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Review
. 2023 Mar 16;3(4):100197.
doi: 10.1016/j.xjidi.2023.100197. eCollection 2023 Jul.

Nanoparticles as a Therapeutic Delivery System for Skin Cancer Prevention and Treatment

Jungsoo Chang  1   2 , Beverly Yu  1   2 , W Mark Saltzman  2 , Michael Girardi  1
Affiliations
Review

Nanoparticles as a Therapeutic Delivery System for Skin Cancer Prevention and Treatment

Jungsoo Chang et al. JID Innov. .

Abstract

The use of nanoparticles (NPs) as a therapeutic delivery system has expanded markedly over the past decade, particularly regarding applications targeting the skin. The delivery of NP-based therapeutics to the skin requires special consideration owing to its role as both a physical and immunologic barrier, and specific technologies must not only take into consideration the target but also the pathway of delivery. The unique challenge this poses has been met with the development of a wide panel of NP-based technologies meant to precisely address these considerations. In this review article, we describe the application of NP-based technologies for drug delivery targeting the skin, summarize the types of NPs, and discuss the current landscape of NPs for skin cancer prevention and skin cancer treatment as well as future directions within these applications.

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Figures

Figure 1
Figure 1
Topical and intracutaneous delivery of nanoparticles.
Figure 2
Figure 2
Types of nanoparticles and their advantages and disadvantages.
See this image and copyright information in PMC

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