A method for selective section of vagal afferent or efferent axons in the rat
- PMID: 7524370
- DOI: 10.1152/ajpregu.1994.267.4.R1136
A method for selective section of vagal afferent or efferent axons in the rat
Abstract
Although normally a mixed nerve, intracranially the vagus separates into dorsal rootlets that contain afferent axons and ventral rootlets that contain efferents. Surgical procedures are described for exposing the ventral surface of the occipital bone at the level where the vagus passes through the posterior lacerated foramen. When the foramen is expanded medially and the dura lanced, the intracranial course of the vagus can be observed by use of an operating microscope. Under these conditions, either the efferent or the afferent rootlets can be severed selectively. When the dorsal rootlets are divided and the contralateral trunk is cut below the diaphragm, a selective bilateral subdiaphragmatic afferent vagotomy is produced with unilateral sparing of the efferents. Cutting the efferents intracranially has the converse effect.
Similar articles
-
Selective vagal rhizotomies: a new dorsal surgical approach used for intestinal deafferentations.Am J Physiol. 1995 Nov;269(5 Pt 2):R1279-88. doi: 10.1152/ajpregu.1995.269.5.R1279. Am J Physiol. 1995. PMID: 7503320
-
Vagal afferent and efferent contributions to the inhibition of food intake by cholecystokinin.Am J Physiol. 1997 Apr;272(4 Pt 2):R1245-51. doi: 10.1152/ajpregu.1997.272.4.R1245. Am J Physiol. 1997. PMID: 9140026
-
Central projections of coarse and fine vagal axons of the cat.Brain Res. 1990 Mar 5;510(2):351-4. doi: 10.1016/0006-8993(90)91390-3. Brain Res. 1990. PMID: 1691954
-
Functional characteristics of neuropeptides in the dorsal medulla oblongata and vagus nerve.Fed Proc. 1987 Jan;46(1):30-5. Fed Proc. 1987. PMID: 3026859 Review.
-
Role of the efferent and afferent vagus nerve in the development of ventromedial hypothalamic (VMH) obesity.Brain Res Bull. 1991 Sep-Oct;27(3-4):511-5. doi: 10.1016/0361-9230(91)90151-9. Brain Res Bull. 1991. PMID: 1959054 Review.
Cited by
-
"To brain or not to brain": evaluating the possible direct effects of the satiety factor oleoylethanolamide in the central nervous system.Front Endocrinol (Lausanne). 2023 May 10;14:1158287. doi: 10.3389/fendo.2023.1158287. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37234803 Free PMC article.
-
Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions.Biol Open. 2022 Dec 15;11(12):bio059634. doi: 10.1242/bio.059634. Epub 2022 Dec 19. Biol Open. 2022. PMID: 36420826 Free PMC article.
-
The controversial role of the vagus nerve in mediating ghrelin's actions: gut feelings and beyond.IBRO Neurosci Rep. 2022 Mar 12;12:228-239. doi: 10.1016/j.ibneur.2022.03.003. eCollection 2022 Jun. IBRO Neurosci Rep. 2022. PMID: 35746965 Free PMC article. Review.
-
Detection of G Protein-coupled Receptor Expression in Mouse Vagal Afferent Neurons using Multiplex In Situ Hybridization.J Vis Exp. 2021 Sep 20;(175):10.3791/62945. doi: 10.3791/62945. J Vis Exp. 2021. PMID: 34605820 Free PMC article.
-
The physiological control of eating: signals, neurons, and networks.Physiol Rev. 2022 Apr 1;102(2):689-813. doi: 10.1152/physrev.00028.2020. Epub 2021 Sep 6. Physiol Rev. 2022. PMID: 34486393 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources