The KIDROP model of combining strategies for providing retinopathy of prematurity screening in underserved areas in India using wide-field imaging, tele-medicine, non-physician graders and smart phone reporting
- PMID: 24492500
- PMCID: PMC3955069
- DOI: 10.4103/0301-4738.126178
The KIDROP model of combining strategies for providing retinopathy of prematurity screening in underserved areas in India using wide-field imaging, tele-medicine, non-physician graders and smart phone reporting
Abstract
Aim: To report the Karnataka Internet Assisted Diagnosis of Retinopathy of Prematurity (KIDROP) program for retinopathy of prematurity (ROP) screening in underserved rural areas using an indigenously developed tele-ROP model.
Materials and methods: KIDROP currently provides ROP screening and treatment services in three zones and 81 neonatal units in Karnataka, India. Technicians were trained to use a portable Retcam Shuttle (Clarity, USA) and validated against ROP experts performing indirect ophthalmoscopy. An indigenously developed 20-point score (STAT score) graded their ability (Level I to III) to image and decide follow-up based on a three-way algorithm. Images were also uploaded on a secure tele-ROP platform and accessed and reported by remote experts on their smart phones (iPhone, Apple).
Results: 6339 imaging sessions of 1601 infants were analyzed. A level III technician agreed with 94.3% of all expert decisions. The sensitivity, specificity, positive predictive value and negative predictive value for treatment grade disease were 95.7, 93.2, 81.5 and 98.6 respectively. The kappa for technicians to decide discharge of babies was 0.94 (P < 0.001). Only 0.4% of infants needing treatment were missed.The kappa agreement of experts reporting on the iPhone vs. Retcam for treatment requiring and mild ROP were 0.96 and 0.94 (P < 0.001) respectively.
Conclusions: This is the first and largest real-world program to employ accredited non-physicians to grade and report ROP. The KIDROP tele-ROP model demonstrates that ROP services can be delivered to the outreach despite lack of specialists and may be useful in other middle-income countries with similar demographics.
Conflict of interest statement
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References
-
- Gilbert C, Fielder A, Gordillo L, Quinn G, Semiglia R, Visintin P, et al. International NO-ROP Group. Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate, and high levels of development: Implications for screening programs. Pediatrics. 2005;115:e518–25. - PubMed
-
- Gilbert C. Retinopathy of Prematurity in middle-income countries. Lancet. 1997;350:12–4. - PubMed
-
- Born to Soon. The Global Action Report on Preterm Birth. United Nations. 2012. [Last accessed on 2013 Dec 31]. Available from: http://www.who.int/pmnch/media/news/2012/201204_borntoosoon-report.pdf .
-
- Report for year 2003-2004. New Delhi: 2005. National Neonatology Forum of India. National Neonatal Perinatal Database.
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