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Review
. 2016 Mar 18;6(3):e010137.
doi: 10.1136/bmjopen-2015-010137.

Association between subjective social status and cardiovascular disease and cardiovascular risk factors: a systematic review and meta-analysis

Affiliations
Review

Association between subjective social status and cardiovascular disease and cardiovascular risk factors: a systematic review and meta-analysis

Karen L Tang et al. BMJ Open. .

Abstract

Objective: To determine the association between subjective social status (SSS), or the individual's perception of his or her position in the social hierarchy, and the odds of coronary artery disease (CAD), hypertension, diabetes, obesity and dyslipidaemia.

Study design: Systematic review and meta-analysis.

Methods: We searched PubMed, MEDLINE, EMBASE, CINAHL, PsycINFO, SocINDEX, Web of Science and reference lists of all included studies up to October 2014, with a verification search in July 2015. Inclusion criteria were original studies in adults that reported odds, risk or hazard ratios of at least one outcome of interest (CAD, hypertension, diabetes, obesity or dyslipidaemia), comparing 'lower' versus 'higher' SSS groups, where SSS is measured on a self-anchoring ladder. ORs were pooled using a random-effects model.

Results: 10 studies were included in the systematic review; 9 of these were included in the meta-analysis. In analyses unadjusted for objective socioeconomic status (SES) measures such as income, education or occupation, the pooled OR comparing the bottom versus the top of the SSS ladder was 1.82 (95% CI 1.10 to 2.99) for CAD, 1.88 (95% CI 1.27 to 2.79) for hypertension, 1.90 (95% CI 1.25 to 2.87) for diabetes, 3.68 (95% CI 2.03 to 6.64) for dyslipidaemia and 1.57 (95% CI 0.95 to 2.59) for obesity. These associations were attenuated when adjusting for objective SES measures, with the only statistically significant association remaining for dyslipidaemia (OR 2.10, 95% CI 1.09 to 4.06), though all ORs remained greater than 1.

Conclusions: Lower SSS is associated with significantly increased odds of CAD, hypertension, diabetes and dyslipidaemia, with a trend towards increased odds of obesity. These trends are consistently present, though the effects attenuated when adjusting for SES, suggesting that perception of one's own status on a social hierarchy has health effects above and beyond one's actual income, occupation and education.

Keywords: CARDIOLOGY; EPIDEMIOLOGY; INTERNAL MEDICINE; PUBLIC HEALTH; SOCIAL MEDICINE.

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Figures

Figure 1
Figure 1
Flow diagram of the study selection process.
Figure 2
Figure 2
Forest plot of ORs of coronary artery disease, hypertension, diabetes, dyslipidaemia and obesity comparing the bottom with the top of the subjective social status ladder, unadjusted for socioeconomic status.
Figure 3
Figure 3
Forest plot of ORs of coronary artery disease, hypertension, diabetes, dyslipidaemia and obesity comparing the bottom with the top of the subjective social status ladder, adjusted for socioeconomic status.
Figure 4
Figure 4
Forest plots of OR of hypertension (A), diabetes (B) and obesity (C) comparing the bottom with the top of the subjective social status ladder, stratified by ethnicity.

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