Cognitive and motor reaction times in obstructive sleep apnea syndrome: A study based on computerized measures

Affiliations

¹ Department of Human and Social Sciences, University of Bergamo, Italy. Electronic address: maria.devita@unibg.it.
² Department of General Psychology, University of Padua, Italy; Human Inspired Technology Research Centre, University of Padua, Italy. Electronic address: sn.montemurro@gmail.com.
³ Department of General Psychology, University of Padua, Italy; Human Inspired Technology Research Centre, University of Padua, Italy. Electronic address: andrea.zangrossi@gmail.com.
⁴ Internal Medicine Unit, Figlie di S. Camillo, Cremona, Italy. Electronic address: sararamponi79@gmail.com.
⁵ Internal Medicine Unit, Figlie di S. Camillo, Cremona, Italy; Department of Internal Medicine and Pneumology, University of Parma, Italy. Electronic address: medicina.cr@figliesancamillo.it.
⁶ Neuromotor Rehabilitation Unit, Figlie di S. Camillo, Cremona, Italy. Electronic address: daniele.villani50@gmail.com.
⁷ Neuromotor Rehabilitation Unit, Figlie di S. Camillo, Cremona, Italy. Electronic address: clara2.13@icloud.com.
⁸ Neurological Unit, U.V.A. Centre, Humanitas Gavazzeni, Bergamo, Italy. Electronic address: paola.merlo@gavazzeni.it.
⁹ Department of Human and Social Sciences, University of Bergamo, Italy. Electronic address: marialuisa.rusconi@unibg.it.
¹⁰ Department of General Psychology, University of Padua, Italy; Human Inspired Technology Research Centre, University of Padua, Italy. Electronic address: sara.mondini@unipd.it.

PMID: 28700954
DOI: 10.1016/j.bandc.2017.07.002

Cognitive and motor reaction times in obstructive sleep apnea syndrome: A study based on computerized measures

Maria Devita et al. Brain Cogn. 2017 Oct.

. 2017 Oct:117:26-32.

doi: 10.1016/j.bandc.2017.07.002. Epub 2017 Jul 9.

Authors

Affiliations

¹ Department of Human and Social Sciences, University of Bergamo, Italy. Electronic address: maria.devita@unibg.it.
² Department of General Psychology, University of Padua, Italy; Human Inspired Technology Research Centre, University of Padua, Italy. Electronic address: sn.montemurro@gmail.com.
³ Department of General Psychology, University of Padua, Italy; Human Inspired Technology Research Centre, University of Padua, Italy. Electronic address: andrea.zangrossi@gmail.com.
⁴ Internal Medicine Unit, Figlie di S. Camillo, Cremona, Italy. Electronic address: sararamponi79@gmail.com.
⁵ Internal Medicine Unit, Figlie di S. Camillo, Cremona, Italy; Department of Internal Medicine and Pneumology, University of Parma, Italy. Electronic address: medicina.cr@figliesancamillo.it.
⁶ Neuromotor Rehabilitation Unit, Figlie di S. Camillo, Cremona, Italy. Electronic address: daniele.villani50@gmail.com.
⁷ Neuromotor Rehabilitation Unit, Figlie di S. Camillo, Cremona, Italy. Electronic address: clara2.13@icloud.com.
⁸ Neurological Unit, U.V.A. Centre, Humanitas Gavazzeni, Bergamo, Italy. Electronic address: paola.merlo@gavazzeni.it.
⁹ Department of Human and Social Sciences, University of Bergamo, Italy. Electronic address: marialuisa.rusconi@unibg.it.
¹⁰ Department of General Psychology, University of Padua, Italy; Human Inspired Technology Research Centre, University of Padua, Italy. Electronic address: sara.mondini@unipd.it.

PMID: 28700954
DOI: 10.1016/j.bandc.2017.07.002

Abstract

Obstructive Sleep Apnea Syndrome (OSAS) is mainly associated with executive dysfunction. Although delayed reaction times (RTs) in patients with OSAS have been reported, sensitivity of processing speed has not been adequately assessed. This study suggests sensitive and reliable measures to clarify whether different components of information processing speed, i.e. cognitive and motor responses, are equally impaired in OSAS. Thirty-three patients with OSAS were compared with thirty healthy controls. The MoCA test was administered to assess participants' global neuropsychological profile. Cognitive and motor reaction times were measured using a detector panel which allows to distinguish between stimulus encoding, decision processing, and selection of the appropriate motor response. Logistic regression models highlighted both MoCA test and motor RTs as the best predictors differentiating patients from healthy participants. Results support the hypothesis of a slight decline in the cognitive profile of patients with OSAS and identify significant slowing down in the motor component of responses. It could be hypothesized that slower motor responsiveness is the cause of the global cognitive profile of these patients. With aging, motor movements and RTs usually become impaired and hypoxia might accelerate the aging process by compromising first of all the motor component of RTs.

Keywords: Cognitive decline; Cognitive reaction times; Hypoxia; Motor reaction times; Obstructive sleep apnea.

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Cognitive and motor reaction times in obstructive sleep apnea syndrome: A study based on computerized measures

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Cognitive and motor reaction times in obstructive sleep apnea syndrome: A study based on computerized measures

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