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. 1994 Feb;30(2):93-8.
doi: 10.1016/0165-0327(94)90036-1.

Postpartum blues: relationship between not-protein bound steroid hormones in plasma and postpartum mood changes

A Heidrich  1 , M Schleyer, H Spingler, P Albert, M Knoche, J Fritze, M Lanczik
Affiliations

Postpartum blues: relationship between not-protein bound steroid hormones in plasma and postpartum mood changes

A Heidrich et al. J Affect Disord. 1994 Feb.

Abstract

The relationship between non-bound steroid hormone levels in plasma and the occurrence of postpartum mood changes was investigated in 26 newly delivered mothers throughout the first 5 days postpartum. Studies with saliva samples had reported higher concentrations of 17 beta-estradiol and progesterone on the days of symptoms in women experiencing postpartum blues. As there had been a controversy as to how far saliva concentrations reflect free hormone levels in plasma, free hormone levels of 17 beta-estradiol and progesterone were determined in plasma using ultrafiltration. No significant difference concerning free hormone levels could be found between women with and without postpartum blues.

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