Epidemiology of childhood cancer
- PMID: 20231056
- DOI: 10.1016/j.ctrv.2010.02.003
Epidemiology of childhood cancer
Abstract
The present contribution reports childhood cancer incidence and survival rates as well as time trends and geographical variation. The report is based on the databases of population-based cancer registries which joined forces in cooperative projects such as Automated Childhood Cancer Information System (ACCIS) and EUROCARE. According to these data, which refer to the International Classification of Childhood Cancer, leukemias, at 34%, brain tumors, at 23%, and lymphomas, at 12%, represent the largest diagnostic groups among the under 15-year-olds. The most frequent single diagnoses are: acute lymphoblastic leukemia, astrocytoma, neuroblastoma, non-Hodgkin lymphoma, and nephroblastoma. There is considerable variation between countries. Incidence rates range from 130 (British Isles) to 160 cases (Scandinavian countries) per million children. Incidence rates have shown an increase over time since the mid of the last century. In Europe, the yearly increase averages 1.1% for the 1978-1997 period and ranges from 0.6% for the leukemias to 1.8% for soft-tissue sarcomas. The probability of survival has risen considerably over the past decades, with the EUROCARE data showing an improvement of the relative risk of death by 8% when comparing the 2000-2002 time span to the 1995-1999 period. Regarding the years 1995-2002, the data show an overall 5-year survival probability of 81% for Europe and similar values for the USA. The data presented here describe the cancer situation with a specific, European focus. They are drawn from population-based cancer registries that ensure excellent data quality, and as a consequence represent the most valid European population-based data existing at present. It is also apparent that not all countries have data available from nationwide childhood cancer registries, a situation which warrants further improvement.
2010 Elsevier Ltd. All rights reserved.
Similar articles
-
Epidemiology of childhood cancer in India.Indian J Cancer. 2009 Oct-Dec;46(4):264-73. doi: 10.4103/0019-509X.55546. Indian J Cancer. 2009. PMID: 19749456 Review.
-
Neuroblastoma incidence and survival in European children (1978-1997): report from the Automated Childhood Cancer Information System project.Eur J Cancer. 2006 Sep;42(13):2081-91. doi: 10.1016/j.ejca.2006.05.008. Eur J Cancer. 2006. PMID: 16919772
-
Quality, comparability and methods of analysis of data on childhood cancer in Europe (1978-1997): report from the Automated Childhood Cancer Information System project.Eur J Cancer. 2006 Sep;42(13):1915-51. doi: 10.1016/j.ejca.2006.05.007. Eur J Cancer. 2006. PMID: 16919762 Review.
-
[Lorraine childhood cancer registry: incidence, survival 1983-1999].Arch Pediatr. 2005 Nov;12(11):1577-86. doi: 10.1016/j.arcped.2005.06.010. Epub 2005 Aug 11. Arch Pediatr. 2005. PMID: 16099145 French.
-
Childhood cancer survival trends in Europe: a EUROCARE Working Group study.J Clin Oncol. 2005 Jun 1;23(16):3742-51. doi: 10.1200/JCO.2005.00.554. J Clin Oncol. 2005. PMID: 15923571
Cited by
-
B-NHL Cases in a Tertiary Pediatric Hematology-Oncology Department: A 20-Year Retrospective Cohort Study.Life (Basel). 2024 May 16;14(5):633. doi: 10.3390/life14050633. Life (Basel). 2024. PMID: 38792653 Free PMC article.
-
Incidence of Pediatric Cancers in French Guiana: How Does It Compare to Global Estimates?Cancers (Basel). 2024 May 10;16(10):1829. doi: 10.3390/cancers16101829. Cancers (Basel). 2024. PMID: 38791908 Free PMC article.
-
Development and validation of a prognostic nomogram for patients with ganglioneuroblastoma: A SEER-based study.Heliyon. 2024 May 8;10(9):e30891. doi: 10.1016/j.heliyon.2024.e30891. eCollection 2024 May 15. Heliyon. 2024. PMID: 38774105 Free PMC article.
-
Reintegration into school, kindergarten and work in families of childhood cancer survivors after a family-oriented rehabilitation program.Front Pediatr. 2024 Mar 7;12:1288567. doi: 10.3389/fped.2024.1288567. eCollection 2024. Front Pediatr. 2024. PMID: 38516352 Free PMC article.
-
Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study.PLoS One. 2024 Feb 16;19(2):e0298068. doi: 10.1371/journal.pone.0298068. eCollection 2024. PLoS One. 2024. PMID: 38363727 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous