Skip to main content

Advertisement

Log in

Mindfulness-based Group Therapy for Women with Provoked Vestibulodynia

  • ORIGINAL PAPER
  • Published:
Mindfulness Aims and scope Submit manuscript

Abstract

Provoked vestibulodynia (PVD) is the most common cause of painful intercourse in women of reproductive age and research supports psychological approaches in the management of chronic pain. We developed a four-session group treatment for women with PVD that relied mostly on mindfulness meditation skills along with education and some discussion of cognitive theory. A total of 85 women were assigned either to immediate treatment (n = 62; mean age, 39 years) or to a 3-month wait-list condition followed by treatment (n = 23; mean age, 40 years). Questionnaires and a genital pain assessment were administered at pre- and post-treatment, and at 6 months follow-up. Women assigned to the two groups did not significantly differ on any measure at baseline. During the pretreatment wait-list period, there were significant improvements in pain self-efficacy, and non-significant improvements in feelings of helplessness, and sex-related distress. Pain self-efficacy, pain catastrophizing, genital pain induced by a cotton swab exam, pain hypervigilance, and sex-related distress all improved with treatment. There was no change in pain with intercourse. Pretreatment genital pain was the best predictor of post-treatment genital pain. Genital pain at 6-month follow-up was predicted by pretreatment genital pain, change in pain self-efficacy, and number of comorbid chronic pain conditions. Taken together, these findings support the use of a brief mindfulness-based program as a promising treatment for distressing genital pain.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Arck, P. C., Slominski, A., Theoharides, T. C., Peters, E. M. J., & Paus, R. (2006). Neuroimmunology of stress: skin takes center stage. Journal of Investigative Dermatology, 126, 1697–1704.

    Article  PubMed Central  PubMed  Google Scholar 

  • Arnold, L., Bachmann, G. A., Rosen, R., Kelly, S., & Rhoads, G. G. (2006). Vulvodynia: characteristics and associations with comorbidities and quality of life. Obstetrics & Gynecology, 107(3), 617–624.

    Article  Google Scholar 

  • Ayling, K., & Ussher, J. M. (2008). “If sex hurts, am I still a woman?” the subjective experience of vulvodynia in hetero-sexual women. Archives of Sexual Behavior, 37(2), 294–304. doi:10.1007/s10508-007-9204-1.

    Article  PubMed  Google Scholar 

  • Baer, R. A., Smith, G. T., Hopkins, J., Krietemeyer, J., & Toney, L. (2006). Using self-report assessment methods to explore facets of mindfulness. Assessment, 13(1), 27–45.

    Article  PubMed  Google Scholar 

  • Baer, R. A., Smith, G. T., Lykins, E., Button, D., Krietemeyer, J., Sauer, S., et al. (2008). Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment, 15(3), 329–342.

    Article  PubMed  Google Scholar 

  • Basson, R. (2012). The recurrent pain and sexual sequelae of provoked vestibulodynia: a perpetuating cycle. Journal of Sexual Medicine, 9, 2077–2092. doi:10.1111/j.1743-6109.2012.02803.x.

    Article  PubMed  Google Scholar 

  • Beck, A. T., & Beamesderfer, A. (1974). Assessment of depression: the depression inventory. Modern Problems of Pharmacopsychiatry, 7, 151–169.

    Article  PubMed  Google Scholar 

  • Bergeron, S., Binik, Y. M., Khalifé, S., Pagidas, K., Glazer, H. I., Meana, M., et al. (2001). A randomized comparison of group cognitive-behavioral therapy, surface electromyographic biofeedback, and vestibulectomy in the treatment of dyspareunia resulting from vulvar vestibulitis. Pain, 91(3), 297–306.

    Article  PubMed  Google Scholar 

  • Bergeron, S., Khalifé, S., Glazer, H. I., & Binik, Y. M. (2008). Surgical and behavioral treatments for vestibulodynia: two-and-one-half year follow-up and predictors of outcome. Obstetrics & Gynacology, 111(1), 159–166.

    Article  Google Scholar 

  • Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., & Carmody, J. (2004). Mindfulness: a proposed operational definition. Clinical Psychology: Science and Practice, 11(3), 230–241.

    Google Scholar 

  • Black, P. H. (2002). Stress and the inflammatory response: a review of neurogenic inflammation. Brain Behavior, and Immunology, 16, 622–653.

    Article  Google Scholar 

  • Bornstein, J., Tuma, R., Farajun, Y., Azran, A., & Zarfati, D. (2010). Topical nifedipine for the treatment of localized provoked vulvodynia: a placebo-controlled study. The Journal of Pain, 11(12), 1403–1409. doi:10.1016/j.jpain.2010.03.016.

    Article  PubMed  Google Scholar 

  • Bradford, A., & Meston, C. (2007). Correlates of placebo response in the treatment of sexual dysfunction in women: a preliminary report. Journal of Sexual Medicine, 4(5), 1345–1351. doi:10.1111/j.1743-6109.2007.00578.x.

    Article  PubMed Central  PubMed  Google Scholar 

  • Bradford, A., & Meston, C. M. (2009). Placebo response in the treatment of women’s sexual dysfunctions: a review and commentary. Journal of Sex and Marital Therapy, 35(3), 164–181.

    Article  PubMed  Google Scholar 

  • Bradford, A., & Meston, C. M. (2011). Behavior and symptom change among women treated with placebo for sexual dysfunction. Journal of Sexual Medicine, 8(1), 191–201. doi:10.1111/j.1743-6109.2010.02007.x.

    Article  PubMed Central  PubMed  Google Scholar 

  • Brotto, L. A., Basson, R., & Gehring, D. (2003). Psychological profiles among women with vulvar vestibulitis syndrome: a chart review. Journal of Psychosomatic Obstetrics & Gynecology, 24(3), 195–203.

    Article  Google Scholar 

  • Brotto, L. A., Heiman, J. R., Goff, B., Greer, B., Lentz, G. M., Swisher, E., et al. (2008a). A psychoeducational intervention for sexual dysfunction in women with gynecologic cancer. Archives of Sexual Behavior, 37(2), 317–329.

    Article  PubMed  Google Scholar 

  • Brotto, L. A., Basson, R., & Luria, M. (2008b). A mindfulness-based group psychoeducational intervention targeting sexual arousal disorder in women. Journal of Sexual Medicine, 5(7), 1646–1659. doi:10.1111/j.1743-6109.2008.00850.x.

    Article  PubMed  Google Scholar 

  • Brotto, L. A., Erskine, Y., Carey, M., Ehlen, T., Finalyson, S., Heywood, M., et al. (2012). A brief mindfulness-based cognitive behavioral intervention improves sexual functioning versus wait-list control in women treated for gynecologic cancer. Gynecologic Oncology, 125(2), 320–325. doi:10.1016/j.ygyno.2012.01.035.

    Article  PubMed Central  PubMed  Google Scholar 

  • Brotto, L. A., Basson, R., Carlson, M., & Zhu, C. (2013). Impact of an integrated mindfulness and cognitive behavioural treatment for provoked vestibulodynia (IMPROVED): a qualitative study. Sexual and Relationship Therapy, 28(1–2), 3–19. doi:10.1080/14681994.2012.686661.

    Article  Google Scholar 

  • Butler, A. C., Chapman, J. E., Forman, E. M., & Beck, A. T. (2006). The empirical status of cognitive-behavioral therapy: a review of meta-analyses. Clinical Psychology Review, 26(1), 17–31. doi:10.1016/j.cpr.2005.07.003.

    Article  PubMed  Google Scholar 

  • Carlson, L. E., Speca, M., Faris, P., & Patel, K. D. (2007). One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients. Brain, Behavior, and Immunity, 21(8), 1038–1049. doi:10.1016/j.bbi.2007.04.002.

