Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. See the Portfolio User Guide.

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year PCORI approved the research study or project for funding. View Glossary
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Displaying 1 - 25 of 174 results

Project Title
Project Status
Funding Type

Improving High Blood Pressure in Older Adults Living with Multiple Chronic Diseases - The SMBP Study

The University of Iowa College of Pharmacy
| Iowa
Korey Kennelty, M.S., Ph.D., Phrm.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Hospital-to-Home Care Coordination for Children and Youth With Special Healthcare Needs

Duke University
| North Carolina
David Ming, MD
Project Status:
Awarded; Contract pending
Funding Type:
Research

Comparative Effectiveness of Brief Motivational Interviewing With and Without Adjunctive App-Delivered Mindfulness Training for Reducing Alcohol Use Among Adolescents in Pediatric Primary Care

Johns Hopkins University School of Medicine
| Maryland
Christopher Hammond, M.D., Ph.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Home-Based Pulmonary Rehabilitation With Health Coaching in Patients With Fibrotic Lung Disease

Mayo Clinic Rochester
| Minnesota
Teng Moua, M.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Improving Outcomes for Patients with Multiple Chronic Conditions Using ECHO

University of New Mexico Health Sciences Center
| New Mexico
Sanjeev Arora, M.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Comorbidity of Chronic Pain and Early Cognitive Decline Among Older, Community-Based Black Adults: Comparative Effectiveness of Mindfulness-Based Cognitive Therapy with walking (MBCT) versus Active Living Every Day (ALED)

Massachusetts General Hospital
| Massachusetts
Olivia Okereke, A.B., M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Models of Post-Acute Care in Complex Older Adults with Fracture

Duke University School of Medicine
| North Carolina
Cathleen Colon-Emeric, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Optimizing Childhood Obesity and Asthma Outcomes in Primary Care via Telehealth

Massachusetts General Hospital
| Massachusetts
Lauren Fiechtner, M.D., MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Enhanced Primary Telecare versus Consultative Complex Care for Children with Medical Complexity

Wake Forest School of Medicine
| North Carolina
Savithri Nageswaran, M.D., MPH, MBBS
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Annual Wellness Visits versus GRACE-augmented Annual Wellness Visits for Older Adults with High Needs

Massachusetts General Hospital
| Massachusetts
Christine Ritchie, M.D., MSPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Generalist versus Specialist Palliative Care for Inpatients

University of Pennsylvania
| Pennsylvania
Scott Halpern, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Functional improvement in Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease with a Telehealth LifeStyle and Exercise Intervention (FOCuSEd)

Seattle Institute for Biomedical and Clinical Research
| Washington
Laura Feemster, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Support for Transgender and Nonbinary Individuals Seeking Vaginoplasty (STRIVE) Study

Oregon Health & Science University
| Oregon
Geolani Dy, M.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

A Comparative Effectiveness Study of Post-Traumatic Stress Disorder Treatments among Sexual and Gender Minority Populations

The Regents of the University of California, San Francisco
| California
Annesa Flentje, Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Developing New Methods for Predicting Health Outcomes Using Electronic Health Record Data

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research, Research Conducted Using PCORnet®

Developing New Methods to Study Secure Electronic Messages between Doctors and Patients -- The ECLIPPSE-CER Study

The Regents of the University of California, San Francisco
| California
Dean Schillinger, M.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Comparing Two Ways to Help Patients with Kidney Disease Make Treatment Decisions -- The ExPAND Study

The George Washington University
| District of Columbia
Dale Lupu, MPH, PhD
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Comparing Two Ways to Help Patients with Autism Manage Emotions and Stress

University of Pittsburgh
| Pennsylvania
Carla Mazefsky, Ph.D.
Project Status:
In progress; Recruiting
Funding Type:
Research

Comparing Cognitive-Behavioral Therapy versus Mindfulness-Based Therapy for Autistic Adults

The University of North Carolina at Chapel Hill
| North Carolina
Brenna Maddox, PhD
Project Status:
In progress; Recruiting
Funding Type:
Research

A Comparison of Two School-Based Interventions to Manage Anxiety in Autistic Students

University of Colorado Denver
| Colorado
Judy Reaven, PhD
Project Status:
In progress; Recruiting
Funding Type:
Research

Reducing Caregiver Burden and Improving Outcomes for Children with Tracheostomies Living at Home

Massachusetts General Hospital
| Massachusetts
Karen Sepucha, PhD
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Can A/B Testing Be Adapted into an Ethical and Useful Approach to Patient-Centered Outcomes Research?

Memorial Sloan Kettering Cancer Center
| New York
James Flory, MD, MS
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research

Comparative Effectiveness of an Individualized Model of Hemodialysis versus Conventional Hemodialysis -- The TwoPlus Trial

Wake Forest University
| North Carolina
Mariana Murea, MD
Project Status:
In progress; Recruiting
Funding Type:
Research

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Funding Type:
Research

Comparing Two Medicines to Treat Coronary Artery Disease in Older Adults -- The LIVE BETTER Trial

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Funding Type:
Research

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