Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. See the Portfolio User Guide.

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year PCORI approved the research study or project for funding. View Glossary
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Displaying 1 - 25 of 462 results

Project Title
Project Status
Funding Type

Comparative Effectiveness of ICD Versus Non-ICD Therapy in Contemporary Heart Failure Patients With a Low Risk for Arrhythmic Death (CONTEMP-ICD)

University of Rochester
| New York
Ilan Goldenberg, M.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Improving the Quality of Care for Asthma Patients at Risk of Exacerbations, i-CARE

Brigham and Women's Hospital
| Massachusetts
Elliot Israel, M.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Improving Safety, Patient Experience, and Equity through Shared Decision-making Huddles

NorthShore University HealthSystem
| Illinois
Ann Borders, M.D., MPH, MSc
Project Status:
Awarded; In progress
Funding Type:
Research

Boston Hypertension Equity Alliance in Treatment: Comparing System-Based Approaches to Hypertension Control in the Safety-Net Setting

Boston Medical Center Corporation
| Massachusetts
Michael Fischer, M.D., MS
Project Status:
Awarded; In progress
Funding Type:
Research

Engage for Equity PLUS: Testing Engagement Strategies to Promote Trustworthy Academic Institutions and Greater Diversity and Capacity for Patient and Community Leadership in Research

University of New Mexico Health Sciences Center
| New Mexico
Nina Wallerstein, Dr.Ph
Project Status:
Awarded; In progress
Funding Type:
Research

RISE Versus Advocacy-Based Enhanced Care as Usual for Patients Experiencing Intimate Partner Violence

Boston VA Research Institute, Inc.
| Massachusetts
Katherine Iverson, M.A., Ph.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Characterizing Engagement and Equity in Research (CHEER)

University of Colorado Denver
| Colorado
Bethany Kwan, Ph.D., MPH
Project Status:
Awarded; In progress
Funding Type:
Research

Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients with Large Vessel OCclusion in the Angiography SuiTe (DIRECT) Trial

University of Iowa
| Iowa
Santiago Ortega-Gutierrez, MD
Project Status:
Awarded; Contract pending
Funding Type:
Research

Hospital-to-Home Care Coordination for Children and Youth With Special Healthcare Needs

Duke University
| North Carolina
David Ming, MD
Project Status:
Awarded; Contract pending
Funding Type:
Research

A Randomized Controlled Trial to Evaluate a Trauma-Informed Partner Violence Intervention Program

Trustees of Boston University, BUMC
| Massachusetts
Casey Taft, Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Improving In-Hospital Sleep Hygiene to Prevent and Curtail Delirium Among Older Adults

The Methodist Hospital Research Institute
| Texas
Farhaan Vahidy, Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

The SCOPE Trial: Sleep, Cognition, and Pain Bundle Versus Enhanced Recovery After Surgery-Cardiac for Postoperative Delirium

Beth Israel Deaconess Medical Center
| Massachusetts
Balachundhar Subramaniam, M.D., MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Causal Mediation Methods for Cluster-Randomized Pragmatic and Implementation Trials

Yale University
| Connecticut
Fan Li, Ph.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Delivering HOPE (Helping Women Optimize Prenatal Equity)

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, M.A., MBA, Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Patient-Level Artificial Intelligence to Derive Longitudinal Phenotypes for Comparative Clinical Effectiveness Research

Dana-Farber Cancer Institute
| Massachusetts
Kenneth Kehl, M.D., MPH
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research

Pathways to Perinatal Mental Health Equity (Pathways)

UMass Chan Medical School
| Massachusetts
Nancy Byatt, B.A., D.O., MBA, M.S.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Preoperative Fasting Versus Not Fasting in Critically Ill Patients

Massachusetts General Hospital/Harvard Medical School
| Massachusetts
Alexander Nagrebetsky, M.D., M.S.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Comparing Analgesic Regimen Effectiveness and Safety for Kids After Surgery

University of Michigan
| Michigan
Mark Bicket, M.D., Ph.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Implementation and Interaction of Clinician and Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure With Reduced Ejection Fraction

University of Colorado Denver
| Colorado
Larry Allen, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

GTI: Comparing Effectiveness of Implementation Strategies to Improve Cancer Screening for Veterans

University of Pittsburgh School of Medicine
| Pennsylvania
Shari Rogal, M.D., MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research, Research Conducted Using PCORnet®

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

Trustees of Indiana University
| Indiana
Zachary Adams, Ph.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

The Dose Trial: Dose Intensity for Behavioral Interventions for Childhood Obesity

Vanderbilt University Medical Center
| Tennessee
William Heerman, M.D., MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Brief Motivational Interviewing With and Without Adjunctive App-Delivered Mindfulness Training for Reducing Alcohol Use Among Adolescents in Pediatric Primary Care

Johns Hopkins University School of Medicine
| Maryland
Christopher Hammond, M.D., Ph.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Remote Hypertension Tracking Help and Management to Reduce Disparities in Black Patients (RHYTHM-B)

Wake Forest University Health Sciences
| North Carolina
Yhenneko Taylor, Ph.D., Mstat
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Home-Based Pulmonary Rehabilitation With Health Coaching in Patients With Fibrotic Lung Disease

Mayo Clinic Rochester
| Minnesota
Teng Moua, M.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

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