    Article  PubMed  Google Scholar 

  • Carmody, J., Baer, R. A., Lykins, E. L. B., & Olendzki, N. (2009). An empirical study of the mechanisms of mindfulness in a mindfulness-based stress reduction program. Journal of Clinical Psychology, 65(6), 613–626. doi:10.1002/jclp.20579.

    Article  PubMed  Google Scholar 

  • Chadha, S., Gianotten, W. L., Drogendijk, A. C., Weijmar Schultz, W. C., Blindermen, L. A., & van der Meijden, W. I. (1998). Histopathologic features of vulvar vestibulitis. International Journal of Gynecology and Pathology, 17, 7–11.

    Article  Google Scholar 

  • Clauw, D. J., & Crofford, L. J. (2003). Chronic widespread pain and fibromyalgia: what we know, and what we need to know. Best Practice & Research. Clinical Rheumatology, 17(4), 685–701. doi:10.1016/S1521-6942(03)00035-4.

    Article  Google Scholar 

  • Danielsson, I., Sjoberg, I., Stenlund, H., & Wikman, M. (2003). Dyspareunia in women is common, particularly in younger women: pain history and the women’s age provide valuable clues for diagnosis. [Samlagssmarta hos kvinnor vanligt, inte minst hos yngre. Smartanamnes och kvinnans alder ger god vagledning for diagnos]. Läkartidningen, 100(24), 2128–2132.

    PubMed  Google Scholar 

  • Davidson, R. J., & McEwen, B. S. (2012). Social influences on neuroplasticity: stress and interventions to promote well-being. Nature Neuroscience, 15(5), 689–695. doi:10.1038/nn.3093.

    Article  PubMed Central  PubMed  Google Scholar 

  • Derogatis, L. R., Rosen, R., Leiblum, S., Burnett, A., & Heiman, J. (2002). The Female Sexual Distress Scale (FSDS): initial validation of a standardized scale for assessment of sexually related personal distress in women. Journal of Sex & Marital Therapy, 28(4), 317–330. doi:10.1080/00926230290001448.

    Article  Google Scholar 

  • Desrochers, G., Bergeron, S., Landry, T., & Jodoin, M. (2008). Do psychosexual factors play a role in the etiology of provoked vestibulodynia? A critical review. Journal of Sex & Marital Therapy, 34(3), 198–226.

    Article  Google Scholar 

  • Desrochers, G., Bergeron, S., Khalifé, S., Dupuis, M. J., & Jodoin, M. (2009). Fear avoidance and self-efficacy in relation to pain and sexual impairment in women with provoked vestibulodynia. Clinical Journal of Pain, 25(6), 520–527.

    Article  PubMed  Google Scholar 

  • Desrochers, G., Bergeron, S., Khalifé, S., Dupuis, M., & Jodoin, M. (2010). Provoked vestibulodynia: psychological predictors of topical and cognitive-behavioral treatment outcome. Behaviour Research and Therapy, 48(2), 106–115. doi:10.1016/j.brat.2009.09.014.

    Article  PubMed  Google Scholar 

  • Dworkin, R. H., Turk, D. C., Farrar, J. T., Haythornthwaite, J. A., Jensen, M. P., Katz, N. P., et al. (2005). Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. The Journal of Pain, 113, 9–19.

    Article  Google Scholar 

  • Dworkin, R. H., Turk, D. C., Wyrwich, K. W., Beaton, D., Cleeland, C. S., Farrar, J. T., et al. (2008). Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. The Journal of Pain, 9(2), 105–121.

    Article  PubMed  Google Scholar 

  • Ehrstrom, S., Kornfeld, D., Rylander, E., & Bohm-Starke, N. (2009). Chronic stress in women with localised provoked vulvodynia. Journal of Psychosomatic Obstetrics & Gynecology, 30(1), 73–79. doi:10.1080/01674820802604359.

    Article  Google Scholar 

  • Foster, D. C., Dworkin, R. H., & Wood, R. W. (2005). Effects of intradermal foot and forearm capsaicin injections in normal and vulvodynia-afflicted women. Pain, 117(1), 128–136.

    Article  PubMed  Google Scholar 

  • Foster, D. C., Kotok, M. B., Huang, L. S., Watts, A., Oakes, D., Howard, F. M., et al. (2010). Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial. Obstetrics & Gynecology, 116(3), 583.

    Article  Google Scholar 

  • Fries, E., Hesse, J., Hellhammer, J., & Hellhammer, D. H. (2005). A new view on hypocortisolism. Psychoneuroendocrinology, 30(10), 1010–1016. doi:10.1016/j.psyneuen.2005.04.006.

    Article  PubMed  Google Scholar 

  • Gardner-Nix, J., Backman, S., Barbati, J., & Grummitt, J. (2008). Evaluating distance education of a mindfulness-based meditation programme for chronic pain management. Journal of Telemedicine and Telecare, 14(2), 88–92. doi:10.1258/jtt.2007.070811.

    Article  PubMed  Google Scholar 

  • Gaylord, G. A., Palsson, O. S., Garland, E. L., Faurot, K. R., Coble, R. S., Mann, J. D., et al. (2011). Mindfulness training reduces the severity of irritable bowel syndrome in women: results of a randomized controlled trial. The American Journal of Gastroenterology, 106, 1678–1688.

    Article  PubMed  Google Scholar 

  • Gerber, S., Bongiovanni, A. M., Ledger, W. J., & Witkin, S. S. (2003). Interleukin-1beta gene polymorphism in women with vulvar vestibulitis syndrome. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 107(1), 74–77.

    Article  PubMed  Google Scholar 

  • Giesecke, J., Reed, B. D., Haefner, H. K., Giesecke, T., Clauw, D. J., & Gracely, R. H. (2004). Quantitative sensory testing in vulvodynia patients and increased peripheral pressure pain sensitivity. Obstetrics and Gynecology, 104(1), 126–133. doi:10.1097/01.AOG.0000129238.49397.4e.

    Article  PubMed  Google Scholar 

  • Grant, J. A., Courtemanche, J., & Rainville, P. (2011). A non-elaborative mental stance and decoupling of executive and pain-related cortices predicts low pain sensitivity in zen meditators. Pain, 152(1), 150–156. doi:10.1016/j.pain.2010.10.006.

    Article  PubMed  Google Scholar 

  • Gunter, J. (2007). Vulvodynia: new thoughts on a devastating condition. Obstetrical & Gynecological Survey, 62(12), 812–819. doi:10.1097/01.ogx.0000290350.14036.d6.

    Article  Google Scholar 

  • Harlow, B. L., & Stewart, E. G. (2003). A population-based assessment of chronic unexplained vulvar pain: have we underestimated the prevalence of vulvodynia? Journal of the American Medical Women's Association, 58(2), 82–88.

    PubMed  Google Scholar 

  • Holzel, B. K., Carmody, J., Evans, K. C., Hoge, E. A., Dusek, J. A., Morgan, L., et al. (2010). Stress reduction correlates with structural changes in the amygdale. Social Cognitive Affect Neuroscience, 5, 11–17. doi:10.1093/scan/nsp034.

    Article  Google Scholar 

  • Jantos, M., & Burns, N. R. (2007). Vulvodynia. Development of a psychosexual profile. Journal of Reproductive Medicine, 52(1), 63–71.

    PubMed  Google Scholar 

  • Jantos, M., & White, G. (1997). The vestibulitis syndrome. medical and psychosexual assessment of a cohort of patients. Journal of Reproductive Medicine, 42(3), 145–152.

    PubMed  Google Scholar 

  • Jodoin, M., Bergeron, S., Khalife, S., Dupuis, M. J., Desrochers, G., & Leclerc, B. (2011). Attributions about pain as predictors of psychological symptomatology, sexual function, and dyadic adjustment in women with vestibulodynia. Archives of Sexual Behavior, 40(1), 87–97. doi:10.1007/s10508-010-9647-7.

    Article  PubMed  Google Scholar 

  • Khandker, M., Brady, S. S., Vitonis, A. F., MacLehose, R. F., Stewart, E. G., & Harlow, B. L. (2011). The influence of depression and anxiety on risk of adult onset vulvodynia. Journal of Women's Health, 20(10), 1–7.

    Article  Google Scholar 

  • Komisaruk, B., & Whipple, B. (2000). How does vaginal stimulation produce pleasure, pain, and analgesia. In R. B. Rillingim (Ed.), Sex, gender, and pain (pp. 109–134). Seattle: IASP Press.

    Google Scholar 

  • Koyama, T., McHaffie, J. G., Laurienti, P. J., Coghill, R. C., & Smith, E. E. (2005). The subjective experience of pain: where expectations become reality. Proceedings of the National Academy of Sciences of the United States of America, 102(36), 12950–12955.

    Article  PubMed Central  PubMed  Google Scholar 

  • Landry, T., Bergeron, S., Dupuis, M. J., & Desrochers, G. (2008). The treatment of provoked vestibulodynia: a critical review. The Clinical Journal of Pain, 24(2), 155–171.

    Article  PubMed  Google Scholar 

  • Lau, M. A., & McMain, S. F. (2005). Integrating mindfulness meditation with cognitive and behavioural therapies: the challenge of combining acceptance- and change-based strategies. Canadian Journal of Psychiatry, 50(13), 863–869.

    Google Scholar 

  • Leeuw, M., Goossens, M. E., Linton, S. J., Crombez, G., Boersma, K., & Vlaeyen, J. W. (2007). The fear-avoidance model of musculoskeletal pain: current state of scientific evidence. Journal of Behavioral Medicine, 30(1), 77–94. doi:10.1007/s10865-006-9085-0.

    Article  PubMed  Google Scholar 

  • Lorig, K., Chastain, R. L., Ung, E., Shoor, S., & Holman, H. R. (1989). Development and evaluation of a scale to measure perceived self-efficacy in people with arthritis. Arthritis and Rheumatism, 32(1), 37–44.

    Article  PubMed  Google Scholar 

  • Ludwig, D. S., & Kabat-Zinn, J. (2008). Mindfulness in medicine. Journal of the American Medical Association, 300(11), 1350–1352. doi:10.1001/jama.300.11.1350.

    Article  PubMed  Google Scholar 

  • Ma, S. H., & Teasdale, J. D. (2004). Mindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects. Journal of Consulting and Clinical Psychology, 72(1), 31–40.

    Article  PubMed  Google Scholar 

  • Masheb, R. M., Kerns, R. D., Lozano, C., Minkin, M. J., & Richman, S. (2009). A randomized clinical trial for women with vulvodynia: cognitive-behavioral therapy vs. supportive psychotherapy. Pain, 141(1–2), 31–40. doi:10.1016/j.pain.2008.09.031.

    Article  PubMed Central  PubMed  Google Scholar 

  • Matousek, R. H., & Dobkin, P. L. (2010). Weathering storms: a cohort study of how participation in a mindfulness-based stress reduction program benefits women after breast cancer treatment. Current Oncology, 17(4), 62–70.

    PubMed Central  PubMed  Google Scholar 

  • McCracken, L. M. (1997). Attention to pain in persons with chronic pain: a behavioral approach. Behavior Therapy, 28(2), 271–284.

    Article  Google Scholar 

  • McCracken, L. M., & Eccleston, C. (2005). A prospective study of acceptance of pain and patient functioning with chronic pain. Pain, 118, 164–169.

    Article  PubMed  Google Scholar 

  • McCracken, L. M., Gauntlett-Gilbert, J., & Vowles, K. E. (2007). The role of mindfulness in a contextual cognitive-behavioral analysis of chronic pain-related suffering and disability. Pain, 131, 63–69.

    Article  PubMed  Google Scholar 

  • Nelson, A. L., & Purdon, C. (2011). Non-erotic thoughts, attentional focus, and sexual problems in a community sample. Archives of Sexual Behavior, 40, 395–406.

    Article  PubMed  Google Scholar 

  • Nguyen, R. H., MacLehose, R. F., Veasley, C., Turner, R. M., Harlow, B. L., & Horvath, K. J. (2012). Comfort in discussing vulvar pain in social relationships among women with vulvodynia. Journal of Reproductive Medicine, 57(3–4), 109–114.

    PubMed  Google Scholar 

  • Norton, P. J., & Asmundson, G. J. G. (2003). Amending the fear-avoidance model of chronic pain: what is the role of physiological arousal? Behaviour Therapy, 34(1), 17–30.

    Article  Google Scholar 

  • Nyirjesy, P., Sobel, J. D., Weitz, M. V., Leaman, D. J., Small, M. J., & Gelone, S. P. (2001). Cromolyn cream for recalcitrant idiopathic vulvar vestibulitis: results of a placebo controlled study. Sexually Transmitted Infections, 77(1), 53–57. doi:10.1136/sti.77.1.53.

    Article  PubMed Central  PubMed  Google Scholar 

  • Payne, K. A., Binik, Y. M., Amsel, R., & Khalifé, S. (2005). When sex hurts, anxiety and fear orient attention towards pain. European Journal of Pain, 9, 427–436.

    Article  PubMed  Google Scholar 

  • Perlman, D. M., Salomons, T. V., Davidson, R. J., & Lutz, A. (2010). Differential effects on pain intensity and unpleasantness of two meditation practices. Emotion, 10(1), 65–71. doi:10.1037/a0018440.

    Article  PubMed Central  PubMed  Google Scholar 

  • Reed, B. D., Harlow, S. D., Sen, A., Edwards, R. M., Chen, D., & Haefner, H. K. (2012a). Relationship between vulvodynia and chronic comorbid pain conditions. Obstetrics and Gynecology, 120, 145–151.

    Article  PubMed Central  PubMed  Google Scholar 

  • Reed, B. D., Harlow, S. D., Sen, A., Legocki, L. J., Edwards, R. M., Arato, N., et al. (2012b). Prevalence and demographic characteristics of vulvodynia in a population-based sample. American Journal of Obstetrics and Gynecology, 206, 170.e1–170.e9.

    Article  Google Scholar 

  • Roelofs, J., Peters, M. L., McCracken, L., & Vlaeyen, J. W. (2003). The Pain Vigilance and Awareness Questionnaire (PVAQ): further psychometric evaluation in fibromyalgia and other chronic pain syndromes. Pain, 101(3), 299–306.

    Article  PubMed  Google Scholar 

  • Roemer, L., & Orsillo, S. M. (2002). Expanding our conceptualization of and treatment for generalized anxiety disorder: integrating mindfulness/acceptance-based approaches with existing cognitive-behavioral models. Clinical Psychology: Science and Practice, 9, 54–68.

    Google Scholar 

  • Rosen, R., Brown, C., Heiman, J., Leiblum, S., Meston, C., Shabsigh, R., et al. (2000). The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. Journal of Sex and Marital Therapy, 26(2), 191–208. doi:10.1080/009262300278597.

    Article  PubMed  Google Scholar 

  • Rosenbaum, T. Y. (2013). An integrated mindfulness-based approach to the treatment of women with sexual pain and anxiety: promoting autonomy and mind/body connection. Sexual and Relationship Therapy, 28, 20–28.

