Six years have passed since the spring of 2018, the inception date of SN Comprehensive Clinical Medicine (SNCCM), which then accepted its first submissions in July 2018 and began publication in early 2019. Entering such a crowded field, such as that of mega journals, was a courageous choice, a significant challenge, based on the desire to offer a global platform for sound science, open to both the North Globe and the South Globe, with a primary focus on the educational aspect. The journal, in its hybrid format, allows equity of access both to publication and to content reading. From the outset, the submission flow has been significant, then very exuberant, quasi torrential, during the pandemic period, then returning to recent values showing a steady growth both quantitatively and qualitatively. The remodeling of the Editorial Board with renowned global experts has not overlooked the integration of many young talents, allowing for detailed coverage of all medical, surgical, and their respective subspecialties. The journal metrics are progressively increasing, turnaround times are greatly reduced (12 days on average for the initial decision and around 350,000 downloads in 2023), and the attention of the various boards is now focused on maintaining a balance that does not disadvantage regions with suboptimal access to clinical research. To date, 1,644 articles have been published with over 8,000 citations, averaging about 5 citations per article (Source: Dimensions, March 24, 2024). SNCCM aims to respond to strong pushes for access that originate not only from the mega Asian regions but also from earlier-stage regional realities that still express a strong need for growth. A strategic aim of SNCCM is to contribute to the reduction of disparity in medical care as included in the United Nations Sustainable Development Goals programs (3 and 5) focused on Health and Population. This aim to provide sound science evidence is very targeted in favor of individuals living health problems, especially those with a disadvantage for access to innovative treatments because of socio-cultural, macroeconomic, and national registration reasons. In conclusion, this examination, which is SNCCM's first venture outside its own pages, aims to offer the reading of this passage as an indicator of the willingness to grow and cooperatively engage with the entire scientific community of Clinical Medicine.

Paolo Martelletti, MD, Professor Unitelma Sapienza University, Rome, Italy

Editor in Chief SN Comprehensive Clinical Medicine

Rome, 24 March 2024