Ubi pus, ibi evacua: Optimizing intrapleural fibrinolytic therapy in pleural infections
- PMID: 35560748
- DOI: 10.1111/resp.14293
Ubi pus, ibi evacua: Optimizing intrapleural fibrinolytic therapy in pleural infections
Keywords: deoxyribonuclease; empyema; intrapleural fibrinolytic therapy; pleural effusion; pleural infection; tissue plasminogen activator.
Comment on
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Alteplase Dose Assessment for Pleural infection Therapy (ADAPT) Study-2: Use of 2.5 mg alteplase as a starting intrapleural dose.Respirology. 2022 Jul;27(7):510-516. doi: 10.1111/resp.14261. Epub 2022 Apr 19. Respirology. 2022. PMID: 35441458
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References
REFERENCES
-
- Tillett WS, Sherry S. The effect in patients of streptococcal fibrinolysin (streptokinase) and streptococcal desoxyribonuclease on fibrinous, purulent, and sanguinous pleural exudations. J Clin Invest. 1949;28(1):173-90.
-
- Altmann ES, Crossingham I, Wilson S, Davies HR. Intra-pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult parapneumonic effusions and empyema. Cochrane Database Syst Rev. 2019;(10):CD002312.
-
- Lau EPM, Eshraghi M, Dootson K, Yeoh C, Ywe Phu W, Lee YCG, et al. An international survey on the use of intrapleural tissue plasminogen activator/DNase therapy for pleural infection. ERJ Open Res. 2022;8(1):00590-2021.
-
- Scarci M, Abah U, Solli P, Page A, Waller D, van Schil P, et al. EACTS expert consensus statement for surgical management of pleural empyema. Eur J Cardiothorac Surg. 2015;48(5):642-53.
-
- Chaddha U, Agrawal A, Feller-Kopman D, Kaul V, Shojaee S, Maldonado F, et al. Use of fibrinolytics and deoxyribonuclease in adult patients with pleural empyema: a consensus statement. Lancet Respir Med. 2021;9(9):1050-64.
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