Carbohydrate ingestion augments creatine retention during creatine feeding in humans
- PMID: 8899067
- DOI: 10.1046/j.1365-201X.1996.528300000.x
Carbohydrate ingestion augments creatine retention during creatine feeding in humans
Abstract
Blood and urine samples were obtained from four groups of healthy male subjects (A-D, total n = 22) before, during and after ingesting the following: group A, 5 g of creatine in solution; groups B and C, 5 g of creatine and 93 g of simple carbohydrate in solution: group D, a creatine- and carbohydrate-free solution. Subjects ingested the above preparations every 4 h for the remainder of the day and throughout the next day (total daily creatine dose = 20 g), and reported back to the laboratory on day 3 to undergo the same procedures as on day 1. Throughout this time, subjects weighed and recorded all dietary intake, and those in groups B and C ingested a prescribed isoenergetic high carbohydrate diet. Subjects in group C also performed 1 h of cycling exercise at 70% of their maximal oxygen consumption on the morning of each day. On both days 1 and 3, peak plasma creatine concentration, the area under the plasma creatine concentration/time curve and urinary creatine concentration were lower in groups B and C than in group A. Conversely, serum insulin concentration was higher in groups B and C than in A. No differences were evident when comparing groups B and C. These data suggest carbohydrate ingestion augmented creatine retention during creatine feeding and that creatine retention was not further increased when exercise was performed prior to ingestion.
Similar articles
-
Optimization of insulin-mediated creatine retention during creatine feeding in humans.J Sports Sci. 2010 Jan;28(1):67-74. doi: 10.1080/02640410903390071. J Sports Sci. 2010. PMID: 20035494 Clinical Trial.
-
Effects of isoenergetic overfeeding of either carbohydrate or fat in young men.Br J Nutr. 2000 Aug;84(2):233-45. Br J Nutr. 2000. PMID: 11029975
-
Carbohydrate ingestion augments L-carnitine retention in humans.J Appl Physiol (1985). 2007 Mar;102(3):1065-70. doi: 10.1152/japplphysiol.01011.2006. Epub 2006 Nov 30. J Appl Physiol (1985). 2007. PMID: 17138832 Clinical Trial.
-
Altering the temporal distribution of energy intake with isoenergetically dense foods given as snacks does not affect total daily energy intake in normal-weight men.Br J Nutr. 2000 Jan;83(1):7-14. Br J Nutr. 2000. PMID: 10703459 Clinical Trial.
-
Diet composition and the performance of high-intensity exercise.J Sports Sci. 1997 Jun;15(3):265-75. doi: 10.1080/026404197367272. J Sports Sci. 1997. PMID: 9232552 Review.
Cited by
-
The Synergistic Effect of Compound Sugar with Different Glycemic Indices Combined with Creatine on Exercise-Related Fatigue in Mice.Foods. 2024 Feb 3;13(3):489. doi: 10.3390/foods13030489. Foods. 2024. PMID: 38338624 Free PMC article.
-
Creatine O'Clock: Does Timing of Ingestion Really Influence Muscle Mass and Performance?Front Sports Act Living. 2022 May 20;4:893714. doi: 10.3389/fspor.2022.893714. eCollection 2022. Front Sports Act Living. 2022. PMID: 35669557 Free PMC article. Review.
-
Bioavailability, Efficacy, Safety, and Regulatory Status of Creatine and Related Compounds: A Critical Review.Nutrients. 2022 Feb 28;14(5):1035. doi: 10.3390/nu14051035. Nutrients. 2022. PMID: 35268011 Free PMC article. Review.
-
Timing of Creatine Supplementation around Exercise: A Real Concern?Nutrients. 2021 Aug 19;13(8):2844. doi: 10.3390/nu13082844. Nutrients. 2021. PMID: 34445003 Free PMC article. Review.
-
Creatine for Exercise and Sports Performance, with Recovery Considerations for Healthy Populations.Nutrients. 2021 Jun 2;13(6):1915. doi: 10.3390/nu13061915. Nutrients. 2021. PMID: 34199588 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical