No evidence of large differences in mother-daughter and father-son body mass index concordance in a large UK birth cohort
- PMID: 20351737
- DOI: 10.1038/ijo.2010.60
No evidence of large differences in mother-daughter and father-son body mass index concordance in a large UK birth cohort
Abstract
It has recently been suggested that there are substantial differences in mother-daughter and father-son associations of body mass index and obesity among contemporary UK children, but much larger studies of older cohorts have failed to find evidence of substantial sex-specific effects. We have tested this hypothesis using the Avon Longitudinal Study of Parents and Children, a large contemporary cohort. Our analyses are based on 4654 complete parent-offspring trios (2323 with male offspring and 2331 with female offspring, all aged approximately 7.5 years). We found maternal body mass index to be a little more strongly associated with female than with male offspring body mass index (beta=0.18 (95% confidence interval 0.16-0.20) for females vs 0.13 (0.12, 0.15) for males). However, associations between paternal body mass index and male compared with female offspring were very similar (beta=0.16 (0.14, 0.19) for females vs 0.15 (0.12, 0.17) for males). Hence, our study suggests that there is no compelling reason to integrate the belief that there are large differences in parent-offspring body mass index associations with obesity prevention strategies.
Comment in
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Gender-assortative weight gain: reply to Leary, Smith and Ness.Int J Obes (Lond). 2011 Jan;35(1):150; author reply 151-2. doi: 10.1038/ijo.2010.167. Epub 2010 Sep 21. Int J Obes (Lond). 2011. PMID: 20856252 No abstract available.
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