Abstract
Symptoms of Autism Spectrum Disorders (ASD) begin to manifest during the first 2 years; there is limited evidence regarding type and timing of symptom onset. We examined factors related to parental age of recognition (AOR) of early abnormalities and the association between AOR and diagnosis and levels of functioning at 2 and 4 years in 75 toddlers with ASD. Results suggest significant differences between autism and PDD-NOS in the AOR and type of first concerns. Early social and motor delays as well as maternal age was associated with AOR. Later AOR was associated with poorer social-communicative and nonverbal cognitive functioning at 2 and 4. The findings are discussed in a context of identifying distinct developmental trajectories within the autism spectrum.
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References
American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (4th ed., DSM-IV). Washington, DC: Author.
Baghdadli, A., Picot, M. C., Pascal, C., Pry, R., & Aussilloux, C. (2003). Relationship between age of recognition of first disturbances and severity in young children with autism. European Child & Adolescent Psychiatry, 12(3), 122–127.
Bloom, L. (1997). Language acquisition in its developmental context. In D. Khun & R. Siegler (Eds.), Cognition, perception, and language (Vol. 2). In W. Damo (series Ed.), Handbook of child psychology (pp 255–298). NY: John Wiley & Sons.
Chawarska, K., Klin, A., Paul, R., & Volkmar, F. R. (2007). Autism spectrum disorder in the second year: Stability and change in syndrome expression. Journal of Child Psychology and Psychiatry, in press.
Chawarska, K., & Volkmar, F. R. (2005). Autism in infancy and early childhood. In: F. R. Volkmar, R. Paul, A. Klin, & D. Cohen (eds.), Handbook of autism and pervasive developmental disorders, Vol. 1: Diagnosis, development, neurobiology, and behavior (3rd ed.).
Christopher, J. A., Sears, L. L., Williams, P. G., Oliver, J., & Hersh, J. (2004). Familial, medical and developmental patterns of children with autism and a history of language regression. Journal of Developmental & Physical Disabilities, 16(2), 163–170.
Cooper, J., Kim, P., Taylor, A., & Lord, C. (2001). Early communication and social skills in children with autism spectrum disorders, with and without early word loss. Paper presented at the International Meeting for Autism Research (IMFAR). San Diego, CA.
Courage, M. L., & Howe, M. L. (2002). From infant to child: The dynamics of cognitive change in the second year of life. Psychological Bulletin, 128(2), 250–277.
Croen, L. A., Grether, J. K., & Selvin, S. (2002). Descriptive epidemiology of autism in a California population: who is at risk?. Journal of Autism and Developmental Disorders, 32(3), 217–224.
Davidovitch, M., Glick, L., Holtzman, G., Tirosh, E., & Safir, M. P. (2000). Developmental regression in autism: Maternal perception. Journal of Autism and Developmental Disorders, 30(2), 113–119.
De Giacomo, A., & Fombonne, E. (1998). Parental recognition of developmental abnormalities in autism. European Child & Adolescent Psychiatry, 7(3), 131–136.
Gillberg, C., Ehlers, S., Schaumann, H., Jakobbson, G., Dahlgren, S. O., Lindblom, R., Bagenholm, A., Tjuus, T., & Blidner, E. (1990). Autism under age 3 years: A clinical study of 28 cases referred for autistic symptoms in infancy. Journal of Child Psychology & Psychiatry & Allied Disciplines, 31(6), 921–934.
Glasson, E. J., Bower, C., Petterson, B., de Klerk, N., Chaney, G., & Hallmayer, J. F. (2004). Perinatal factors and the development of autism: A population study. Archives of General Psychiatry, 61(6), 618–627.
Goldberg, W. A., Osann, K., Filipek, P. A., Laulhere, T., Jarvis, K., Modahl, C., Flodman, P., & Spence, M. A. (2003). Language and other regression: Assessment and timing. Journal of Autism and Developmental Disorders, 33(6), 607–616.
Hoshino, Y., Kaneko, M., Yashima, Y., Kumashiro, H., Volkmar, F. R., & Cohen, D. J. (1987). Clinical features of autistic children with setback course in their infancy. Japanese Journal of Psychiatry & Neurology, 41(2), 237–245.
Klin, A., Chawarska, K., Paul, R., Rubin, E., Morgan, T., Wiesner, L., & Volkmar, F. (2004). Autism in a 15-month-old child. American Journal of Psychiatry, 161(11), 1981–1988.
Klin, A., Chawarska, K., Rubin, E., & Volkmar, F. (2003). Clinical assessment of young children at risk for autism. In R. DelCarment-Wiggins & A. Carter (Eds.), Handbook of infant and toddler mental health assessment. New York, NY: Oxford University Press.
Kurita, H. (1985). Infantile autism with speech loss before the age of thirty months. Journal of the American Academy of Child Psychiatry, 24(2), 191–196.
Lord, C., Risi, S., Lambrecht, L., Cook Jr., E. H., Leventhal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000). The Autism diagnostic observation schedule–generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.
Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview–revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24(5), 659–685.
Lord, C., Shulman, C., & DiLavore, P. (2004). Regression and word loss in autistic spectrum disorders. Journal of Child Psychology & Psychiatry, 45(5), 936–955.
Luyster, R., Richler, J., Risi, S., Hsu, W., Dawson, G., Bernier, R., Dunn, M., Hepburn, S., Hyman, S. L., McMahon, W. M., Goudie-Nice, J., Minshew, N., Rogers, S., Sigman, M., Spence, M. A., Goldberg, W. A., Tager-Flusberg, H., Volkmar, F. R., & Lord, C. (2005). Early regression in social communication in autism spectrum disorders: A CPEA study. Developmental Neuropsychology, 27(3), 311–336.
Mullen, E. (1995). Mullen scales of early learning. AGS edition. Circle Pines, MN: American Guidance Serivce, Inc.
Oller, D. K., Levine, S., Cobo-Lewis, A., Eilers, R., & Pearson, B. (1998). Vocal precursors to linguistic communication: How babbling is connected to meaningful speech. In R. Paul (Ed.), Exploring the speech-language connection (pp 1–23). Baltimore, MD: Brookes.
Rapin, I., & Katzman, R. (1998). Neurobiology of autism. Annals of Neurology, 43(1), 7–14.
Rogers, S. J., & DiLalla, D. L. (1990). Age of symptom onset in young children with pervasive developmental disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 29(6), 863–872.
Rutter, M. (2005). Environmentally mediated risks for psychopathology: Research strategies and findings. Journal of the American Academy of Child & Adolescent Psychiatry, 44(1), 3–18.
Short, A. B., & Schopler, E. (1988). Factors relating to age of onset in autism. Journal of Autism and Developmental Disorders, 18(2), 207–216.
Siperstein, R., & Volkmar, F. (2004). Brief report: Parental reporting of regression in children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 34(6), 731–734.
Sparrow, S. S., Balla, D. A., & Cicchetti, D. V. (1984). Vineland adaptive behavior scales: Interview edition, survey form manual. Circle Pines, Minn: American Guidance Service.
Tolbert, L., Brown, R., Fowler, P., & Parsons, D. (2001). Brief report: Lack of correlation between age of symptom onset and contemporaneous presentation. Journal of Autism and Developmental Disorders, 31(2), 241–245.
Tuchman, R. F., & Rapin, I. (1997). Regression in pervasive developmental disorders: seizures and epileptiform electroencephalogram correlates. Pediatrics, 99(4), 560–566.
Wilson, S., Djukie, A., Shinnar, S., Dharmani, C., & Rapin, I. (2003). Clinical characteristics of language regression in children. Developmental Medicine and Child Neurology. 45, 508–514.
Volkmar , F. R., Klin, A., Siegel, B., Szatmari, P., Lord, C., Campbell, M., Freeman, B. J., Cicchetti, D. V., Rutter, M., & Kline, W. (1994). Field trial for autistic disorder in DSM-IV. American Journal of Psychiatry, 151, 1361–1367.
Volkmar, F. R., Koenig, K., & State, M. (2005). Childhood disintegrative disorder. In: F. R. Volkmar, R. Paul, A. Klin, & D. Cohen (Eds.), Handbook of autism and pervasive developmental disorders, Vol. 1: Diagnosis, development, neurobiology, and behavior (3rd ed., pp 70–87). Hoboken, NJ: John Wiley & Sons, Inc.
Volkmar, F. R., Stier, D. M., & Cohen, D. J. (1985). Age of recognition of pervasive developmental disorder. American Journal of Psychiatry, 142(12), 1450–1452.
Werner, E., & Dawson, G. (2005). Validation of the phenomenon of autistic regression using home videotapes. Archives of General Psychiatry, 62(8), 889–895.
Werner, E., Dawson, G. Munson, J., & Osterling, J. (2005). Variation in early developmental course in autism and its relation with behavioral outcome at 3–4 years of age. Journal of Autism and Developmental Disorders, 35(3), 337–350.
Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J., & Szatmari, P. (2005). Behavioral manifestations of autism in the first year of life. International Journal of Developmental Neuroscience, 23(2–3), 143–152.
Acknowledgments
This study was supported by the NAAR grants and NIMH Grant # U54 MH66494 awarded to Fred Volkmar, Katarzyna Chawarska, Ami Klin, and Rhea Paul. We would like to thank the children and their parents who participated in the study.
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Chawarska, K., Paul, R., Klin, A. et al. Parental Recognition of Developmental Problems in Toddlers with Autism Spectrum Disorders. J Autism Dev Disord 37, 62–72 (2007). https://doi.org/10.1007/s10803-006-0330-8
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DOI: https://doi.org/10.1007/s10803-006-0330-8