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Recurrent vestibulopathy: are cVEMP, oVEMP and inner ear MRI useful to distinguish patients with Menière’s disease and vestibular migraine?

  • Otology
  • Published:
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Abstract

Purpose

The aim of this study was to assess the rate of endolymphatic hydrops (EH) on MRI and the rate of otolithic dysfunction with cVEMP and oVEMP, in patients with recurrent vertigo such as Menière’s disease (MD), vestibular migraine (VM) and vestibular Menière’s disease (vMD).

Methods

In this retrospective study, we performed 3D-FLAIR sequences with delayed acquisition in 20 MD, 20 VM and 20 vMD patients. Each subject was then assessed for the presence of EH on MRI. All patients underwent pure-tone audiometry, cVEMP and oVEMP.

Results

In MD patients, EH was observed in 18 (90%) out of 20 patients while EH was observed in only 1 MV (5%) and 1 vMD (5%) patients. We found significant differences between groups for the presence of EH on MRI (p = 0.001). MD patients had significant higher PTA level (p < 0.001) and oVEMP impairment than MV and vMD (p = 0.08 and p = 0.06, respectively). However, no significant differences were observed for cVEMP impairment, either asymmetric ratio (p = 0.36) and 1000/500 ratio (p = 0.20).

Conclusions

Concerning cVEMP, we observed no significant differences between VM, vMD and MD. However, we observed higher oVEMP impairment, PTA level and EH on MRI in MD patients. We believe that MRI could be used to differentiate MD from VM patients with cochlear symptoms. However, in cases of migraine associated with recurrent vertigo and without cochlear symptoms, we believe that MRI is not a useful tool to differentiate between VM and vMD.

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Acknowledgements

We thank Pamela Haylock (Lariboisiere University Hospital) for critically editing the manuscript.

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Authors and Affiliations

  1. Neuroradiology Unit, Department of Neuroradiology, Lariboisière University Hospital, 75010, Paris, France

    Michael Eliezer & Emmanuel Houdart

  2. Centre D’Explorations Fonctionnelles Otoneurologiques, Paris, France

    Michel Toupet

  3. Department of Head and Neck Surgery, Lariboisière University Hospital, Paris, France

    Juliette Housset & Charlotte Hautefort

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  1. Michael Eliezer
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Correspondence to Michael Eliezer.

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Eliezer, M., Toupet, M., Housset, J. et al. Recurrent vestibulopathy: are cVEMP, oVEMP and inner ear MRI useful to distinguish patients with Menière’s disease and vestibular migraine?. Eur Arch Otorhinolaryngol 279, 713–721 (2022). https://doi.org/10.1007/s00405-021-06716-6

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