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. 2010 Jul;94(2):781-3.e1.
doi: 10.1016/j.fertnstert.2009.10.020. Epub 2009 Nov 25.

Epigenetics in polycystic ovary syndrome: a pilot study of global DNA methylation

Ning Xu  1 , Ricardo Azziz, Mark O Goodarzi
Affiliations

Epigenetics in polycystic ovary syndrome: a pilot study of global DNA methylation

Ning Xu et al. Fertil Steril. 2010 Jul.

Abstract

The percent global methylation of peripheral blood DNA was not significantly altered in 20 women with polycystic ovary syndrome (PCOS) compared with 20 controls. The study of specific tissues and target genomic regions will be required to further determine whether epigenetic alteration influences the development of PCOS.

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Figures

Figure 1
Figure 1
Percent methylation box plots. Controls are represented in blue, PCOS subjects in red. For each group, the bottom and top bars indicate the 10th and 90th percentiles. The bottom and top of each box indicate the 25th and 75th percentiles, and the line in the middle of each box is the median.
See this image and copyright information in PMC

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