Review

. 2019 Feb 7;21(2):10.

doi: 10.1007/s11920-019-0997-0.

Global Burden of Disease and the Impact of Mental and Addictive Disorders

Jürgen Rehm^{1

2

3

4

5

6

7}, Kevin D Shield^{8

9

10}

Affiliations

¹ Institute for Clinical Psychology and Psychotherapy, TU Dresden, Chemnitzer Str. 46, 01187, Dresden, Germany. jtrehm@gmail.com.
² Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada. jtrehm@gmail.com.
³ WHO Collaboration Centre, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada. jtrehm@gmail.com.
⁴ Institute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada. jtrehm@gmail.com.
⁵ Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada. jtrehm@gmail.com.
⁶ Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, M5T 3M7, Canada. jtrehm@gmail.com.
⁷ Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, M5T 1R8, Canada. jtrehm@gmail.com.
⁸ Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada.
⁹ WHO Collaboration Centre, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada.
¹⁰ Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, M5T 3M7, Canada.

PMID: 30729322
DOI: 10.1007/s11920-019-0997-0

Review

Global Burden of Disease and the Impact of Mental and Addictive Disorders

Jürgen Rehm et al. Curr Psychiatry Rep. 2019.

. 2019 Feb 7;21(2):10.

doi: 10.1007/s11920-019-0997-0.

Authors

Jürgen Rehm^{1

2

3

4

5

6

7}, Kevin D Shield^{8

9

10}

Affiliations

¹ Institute for Clinical Psychology and Psychotherapy, TU Dresden, Chemnitzer Str. 46, 01187, Dresden, Germany. jtrehm@gmail.com.
² Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada. jtrehm@gmail.com.
³ WHO Collaboration Centre, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada. jtrehm@gmail.com.
⁴ Institute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada. jtrehm@gmail.com.
⁵ Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada. jtrehm@gmail.com.
⁶ Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, M5T 3M7, Canada. jtrehm@gmail.com.
⁷ Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, M5T 1R8, Canada. jtrehm@gmail.com.
⁸ Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada.
⁹ WHO Collaboration Centre, Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada.
¹⁰ Dalla Lana School of Public Health, University of Toronto, 155 College Street, Toronto, Ontario, M5T 3M7, Canada.

PMID: 30729322
DOI: 10.1007/s11920-019-0997-0

Abstract

Purpose of review: This contribution reviews the newest empirical evidence regarding the burden of mental and addictive disorders and weighs their importance for global health in the first decades of the twenty-first century.

Recent findings: Mental and addictive disorders affected more than 1 billion people globally in 2016. They caused 7% of all global burden of disease as measured in DALYs and 19% of all years lived with disability. Depression was associated with most DALYs for both sexes, with higher rates in women as all other internalizing disorders, whereas other disorders such as substance use disorders had higher rates in men. Mental and addictive disorders affect a significant portion of the global population with high burden, in particular in high- and upper-middle-income countries. The relative share of these disorders has increased in the past decades, in part due to stigma and lack of treatment. Future research needs to better analyze the role of mental and addictive disorders in shifts of life expectancy.

Keywords: Deaths of despair; Excess mortality; Global burden of disease; Life expectancy; Mental disorders; Substance-use disorders.

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References

1. Brookings Pap Econ Act. 2017 Spring;2017:397-476 - PubMed
1. Soc Sci Med. 2010 Aug;71(3):517-528 - PubMed
1. Addiction. 2019 May;114(5):771-773 - PubMed
1. Epidemiol Psychiatr Sci. 2018 Oct;27(5):463-467 - PubMed
1. Milbank Mem Fund Q. 1971 Oct;49(4):509-38 - PubMed

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Global Burden of Disease and the Impact of Mental and Addictive Disorders

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