Comprehensive real-time epidemiological data from respiratory infections in Finland between 2010 and 2014 obtained from an automated and multianalyte mariPOC® respiratory pathogen test
- PMID: 26740322
- PMCID: PMC7088327
- DOI: 10.1007/s10096-015-2553-0
Comprehensive real-time epidemiological data from respiratory infections in Finland between 2010 and 2014 obtained from an automated and multianalyte mariPOC® respiratory pathogen test
Abstract
Respiratory viruses cause seasonal epidemics every year. Several respiratory pathogens are circulating simultaneously and typical symptoms of different respiratory infections are alike, meaning it is challenging to identify and diagnose different respiratory pathogens based on symptoms alone. mariPOC® is an automated, multianalyte antigen test which allows the rapid detection of nine respiratory infection pathogens [influenza A and B viruses, respiratory syncytial virus (RSV), human metapneumovirus, adenovirus, parainfluenza 1-3 viruses and pneumococci] from a single nasopharyngeal swab or aspirate samples, and, in addition, can be linked to laboratory information systems. During the study period from November 2010 to June 2014, a total of 22,485 multianalyte respi tests were performed in the 14 participating laboratories in Finland and, in total, 6897 positive analyte results were recorded. Of the tested samples, 25 % were positive for one respiratory pathogen, with RSV (9.8 %) and influenza A virus (7.2 %) being the most common findings, and 0.65 % of the samples were multivirus-positive. Only small geographical variations in seasonal epidemics occurred. Our results show that the mariPOC® multianalyte respi test allows simultaneous detection of several respiratory pathogens in real time. The results are reliable and give the clinician a picture of the current epidemiological situation, thus minimising guesswork.
Conflict of interest statement
None.
Figures
![Fig. 1](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/7088327/bin/10096_2015_2553_Fig1_HTML.gif)
![Fig. 2](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/7088327/bin/10096_2015_2553_Fig2_HTML.gif)
![Fig. 3](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/7088327/bin/10096_2015_2553_Fig3_HTML.gif)
![Fig. 4](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/7088327/bin/10096_2015_2553_Fig4_HTML.gif)
![Fig. 5](https://cdn.statically.io/img/www.ncbi.nlm.nih.gov/pmc/articles/instance/7088327/bin/10096_2015_2553_Fig5_HTML.gif)
Similar articles
-
Identification of respiratory viruses with a novel point-of-care multianalyte antigen detection test in children with acute respiratory tract infection.J Clin Virol. 2013 Jun;57(2):136-40. doi: 10.1016/j.jcv.2013.02.011. Epub 2013 Mar 11. J Clin Virol. 2013. PMID: 23490399 Free PMC article.
-
Analytical performance of the automated multianalyte point-of-care mariPOC® for the detection of respiratory viruses.Diagn Microbiol Infect Dis. 2015 Nov;83(3):252-6. doi: 10.1016/j.diagmicrobio.2015.07.010. Epub 2015 Jul 18. Diagn Microbiol Infect Dis. 2015. PMID: 26283523 Free PMC article.
-
Evaluation of the automated multianalyte point-of-care mariPOC® test for the detection of influenza A virus and respiratory syncytial virus.J Med Virol. 2013 Sep;85(9):1598-601. doi: 10.1002/jmv.23660. J Med Virol. 2013. PMID: 23852685
-
Respiratory viral infections in transplant recipients.Antivir Ther. 2007;12(4 Pt B):627-38. Antivir Ther. 2007. PMID: 17944270 Review.
-
Point-of-care diagnostics for respiratory viral infections.Expert Rev Mol Diagn. 2018 Jan;18(1):75-83. doi: 10.1080/14737159.2018.1419065. Epub 2017 Dec 26. Expert Rev Mol Diagn. 2018. PMID: 29251007 Free PMC article. Review.
Cited by
-
Viral Etiology and Clinical Characteristics of Acute Respiratory Tract Infections in Hospitalized Children in Southern Germany (2014-2018).Open Forum Infect Dis. 2023 Mar 1;10(3):ofad110. doi: 10.1093/ofid/ofad110. eCollection 2023 Mar. Open Forum Infect Dis. 2023. PMID: 36968956 Free PMC article.
-
Clinical validation of automated and rapid mariPOC SARS-CoV-2 antigen test.Sci Rep. 2021 Oct 13;11(1):20363. doi: 10.1038/s41598-021-99886-6. Sci Rep. 2021. PMID: 34645929 Free PMC article.
-
Respiratory Syncytial Virus (RSV)-Specific Antibodies in Pregnant Women and Subsequent Risk of RSV Hospitalization in Young Infants.J Infect Dis. 2022 Apr 1;225(7):1189-1196. doi: 10.1093/infdis/jiab315. J Infect Dis. 2022. PMID: 34129040 Free PMC article.
-
Epidemiology and genetic characterization of respiratory syncytial virus in children with acute respiratory infections: Findings from the influenza sentinel surveillance network in Central African Republic, 2015 to 2018.Health Sci Rep. 2021 May 11;4(2):e298. doi: 10.1002/hsr2.298. eCollection 2021 Jun. Health Sci Rep. 2021. PMID: 34013070 Free PMC article.
-
Rapid detection and monitoring of human coronavirus infections.New Microbes New Infect. 2018 May 9;24:52-55. doi: 10.1016/j.nmni.2018.04.007. eCollection 2018 Jul. New Microbes New Infect. 2018. PMID: 29872531 Free PMC article.
References
-
- National Institute for Health and Welfare (2015) Infectious diseases in Finland. Home page at: https://www.thl.fi/en/web/infectious-diseases/about
-
- European Centre for Disease Prevention and Control (ECDC) (2015) Seasonal influenza epidemiology. Available online at: http://ecdc.europa.eu/en/healthtopics/seasonal_influenza/epidemiological...
-
- World Health Organization (WHO) (2015) FluID—a global influenza epidemiological data sharing platform. Home page at: http://www.who.int/influenza/surveillance_monitoring/fluid/en/
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources