Not a DOI

The resolution service at https://doi.org resolves DOIs. You have attempted to resolve highwire/filestream/42184/field_highwire_adjunct_files/0/jitc-2022-004780supp001_data_supplement.pdf, which is not a DOI.

highwire/filestream/42184/field_highwire_adjunct_files/0/jitc-2022-004780supp001_data_supplement.pdf may be a Handle (DOIs are a special sort of Handle). If highwire/filestream/42184/field_highwire_adjunct_files/0/jitc-2022-004780supp001_data_supplement.pdf is a valid Handle you should be able to resolve it at https://hdl.handle.net.