A selective involvement of putamen functional connectivity in youth with internet gaming disorder

Affiliations

¹ Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria, Australia; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia; Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
² Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria, Australia.
³ Department of Child Development and Family Studies, College of Human Ecology, Seoul National University, Seoul, Republic of Korea.
⁴ Seoul-Top Psychiatric Clinic, Gyeonggi, Republic of Korea.
⁵ Interdisciplinary Program (Early Childhood Education Major), College of Education, Seoul National University, Seoul, Republic of Korea.
⁶ Department of Education (Educational Counseling Major), College of Education, Seoul National University, Seoul, Republic of Korea.
⁷ Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
⁸ Department of Child Development and Family Studies, College of Human Ecology, Seoul National University, Seoul, Republic of Korea. Electronic address: ysh@snu.ac.kr.

PMID: 25553620
DOI: 10.1016/j.brainres.2014.12.042

A selective involvement of putamen functional connectivity in youth with internet gaming disorder

Soon-Beom Hong et al. Brain Res. 2015.

. 2015 Mar 30:1602:85-95.

doi: 10.1016/j.brainres.2014.12.042. Epub 2014 Dec 29.

Authors

Affiliations

¹ Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria, Australia; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia; Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
² Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Victoria, Australia.
³ Department of Child Development and Family Studies, College of Human Ecology, Seoul National University, Seoul, Republic of Korea.
⁴ Seoul-Top Psychiatric Clinic, Gyeonggi, Republic of Korea.
⁵ Interdisciplinary Program (Early Childhood Education Major), College of Education, Seoul National University, Seoul, Republic of Korea.
⁶ Department of Education (Educational Counseling Major), College of Education, Seoul National University, Seoul, Republic of Korea.
⁷ Division of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
⁸ Department of Child Development and Family Studies, College of Human Ecology, Seoul National University, Seoul, Republic of Korea. Electronic address: ysh@snu.ac.kr.

PMID: 25553620
DOI: 10.1016/j.brainres.2014.12.042

Abstract

Brain cortico-striatal circuits have consistently been implicated in the pathology of addiction related disorders. We applied a reliable seed-based analysis of the resting-state brain activity to comprehensively delineate the subdivisions of striatal functional connectivity implicated in internet gaming disorder. Among twelve right-handed male adolescents with internet gaming disorder and 11 right-handed and gender-matched healthy controls, we examined group differences in the functional connectivity of dorsal and ventral subdivisions of the caudate nucleus and putamen, as well as the association of these connectivity indices with behavioral measures of internet use. Adolescents with internet gaming disorder showed significantly reduced dorsal putamen functional connectivity with the posterior insula-parietal operculum. More time spent playing online games predicted significantly greater functional connectivity between the dorsal putamen and bilateral primary somatosensory cortices in adolescents with internet gaming disorder, and significantly lower functional connectivity between the dorsal putamen and bilateral sensorimotor cortices in healthy controls. The dorsal putamen functional connectivity was significantly and specifically different in adolescents with internet gaming disorder. The findings suggest a possible biomarker of internet gaming disorder.

Keywords: Cortico-striatal circuits; Functional connectivity; Internet gaming disorder; Magnetic resonance imaging; Network; Putamen.

PubMed Disclaimer

Cited by

Neural correlates of model-based behavior in internet gaming disorder and alcohol use disorder.
Kwon M, Choi H, Park H, Ahn WY, Jung YC. Kwon M, et al. J Behav Addict. 2024 Mar 8;13(1):236-249. doi: 10.1556/2006.2024.00006. Print 2024 Mar 26. J Behav Addict. 2024. PMID: 38460004 Free PMC article.
The Effects of Digital Addiction on Brain Function and Structure of Children and Adolescents: A Scoping Review.
Ding K, Shen Y, Liu Q, Li H. Ding K, et al. Healthcare (Basel). 2023 Dec 20;12(1):15. doi: 10.3390/healthcare12010015. Healthcare (Basel). 2023. PMID: 38200921 Free PMC article. Review.
Lower synaptic density associated with gaming disorder: an ¹⁸F-SynVesT-1 PET imaging study.
Hou J, Xiao Q, Zhou M, Xiao L, Yuan M, Zhong N, Long J, Luo T, Hu S, Dong H. Hou J, et al. Gen Psychiatr. 2023 Oct 10;36(5):e101112. doi: 10.1136/gpsych-2023-101112. eCollection 2023. Gen Psychiatr. 2023. PMID: 37829163 Free PMC article.
Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions.
Mestre-Bach G, Potenza MN. Mestre-Bach G, et al. Nutrients. 2023 Feb 6;15(4):827. doi: 10.3390/nu15040827. Nutrients. 2023. PMID: 36839185 Free PMC article. Review.
Opposing associations of Internet Use Disorder symptom domains with structural and functional organization of the striatum: A dimensional neuroimaging approach.
Yu F, Li J, Xu L, Zheng X, Fu M, Li K, Yao S, Kendrick KM, Montag C, Becker B. Yu F, et al. J Behav Addict. 2022 Nov 23;11(4):1068-1079. doi: 10.1556/2006.2022.00078. Print 2022 Dec 27. J Behav Addict. 2022. PMID: 36422683 Free PMC article.

See all "Cited by" articles

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Elsevier Science

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

A selective involvement of putamen functional connectivity in youth with internet gaming disorder

Affiliations

A selective involvement of putamen functional connectivity in youth with internet gaming disorder

Authors

Affiliations

Abstract

Similar articles

Cited by

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Abstract

Similar articles

Cited by

Publication types

MeSH terms

Related information

LinkOut - more resources

Full Text Sources