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Review
. 2019 Jul;132(7):802-807.
doi: 10.1016/j.amjmed.2019.03.001. Epub 2019 Mar 16.

Parkinson's Disease and Parkinsonism

Michael T Hayes  1
Affiliations
Review

Parkinson's Disease and Parkinsonism

Michael T Hayes. Am J Med. 2019 Jul.

Abstract

Parkinson's disease is a progressive neurodegenerative disease characterized by tremor and bradykinesia and is a common neurologic ailment. Male sex and advancing age are independent risk factors and, as the population ages, is taking an increasing toll on productivity and medical resources. There are a number of other extrapyramidal conditions that can make the diagnosis challenging. Unlike other neurodegenerative diseases, idiopathic Parkinson's disease has effective treatments that mitigate symptoms. Medications can improve day-to-day function and, in cases where medication does not give a sustained benefit or has significant side effects, treatments like deep brain stimulation result in improved quality of life.

Keywords: Deep brain stimulation; Parkinson's disease; Parkinsonism; Pharmacologic treatment.

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