Estrogen dependent signaling in reproductive tissues - a role for estrogen receptors and estrogen related receptors
- PMID: 21964318
- DOI: 10.1016/j.mce.2011.09.026
Estrogen dependent signaling in reproductive tissues - a role for estrogen receptors and estrogen related receptors
Abstract
Estrogens play a fundamental role in the development and normal physiological function of multiple tissue systems and have been implicated in the ontogeny of cancers. The biological effects of estrogens are classically mediated via interaction with cognate nuclear receptors. The relative expression of ER subtypes/variants varies between cells within different tissues and this alters the response to natural and synthetic ligands. This review focuses on the role of estrogen and estrogen related receptors in reproductive tissues.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
Similar articles
-
Functional responses of estrogen receptors in the male and female auditory system.Hear Res. 2009 Jun;252(1-2):71-8. doi: 10.1016/j.heares.2008.12.009. Epub 2009 Jan 22. Hear Res. 2009. PMID: 19450435 Review.
-
Single-chain estrogen receptors (ERs) reveal that the ERalpha/beta heterodimer emulates functions of the ERalpha dimer in genomic estrogen signaling pathways.Mol Cell Biol. 2004 Sep;24(17):7681-94. doi: 10.1128/MCB.24.17.7681-7694.2004. Mol Cell Biol. 2004. PMID: 15314175 Free PMC article.
-
Estrogen receptors: orchestrators of pleiotropic cellular responses.EMBO Rep. 2001 Sep;2(9):775-81. doi: 10.1093/embo-reports/kve185. EMBO Rep. 2001. PMID: 11559590 Free PMC article. Review.
-
Estrogen receptor-mediated processes in normal and cancer cells.J Natl Cancer Inst Monogr. 2000;(27):135-45. doi: 10.1093/oxfordjournals.jncimonographs.a024237. J Natl Cancer Inst Monogr. 2000. PMID: 10963625 Review.
-
Estrogen receptors: bioactivities and interactions with cell signaling pathways.Biol Reprod. 1996 Feb;54(2):287-93. doi: 10.1095/biolreprod54.2.287. Biol Reprod. 1996. PMID: 8788178 Review.
Cited by
-
Estrogen-Related Receptor α: A Key Transcription Factor in the Regulation of Energy Metabolism at an Organismic Level and a Target of the ABA/LANCL Hormone Receptor System.Int J Mol Sci. 2024 Apr 27;25(9):4796. doi: 10.3390/ijms25094796. Int J Mol Sci. 2024. PMID: 38732013 Free PMC article. Review.
-
Cyclic processes in the uterine tubes, endometrium, myometrium, and cervix: pathways and perturbations.Mol Hum Reprod. 2023 Apr 29;29(5):gaad012. doi: 10.1093/molehr/gaad012. Mol Hum Reprod. 2023. PMID: 37225518 Free PMC article. Review.
-
Exploring the Potential Hormonal Effects of Tire Polymers (TPs) on Different Species Based on a Theoretical Computational Approach.Polymers (Basel). 2023 Mar 30;15(7):1719. doi: 10.3390/polym15071719. Polymers (Basel). 2023. PMID: 37050333 Free PMC article.
-
Biological effects and regulation of IGFBP5 in breast cancer.Front Endocrinol (Lausanne). 2022 Aug 25;13:983793. doi: 10.3389/fendo.2022.983793. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36093095 Free PMC article. Review.
-
Estrogen Receptors-Mediated Apoptosis in Hormone-Dependent Cancers.Int J Mol Sci. 2022 Jan 22;23(3):1242. doi: 10.3390/ijms23031242. Int J Mol Sci. 2022. PMID: 35163166 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources