Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. See the Portfolio User Guide.

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year PCORI approved the research study or project for funding. View Glossary
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Displaying 1 - 25 of 222 results

Project Title
Project Status
Funding Type

Improving the Quality of Care for Asthma Patients at Risk of Exacerbations, i-CARE

Brigham and Women's Hospital
| Massachusetts
Elliot Israel, M.D.
Project Status:
Awarded; In progress
Funding Type:
Research

A Comparative Effectiveness Study of Oral Medications Used for Migraine Prevention

Mayo Clinic Arizona
| Arizona
Todd Schwedt, B.S., M.D., M.S.
Project Status:
Awarded; In progress
Funding Type:
Research

Balanced Subgroup Discovery: Who Benefits Most From an Intervention?

Wake Forest University
| North Carolina
Joseph Rigdon, B.S., M.S., Ph.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Improving High Blood Pressure in Older Adults Living with Multiple Chronic Diseases - The SMBP Study

The University of Iowa College of Pharmacy
| Iowa
Korey Kennelty, M.S., Ph.D., Phrm.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Improving In-Hospital Sleep Hygiene to Prevent and Curtail Delirium Among Older Adults

The Methodist Hospital Research Institute
| Texas
Farhaan Vahidy, Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

The SCOPE Trial: Sleep, Cognition, and Pain Bundle Versus Enhanced Recovery After Surgery-Cardiac for Postoperative Delirium

Beth Israel Deaconess Medical Center
| Massachusetts
Balachundhar Subramaniam, M.D., MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Implementation and Interaction of Clinician and Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure With Reduced Ejection Fraction

University of Colorado Denver
| Colorado
Larry Allen, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Home-Based Pulmonary Rehabilitation With Health Coaching in Patients With Fibrotic Lung Disease

Mayo Clinic Rochester
| Minnesota
Teng Moua, M.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Improving Outcomes for Patients with Multiple Chronic Conditions Using ECHO

University of New Mexico Health Sciences Center
| New Mexico
Sanjeev Arora, M.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Reducing Future Fractures and Improving Outcomes of Fragility Fracture -- The RESTORE Study

The University of Alabama at Birmingham
| Alabama
Kenneth Saag, M.D., M.Sc.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Comorbidity of Chronic Pain and Early Cognitive Decline Among Older, Community-Based Black Adults: Comparative Effectiveness of Mindfulness-Based Cognitive Therapy with walking (MBCT) versus Active Living Every Day (ALED)

Massachusetts General Hospital
| Massachusetts
Olivia Okereke, A.B., M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Models of Post-Acute Care in Complex Older Adults with Fracture

Duke University School of Medicine
| North Carolina
Cathleen Colon-Emeric, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Activating SilverSneakers Benefits for Seniors with Osteoarthritis: Proactive versus Usual Care

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Liza Rovniak, Ph.D., MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research, Research Conducted Using PCORnet®

Annual Wellness Visits versus GRACE-augmented Annual Wellness Visits for Older Adults with High Needs

Massachusetts General Hospital
| Massachusetts
Christine Ritchie, M.D., MSPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Generalist versus Specialist Palliative Care for Inpatients

University of Pennsylvania
| Pennsylvania
Scott Halpern, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Comparative Effectiveness of Lifestyle Interventions for Older Cancer Survivors and Their Caregivers

Dana-Farber Cancer Institute
| Massachusetts
Christina Dieli-Conwright, Ph.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Comparing Oral Drug Dosing Strategies in Older Patients with Metastatic Breast Cancer to Maximize Tolerance and Reduce Discontinuation: The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

American Society of Clinical Oncology
| Virginia
Julie Gralow, M.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Developing New Methods for Predicting Health Outcomes Using Electronic Health Record Data

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research, Research Conducted Using PCORnet®

Developing New Methods to Study Secure Electronic Messages between Doctors and Patients -- The ECLIPPSE-CER Study

The Regents of the University of California, San Francisco
| California
Dean Schillinger, M.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Comparing Two Ways to Help Patients with Kidney Disease Make Treatment Decisions -- The ExPAND Study

The George Washington University
| District of Columbia
Dale Lupu, MPH, PhD
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Hospital Elder Life Program (HELP) vs. Family-Augmented HELP (FAM-HELP) for Prevention of Delirium

Hebrew Rehabilitation Center
| Massachusetts
Sharon Inouye, MD, MPH
Project Status:
In progress; Recruiting
Funding Type:
Research

Develop Novel Methods to Identify and Characterize Family Relationships from Electronic Health Data

University of Colorado Denver
| Colorado
Toan Ong, PhD, and Lisa Schilling, MD, MSPH
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research

Data-Adaptive Readmissions Models for Heterogeneous and Longitudinal Data

Regents of the University of Minnesota
| Minnesota
Jared Huling, PhD
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research

Promoting Shared Decision Making for Decisions about Treatment of Severe Aortic Stenosis

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Transportability of Machine Learning-Enabled Confounding Control Methods Across EHR Databases

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Richard Wyss, PhD, MS
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research

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