Kite, T. A. et al. (2024) Complex percutaneous coronary intervention in patients unable to undergo coronary artery bypass grafting during the COVID-19 pandemic: insights from the UK-ReVasc Registry. Journal of Invasive Cardiology, (doi: 10.25270/jic/24.00030) (PMID:38471155) (Early Online Publication)
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Abstract
Cardiac surgery for coronary artery disease was dramatically reduced during the first wave of the COVID-19 pandemic. Many patients with disease ordinarily treated with coronary artery bypass grafting (CABG) instead underwent percutaneous coronary intervention (PCI). We sought to describe 12-month outcomes following PCI in patients who would typically have undergone CABG. Between March 1 and July 31, 2020, patients who received revascularization with PCI when CABG would have been the primary choice of revascularization were enrolled in the prospective, multicenter UK-ReVasc Registry. We evaluated the following major adverse cardiovascular events at 12 months: all-cause mortality, myocardial infarction, repeat revascularization, stroke, major bleeding, and stent thrombosis. A total of 215 patients were enrolled across 45 PCI centers in the United Kingdom. Twelve-month follow up data were obtained for 97% of the cases. There were 9 deaths (4.3%), 5 myocardial infarctions (2.4%), 12 repeat revascularizations (5.7%), 1 stroke (0.5%), 3 major bleeds (1.4%), and no cases of stent thrombosis. No difference in the primary endpoint was observed between patients who received complete vs incomplete revascularization (residual SYNTAX score £ 8 vs > 8) (P = .22). In patients with patterns of coronary disease in whom CABG would have been the primary therapeutic choice outside of the pandemic, PCI was associated with acceptable outcomes at 12 months of follow-up. Contemporary randomized trials that compare PCI to CABG in such patient cohorts may be warranted.
Item Type: | Articles |
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Additional Information: | Funding: This study received in-kind data management support from the Robertson Center for Biostatistics at The University of Glasgow. |
Keywords: | complex PCI, coronary artery bypass grafting, COVID-19, percutaneous coronary intervention, multivessel disease, revascularization. |
Status: | Early Online Publication |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Berry, Professor Colin and Shaukat, Dr Aadil |
Authors: | Kite, T. A., Chase, A., Owens, C. G., Shaukat, A., Mozid, A. M., O'Kane, P., Routledge, H., Perera, D., Jain, A. K., Palmer, N., Hoole, S. P., Egred, M., Sinha, M. K., Cahill, T. J., Anantharam, B., Byrne, J., Morris, P. D., Kean, S., Sabra, A., Aetesam-Ur-Rahman, M., Mailey, J., Demir, O., Mouyis, K., Abdalwahab, A., Terentes-Printzios, D., Kanyal, R., Curzen, N., Berry, C., Gershlick, A. H., Ladwiniec, A., and on behalf of the UK-ReVasc Registry Investigators, |
College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
Journal Name: | Journal of Invasive Cardiology |
Publisher: | HMP Global Learning Network |
ISSN: | 1557-2501 |
ISSN (Online): | 1557-2501 |
Published Online: | 06 March 2024 |
Copyright Holders: | Copyright © 2024 HMP Global |
First Published: | First published in Journal of Invasive Cardiology 2024 |
Publisher Policy: | Reproduced with the permission of the publisher |
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