Can a chronic dental infection be considered a cause of cardiovascular disease? A review of the literature
- PMID: 20851474
- DOI: 10.1016/j.ijcard.2010.08.011
Can a chronic dental infection be considered a cause of cardiovascular disease? A review of the literature
Abstract
Cardiovascular diseases (CVD) have a complex etiology determined by risk factors, which are in turn associated to a strong genetic component and to environmental factors. In the biological background for the development of CVD, low-grade chronic inflammation plays a role as a pathogenetic determinant of atherosclerosis. Dental infections have been associated with CVD. Periodontal disease is a chronic infection of the supporting tissues of the tooth that can lead to teeth loss. In recent years, a number of reports have demonstrated the possible relationship between periodontal disease and CVD. Apical periodontitis, on the other hand, is the late consequence of an endodontic infection, which is caused by the persistence of coronal caries and involves the root canal system of the tooth. Most of the time, it is a chronic infection. Some studies have found a correlation between a "composite status" of oral health (eg. caries, tooth loss, periodontal disease) and CVD, but only a few of them have addressed the association between apical periodontitis and CVD. This "state of the art" paper represents the first stage of an incoming study on the relationship between chronic endodontic infection and CVD.
Copyright © 2010 Published by Elsevier Ireland Ltd.
Similar articles
-
Dental infection and vascular disease.Semin Thromb Hemost. 2011 Apr;37(3):181-92. doi: 10.1055/s-0031-1273082. Epub 2011 Mar 31. Semin Thromb Hemost. 2011. PMID: 21455852 Review.
-
Association of Radiographically Diagnosed Apical Periodontitis and Cardiovascular Disease: A Hospital Records-based Study.J Endod. 2016 Jun;42(6):916-20. doi: 10.1016/j.joen.2016.03.011. Epub 2016 Apr 16. J Endod. 2016. PMID: 27091354
-
Diabetes, periodontal diseases, dental caries, and tooth loss: a review of the literature.Compend Contin Educ Dent. 2004 Mar;25(3):179-84, 186-8, 190; quiz 192. Compend Contin Educ Dent. 2004. PMID: 15641324 Review.
-
Periodontal disease as a risk factor for cardiovascular disease: suggestion of a further link in systemic lupus erythematosus.Med Hypotheses. 2011 Aug;77(2):286-9. doi: 10.1016/j.mehy.2011.04.037. Epub 2011 May 23. Med Hypotheses. 2011. PMID: 21601991 Review.
-
Periodontal infections and cardiovascular disease: is it a mere association?Kathmandu Univ Med J (KUMJ). 2006 Jul-Sep;4(3):379-82. Kathmandu Univ Med J (KUMJ). 2006. PMID: 18603938 Review.
Cited by
-
Association of Dental Diseases and Oral Hygiene Care With the Risk of Heart Failure in Patients With Type 2 Diabetes: A Nationwide Cohort Study.J Am Heart Assoc. 2023 Aug 15;12(16):e029207. doi: 10.1161/JAHA.122.029207. Epub 2023 Aug 7. J Am Heart Assoc. 2023. PMID: 37548156 Free PMC article.
-
Interaction between apical periodontitis and systemic disease (Review).Int J Mol Med. 2023 Jul;52(1):60. doi: 10.3892/ijmm.2023.5263. Epub 2023 Jun 2. Int J Mol Med. 2023. PMID: 37264964 Free PMC article. Review.
-
Oral Microbiota, Its Equilibrium and Implications in the Pathophysiology of Human Diseases: A Systematic Review.Biomedicines. 2022 Jul 27;10(8):1803. doi: 10.3390/biomedicines10081803. Biomedicines. 2022. PMID: 36009350 Free PMC article. Review.
-
Effect of Fraxetin on Oxidative Damage Caused by Isoproterenol-Induced Myocardial Infarction in Rats.Appl Biochem Biotechnol. 2022 Dec;194(12):5666-5679. doi: 10.1007/s12010-022-04019-y. Epub 2022 Jul 8. Appl Biochem Biotechnol. 2022. PMID: 35802243
-
Chronic Endodontic Infections and Cardiovascular Diseases: Does the Evidence Support an Independent Association?Cureus. 2021 Nov 24;13(11):e19864. doi: 10.7759/cureus.19864. eCollection 2021 Nov. Cureus. 2021. PMID: 34976491 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
