Oral Manifestations in Systemic Infections Oral manifestations can be observed in almost every generalized systemic infectious disease. Only the most characteristic ones are illustrated on this page. Measles produces a pathognomonic eruption of the mouth in the prodromal stage before any cutaneous lesions have become evident. About the second day after the first signs of the disease (coryza, conjunctivitis, and fever) become evident, the palate and fauces become intensely red, and the…