Repetitive transcranial magnetic stimulation for major depression: A naturalistic observational study in an Australian private hospital
- PMID: 32763538
- DOI: 10.1016/j.psychres.2020.113275
Repetitive transcranial magnetic stimulation for major depression: A naturalistic observational study in an Australian private hospital
Abstract
Repetitive transcranial magnetic stimulation (rTMS) is an effective and evidence-based treatment for major depression, which is now as a mainstream treatment in clinical practice. However, there is limited data concerning its use in Australian private psychiatric hospital settings. This retrospective study examined routinely collected data of 153 inpatients, who received 20 rTMS treatments over four weeks. Primary outcomes measures were the 17-item Hamilton Depression Rating Scale (HAMD-17) and the 21-item Depression, Anxiety and Stress Scale (DASS-21). At post-treatment, response and remission rates were 54% and 28%, respectively, for the HAMD-17; and 53% response and 16% remission rates, for the DASS-21 Depression subscale, respectively. Although no gender differences were observed, younger patients demonstrated more improvements during acute rTMS but the effect was not significant after accounting for pre-treatment symptom severity. The findings of this naturalistic study suggest that an acute course of rTMS provided in private clinical settings resulted in similar response and remission rates to longer rTMS courses. Shorter rTMS courses appear to have satisfactory efficacy in treating major depression, in clinically diverse and real-world practice.
Keywords: Major depression; Naturalistic; Remission; Response; rTMS.
Copyright © 2020 Elsevier B.V. All rights reserved.
Conflict of interest statement
Declaration of Competing Interest The authors declare that they have no conflict of interest.
Similar articles
-
Add-on rTMS for the acute treatment of depressive symptoms is probably more effective in adolescents than in adults: Evidence from real-world clinical practice.Brain Stimul. 2019 Jan-Feb;12(1):103-109. doi: 10.1016/j.brs.2018.09.007. Epub 2018 Sep 14. Brain Stimul. 2019. PMID: 30237010 Clinical Trial.
-
Equal remission rates and reduced length of hospital stay with twice-daily repetitive transcranial magnetic stimulation (rTMS) for major depression - A large naturalistic retrospective cohort association study.Prog Neuropsychopharmacol Biol Psychiatry. 2023 Dec 20;127:110820. doi: 10.1016/j.pnpbp.2023.110820. Epub 2023 Jul 3. Prog Neuropsychopharmacol Biol Psychiatry. 2023. PMID: 37406796
-
A Comparison of Right Unilateral and Sequential Bilateral Repetitive Transcranial Magnetic Stimulation for Major Depression: A Naturalistic Clinical Australian Study.J ECT. 2017 Mar;33(1):58-62. doi: 10.1097/YCT.0000000000000359. J ECT. 2017. PMID: 27753761
-
Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Ont Health Technol Assess Ser. 2016 Mar 1;16(5):1-66. eCollection 2016. Ont Health Technol Assess Ser. 2016. PMID: 27099642 Free PMC article. Review.
-
[Efficacy of repetitive transcranial magnetic stimulation (rTMS) in major depression: a review].Encephale. 2007 Mar-Apr;33(2):126-34. doi: 10.1016/s0013-7006(07)91542-0. Encephale. 2007. PMID: 17675907 Review. French.
Cited by
-
Add-On Intermittent Theta Burst Stimulation Improves the Efficacy of First-Episode and Recurrent Major Depressive Disorder: Real-World Clinical Practice.Neuropsychiatr Dis Treat. 2023 Jan 13;19:109-116. doi: 10.2147/NDT.S388774. eCollection 2023. Neuropsychiatr Dis Treat. 2023. PMID: 36660319 Free PMC article.
-
Long-Term Management of Generalised Anxiety Disorder with Low-Dose Continuous Infusions of Flumazenil: A Case Series.Behav Sci (Basel). 2022 Nov 2;12(11):430. doi: 10.3390/bs12110430. Behav Sci (Basel). 2022. PMID: 36354407 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
