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Review
. 2014 Sep;24(9):1499-509.
doi: 10.1007/s11695-014-1276-0.

Incidence of cancer following bariatric surgery: systematic review and meta-analysis

Daniela Schaan Casagrande  1 , Daniela Dornelles Rosa, Daniel Umpierre, Roberta Aguiar Sarmento, Clarissa Garcia Rodrigues, Beatriz D Schaan
Affiliations
Review

Incidence of cancer following bariatric surgery: systematic review and meta-analysis

Daniela Schaan Casagrande et al. Obes Surg. 2014 Sep.

Abstract

Obesity is linked to the development of cancer. Previous studies have suggested that there is a relationship between bariatric surgery and reduced cancer risk. Data sources were from Medline, Embase, and Cochrane Library. From 951 references, 13 studies met the inclusion criteria (54,257 participants). In controlled studies, bariatric surgery was associated with a reduction in the risk of cancer. The cancer incidence density rate was 1.06 cases per 1000 person-years within the surgery groups. In the meta-regression, we found an inverse relationship between the presurgical body mass index and cancer incidence after surgery (beta coefficient -0.2, P < 0.05). Bariatric surgery is associated with reduced cancer risk in morbidly obese people. However, considering the heterogeneity among the studies, conclusions should be drawn with care.

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