    Article  Google Scholar 

  • Schutze, R., Rees, C., Preece, M., & Schutze, M. (2010). Low mindfulness predicts pain catastrophizing in a fear-avoidance model of chronic pain. Pain, 148(1), 120–127. doi:10.1016/j.pain.2009.10.030.

    Article  PubMed  Google Scholar 

  • Schweinhardt, P., Kuchinad, A., Pukall, C. F., & Bushnell, M. C. (2008). Increased gray matter density in young women with chronic vulvar pain. Pain, 140(3), 411–419.

    Article  PubMed  Google Scholar 

  • Soderman, A. R., & Unterwald, E. M. (2008). Cocaine reward and hyperactivity in the rat: sites of mu opioid receptor modulation. Neuroscience, 154(4), 1506–1516. doi:10.1016/j.neuroscience.2008.04.063.

    Article  PubMed Central  PubMed  Google Scholar 

  • Spielberger, C. D., Gorsuch, R. L., Lushene, R., Vagg, P. R., & Jacobs, G. A. (1983). State trait anxiety inventory for adults manual. Palo Alto, CA: Consulting Psychologists Press.

    Google Scholar 

  • Spoelstra, S. K., Dijkstra, J. R., van Driel, M. F., & Weijmar Schultz, W. C. (2011). Long-term results of an individualized, multifaceted, and multidisciplinary therapeutic approach to provoked vestibulodynia. Journal of Sexual Medicine, 8(2), 489–496. doi:10.1111/j.1743-6109.2010.01941.x.

    Article  PubMed  Google Scholar 

  • Sullivan, M. J. L., Bishop, S. R., & Pivik, J. (1995). The pain catastrophizing scale: development and validation. Psychological Assessment, 7(4), 524–532. doi:10.1037/1040-3590.7.4.524.

    Article  Google Scholar 

  • Sutton, K. S., Pukall, C. F., & Chamberlain, S. (2009a). Pain ratings, sensory thresholds, and psychosocial functioning in women with provoked vestibulodynia. Journal of Sex & Marital Therapy, 35(4), 262–281.

    Article  Google Scholar 

  • Sutton, K. S., Pukall, C. F., & Chamberlain, S. (2009b). Pain, psychosocial, sexual, and psychophysical characteristics of women with primary vs. secondary provoked vestibulodynia. Journal of Sexual Medicine, 6(1), 205–214. doi:10.1111/j.1743-6109.2008.01038.x.

    Article  PubMed  Google Scholar 

  • Teasdale, J. D., Segal, Z., & Williams, J. M. (1995). How does cognitive therapy prevent depressive relapse and why should attentional control (mindfulness) training help? Behaviour Research and Therapy, 33(1), 25–39.

    Article  PubMed  Google Scholar 

  • Theoharides, T. C., Donelan, J. M., Papadopoulou, N., Cao, J., Kempuraj, D., & Conti, P. (2004). Mast cells as targets of corticotrophin-releasing factor and related peptides. Trends in Pharmacological Sciences, 25, 563–568.

    Article  PubMed  Google Scholar 

  • Tommola, P., Unkila-Kallio, L., & Paavonen, J. (2010). Surgical treatment of vulvar vestibulitis: a review. Acta Obstetricia Et Gynecologica Scandinavica, 89(11), 1385–1395. doi:10.3109/00016349.2010.512071.

    Article  PubMed  Google Scholar 

  • Tracey, I., & Bushnell, M. C. (2009). How neuroimaging studies have challenged us to rethink: is chronic pain a disease? The Journal of Pain, 10(11), 1113–1120. doi:10.1016/j.jpain.2009.09.001.

    Article  PubMed  Google Scholar 

  • Trudel, G., Marchand, A., Ravart, M., Aubin, S., Turgeon, L., & Fortier, P. (2001). The effect of a cognitive-behavioral group treatment program on hypoactive sexual desire in women. Sexual and Relationship Therapy, 16(2), 145–164. doi:10.1080/14681990120040078.

    Article  Google Scholar 

  • Ussher, M., Spatz, A., Copland, C., Nicolaou, A., Cargill, A., Amini-Tabrizi, N., et al. (2012). Immediate effects of a brief mindfulness-based body scan on patients with chronic pain. Journal of Behavioral Medicine. doi:10.1007/s10865-012-9466-5.

    PubMed  Google Scholar 

  • Vachon-Presseau, E., Roy, M., Martel, M. O., & Caron, E. (2013). The stress model of chronic pain: evidence from basal cortisol and hippocampal structure and function in humans. Brain: A Journal of Neurology, 136, 815–827. doi:10.1093/brain/aws371.

    Article  Google Scholar 

  • van der Vegt, E. J., van der Ende, J., Kirschbaum, C., Verhulst, F. C., & Tiemeier, H. (2009). Early neglect and abuse predict diurnal cortisol patterns in adults: a study of international adoptees. Psychoneuroendocrinology, 34(5), 660–669. doi:10.1016/j.psyneuen.2008.11.004.

    Article  PubMed  Google Scholar 

  • van Lankveld, J. J., Granot, M., Weijmar Schultz, W. C., Binik, Y. M., Wesselmann, U., Pukall, C. F., et al. (2010). Women’s sexual pain disorders. Journal of Sexual Medicine, 7, 615–631.

    Article  PubMed  Google Scholar 

  • Vlaeyen, J. W., de Jong, J., Geilen, M., Heuts, P. H., & van Breukelen, G. (2001). Graded exposure in vivo in the treatment of pain-related fear: a replicated single-case experimental design in four patients with chronic low back pain. Behaviour Research and Therapy, 39(2), 151–166.

    Article  PubMed  Google Scholar 

  • Vlaeyen, J. W., de Jong, J. R., Onghena, P., Kerckhoffs-Hanssen, M., & Kole-Snijders, A. M. (2002). Can pain-related fear be reduced? The application of cognitive-behavioural exposure in vivo. Pain Research & Management, 7(3), 144–153.

    Google Scholar 

  • Woolf, C. J. (2011). Central sensitization: implications for the diagnosis and treatment of pain. Pain, 152(3), S2–S15. doi:10.1016/j.pain.2010.09.030.

    Article  PubMed Central  PubMed  Google Scholar 

  • Zeidan, F., Gordon, N. S., Merchant, J., & Goolkasian, P. (2010). The effects of brief mindfulness meditation training on experimentally induced pain. The Journal of Pain, 3, 199–209.

    Article  Google Scholar 

  • Zeidan, F., Grant, J. A., Brown, C. A., McHaffie, J. G., & Coghill, R. C. (2012). Mindfulness meditation-related pain relief: evidence for unique brain mechanisms in the regulation of pain. Neuroscience Letters, 520(2), 165–173. doi:10.1016/j.neulet.2012.03.082.

    Article  PubMed Central  PubMed  Google Scholar 

Download references

Acknowledgments

The authors wish to thank Robyn Jackowich, Melissa Moses, Miranda Abild, and Pretty Verma for assistance carrying out the study. We also wish to thank group facilitators Marie Carlson, Kate McBride, and Dr. Gail Knudson. We thank Dr. Sydney Thomson and Dr. Mijla Luria for input during the initial design of this study. Funding for this study was provided from a Women’s Health Research Institute Grant to L.A.B. K.B.S. is currently supported by a Post Doctoral Clinical Research Trainee Award from the Michael Smith Foundation for Health Research and a Post Doctoral Fellowship Award from the Canadian Pain Society.

Conflict of Interest

None of the authors have any conflicts of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lori A. Brotto.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Brotto, L.A., Basson, R., Smith, K.B. et al. Mindfulness-based Group Therapy for Women with Provoked Vestibulodynia. Mindfulness 6, 417–432 (2015). https://doi.org/10.1007/s12671-013-0273-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12671-013-0273-z

Keywords

Navigation