The role of socio-economic status and perinatal factors in racial disparities in the risk of cerebral palsy
- PMID: 25808915
- PMCID: PMC4529795
- DOI: 10.1111/dmcn.12746
The role of socio-economic status and perinatal factors in racial disparities in the risk of cerebral palsy
Abstract
Aim: To determine whether racial disparities in cerebral palsy (CP) risk among US children persist after controlling for socio-economic status (SES) (here indicated by maternal education) and perinatal risk factors.
Method: A population-based birth cohort study was conducted using the Autism and Developmental Disabilities Monitoring Network surveillance and birth data for 8-year-old children residing in multi-county areas in Alabama, Georgia, Missouri, and Wisconsin between 2002 and 2008. The birth cohort comparison group included 458 027 children and the case group included 1570 children with CP, 1202 with available birth records. χ(2) tests were performed to evaluate associations and logistic regression was used to calculate relative risks (RR) and adjusted odds ratios (OR) with 95% confidence intervals (CI).
Results: The risk of spastic CP was more than 50% higher for black versus white children (RR 1.52, 95% CI 1.33-1.73), and this greater risk persisted after adjustment for SES (OR 1.35, 95% CI 1.18-1.55), but not after further adjustment for preterm birth and size for gestational age. The protective effect of maternal education remained after adjustment for race/ethnicity and perinatal factors.
Interpretation: Maternal education appears to independently affect CP risk but does not fully explain existing racial disparities in CP prevalence in the US.
© 2015 Mac Keith Press.
Conflict of interest statement
The authors have stated that they had no interests which might be perceived as posing a conflict or bias.
Comment in
-
Disentangling racial and ethnic disparities in cerebral palsy.Dev Med Child Neurol. 2015 Sep;57(9):791-2. doi: 10.1111/dmcn.12772. Epub 2015 Apr 21. Dev Med Child Neurol. 2015. PMID: 25900384 No abstract available.
Similar articles
-
Season of Conception and Risk of Cerebral Palsy.JAMA Netw Open. 2023 Sep 5;6(9):e2335164. doi: 10.1001/jamanetworkopen.2023.35164. JAMA Netw Open. 2023. PMID: 37738049 Free PMC article.
-
Cerebral palsy and perinatal mortality after pregnancy-induced hypertension across the gestational age spectrum: observations of a reconstructed total population cohort.Dev Med Child Neurol. 2016 Feb;58 Suppl 2:76-81. doi: 10.1111/dmcn.13014. Epub 2016 Jan 14. Dev Med Child Neurol. 2016. PMID: 26762763
-
Contribution of socio-economic status on the prevalence of cerebral palsy: a systematic search and review.Dev Med Child Neurol. 2014 Nov;56(11):1043-51. doi: 10.1111/dmcn.12456. Epub 2014 Apr 19. Dev Med Child Neurol. 2014. PMID: 24750064 Review.
-
Perinatal complications and socio-economic differences in cerebral palsy in Sweden - a national cohort study.BMC Pediatr. 2008 Oct 30;8:49. doi: 10.1186/1471-2431-8-49. BMC Pediatr. 2008. PMID: 18973666 Free PMC article.
-
Prevalence of cerebral palsy in 8-year-old children in three areas of the United States in 2002: a multisite collaboration.Pediatrics. 2008 Mar;121(3):547-54. doi: 10.1542/peds.2007-1270. Pediatrics. 2008. PMID: 18310204
Cited by
-
Determinants of cerebral palsy in children: systematic review.Sudan J Paediatr. 2023;23(2):126-144. doi: 10.24911/SJP.106-1670589241. Sudan J Paediatr. 2023. PMID: 38380410 Free PMC article. Review.
-
Season of Conception and Risk of Cerebral Palsy.JAMA Netw Open. 2023 Sep 5;6(9):e2335164. doi: 10.1001/jamanetworkopen.2023.35164. JAMA Netw Open. 2023. PMID: 37738049 Free PMC article.
-
Improving Retention of Diverse Samples in Longitudinal Research on Developmental Disabilities.Am J Intellect Dev Disabil. 2023 Mar 1;128(2):164-175. doi: 10.1352/1944-7558-128.2.164. Am J Intellect Dev Disabil. 2023. PMID: 36807478 Free PMC article.
-
Effect of an augmented reality active video game for gait training in children with cerebral palsy following single-event multilevel surgery: protocol for a randomised controlled trial.BMJ Open. 2022 Oct 10;12(10):e061580. doi: 10.1136/bmjopen-2022-061580. BMJ Open. 2022. PMID: 36216413 Free PMC article.
-
Prevalence and characteristics of children with cerebral palsy according to socioeconomic status of areas of residence in a French department.PLoS One. 2022 May 19;17(5):e0268108. doi: 10.1371/journal.pone.0268108. eCollection 2022. PLoS One. 2022. PMID: 35588131 Free PMC article.
References
-
- Dolk H, Pattenden S, Bonellie S, et al. Socio-economic inequalities in cerebral palsy prevalence in the United Kingdom: a register-based study. Paediatr Perinat Epidemiol. 2010;24:149–155. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous