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. 2018 Apr;69(4):339-346.
doi: 10.1177/0003319717721603. Epub 2017 Jul 21.

Western Dietary Pattern Is Associated With Severe Coronary Artery Disease

Evangelos Oikonomou  1 , Theodora Psaltopoulou  2 , Georgios Georgiopoulos  1 , Gerasimos Siasos  1   3 , Eleni Kokkou  1 , Alexios Antonopoulos  1 , Georgia Vogiatzi  1 , Sotirios Tsalamandris  1 , Vassiliki Gennimata  1 , Aggelos Papanikolaou  1 , Dimitris Tousoulis  1
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Western Dietary Pattern Is Associated With Severe Coronary Artery Disease

Evangelos Oikonomou et al. Angiology. 2018 Apr.

Abstract

The independent predictive value of an unhealthy diet on the severity of coronary artery disease (CAD) requires further investigation. We assessed the impact of dietary pattern on CAD severity. In this cohort study, we included 188 symptomatic stable patients with CAD. Patients were categorized as having severe CAD or nonsevere CAD by coronary angiography. Among several demographics and clinical characteristics, all patients were tested using a semiquantitative food frequency questionnaire. Concerning baseline demographic characteristics, there was no difference between patients with severe CAD and nonsevere CAD. Principal component analysis revealed 8 distinct dietary patterns. The first component Western dietary pattern (increased intake of fat, red meat, and carbohydrates and minimal consumption of fruits and green leafy vegetables) was predictive of severe CAD (area under the curve: 0.73, 95% confidence intervals: 0.64-0.83, P < .001). In conclusion, an unhealthy Western type of diet is associated with the severity of coronary artery lesions in patients with stable CAD. These findings highlight the role of dietary patterns when estimating cardiovascular risk for the management of patients with CAD.

Keywords: Western type of diet; atherosclerosis; carbohydrates; coronary artery disease; fat.

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