及其早期階段，即輕度認知障礙。 這項血液測試將革新阿爾茲海默症的診斷，為疾病的早期檢測提供一個切實的解決方案，造福不同人群。 ✅ 高準確率：檢測阿爾茲海默症的準確率超過96%，檢測輕度認知障礙的準確率超過87% ��� 腦損傷檢測：這個測試可揭示Aβ蛋白沉積導致腦損傷的程度 ✅ 適用於不同人群，包括中國和歐洲人群 ✅ 全面的病情分析：透過同時測量21種參與不同關鍵生理過程的血液蛋白濃度，實現多維度、更全面的病情評估 我們中心致力於將科研成果轉化為創新解決方案，讓人們活得更健康。這項血液檢測在推動阿爾茲海默症的早期診斷和個人化治療方面邁出了重要的一步。 了解更多：https://lnkd.in/gVgwrQQA

May the Year of the Dragon bring you and your loved ones an abundance of good health and great fortune. Embodying strength, luck, and vitality, let us harness the dragon's energy and wisdom to transform brilliant ideas into impactful innovations that shape a brighter future for all! #HKCeNDgreetings #CNY2024 #YearOfTheDragon #Innovation #Healthcare

香港神經退行性疾病中心助理主任張曉東教授日前接受《大公報》的專訪，分享了他在抗衰老領域的科研工作，當中談及其研究團隊在成體幹細胞衰老方面的科研成果。 張教授分享了其研究團隊最近有關CPEB4蛋白的重大科研進展。相關研究成果揭示了CPEB4蛋白在肌肉幹細胞中維持線粒體功能和防止細胞衰老的重要作用，為逆轉衰老的研發提供了新方向。目前，團隊正深入探究將CPEB4作為藥物靶點，致力於開發提高線粒體功能和能量產出的藥物。同時，團隊正在開發新的藥物篩選平台，以研發針對肺纖維化、肌肉減少症等與老化相關疾病的藥物，旨在改善長者的健康，應對全球人口老齡化問題。 瀏覽相關媒體報導： 印刷版本：https://lnkd.in/grZc8kFH 網上版本：https://lnkd.in/gE4hXpQx Our Assistant Center Director, Prof. Tom Cheung, was recently featured in an interview article by Ta Kung Pao, where he shared his research journey in the field of anti-aging. In the interview, Prof. Cheung discussed the significant progress made by his research team in the study of adult stem cell aging. One of the scientific breakthroughs was the discovery of the CPEB4 protein and its crucial role in maintaining mitochondrial functions and preventing cellular senescence. This groundbreaking finding offers promising insights into the reversal of the aging process. The team is currently investigating the potential of CPEB4 as a therapeutic target, to develop drugs for boosting mitochondrial function and energy production. The team is also developing a novel drug screening platform to address age-related diseases such as pulmonary fibrosis and sarcopenia, aiming to improve the health and well-being of the elderly and tackle the challenges posed by the aging population. Read more: Print version (in Chinese): https://lnkd.in/grZc8kFH Online version (in Chinese): https://lnkd.in/gE4hXpQx #HKCeND #HKUST #AgingPopulation #HealthyAging #CPEB4

🔬 Unlock the secrets of stem cell aging and rejuvenation! Join us for a captivating lecture by renowned neurologist, Prof. Thomas Rando. This event, co-organized by the HKUST Jockey Club Institute for Advanced Study and HKCeND, is open to the public. Don't miss the opportunity to discover the mechanisms behind stem cell aging and explore fascinating ways to reverse the clock on stem cell function! 📅 Date: 4 Jan 2024 ⏰ Time: 3:00 - 4:30pm 📍 Venue: Kaisa Group Lecture Theater (IAS LT), Lo Ka Chung Building, Lee Shau Kee Campus, HKUST Learn more about the lecture: https://lnkd.in/gJ7E5F4m #HKCeND #HKUST #StemCellAging #StemCellResearch #Rejuvenation

Christmas is just around the corner! 🎄✨ What could be more joyful than coming together as a team and celebrating this magical season with our loved ones? We had a wonderful time during our team building event on 15 Dec 2023, filled with happiness, laughter, and blessings. We are grateful for the dedication and hard work that each member of our team has put in throughout the year. The party was a blast, with exciting lucky draws and delicious refreshments. As the year comes to a close, HKCeND team would like to extend our warmest wishes to all of you for a happy holiday season! Let's regroup and embark on another year of game-changing innovations ahead! 🚀✨ #HKCeNDgreetings #MerryChristmas #Christmas2023

We are delighted to participate in the InnoHK Summit 2023 at Hong Kong Science Park today. Our Center Director, Prof. Nancy Ip, took the stage to share our groundbreaking R&D breakthroughs in developing diagnostic test and therapeutic strategies for Alzheimer's disease. With a relentless drive for innovation, we are dedicated to bringing impactful healthcare solutions that benefit society. At our booth, our researchers engaged in vibrant sharing, exchanging insights and showcasing our R&D achievements to visitors from the industry and academia. As one of the centers under the InnoHK initiative, we remain committed to fostering global research collaboration, propelling scientific and technological advancements, and translating our R&D outcomes into tangible solutions. #HKCeND #InnoHKSummit2023 #HealthcareInnovation #ResearchandDevelopment #ResearchBreakthroughs

Yesterday, we were delighted to share our latest R&D projects and breakthroughs with a distinguished Shaw Laureate in Life Science and Medicine, along with approximately 20 young scientists. Our researchers took the lead, guiding the guests through a lab tour. They showcased our state-of-the-art research facilities, giving a glimpse into the cutting-edge work happening at HKCeND. It was a great opportunity to exchange knowledge, foster connection, and inspire each other towards greater scientific achievements. #HKCeND #HongKongLaureateForum #innovation #scienceandtechnology #researchanddevelopment