Retrotransposons revisited: the restraint and rehabilitation of parasites
- PMID: 18854152
- DOI: 10.1016/j.cell.2008.09.022
Retrotransposons revisited: the restraint and rehabilitation of parasites
Abstract
Retrotransposons, mainly LINEs, SINEs, and endogenous retroviruses, make up roughly 40% of the mammalian genome and have played an important role in genome evolution. Their prevalence in genomes reflects a delicate balance between their further expansion and the restraint imposed by the host. In any human genome only a small number of LINE1s (L1s) are active, moving their own and SINE sequences into new genomic locations and occasionally causing disease. Recent insights and new technologies promise answers to fundamental questions about the biology of transposable elements.
Similar articles
-
LINEs, SINEs and processed pseudogenes: parasitic strategies for genome modeling.Cytogenet Genome Res. 2005;110(1-4):35-48. doi: 10.1159/000084936. Cytogenet Genome Res. 2005. PMID: 16093656 Review.
-
[Non-LTR retrotransposons: LINEs and SINEs in plant genome].Yi Chuan. 2006 Jun;28(6):731-6. Yi Chuan. 2006. PMID: 16818439 Review. Chinese.
-
Retrofitting the genome: L1 extinction follows endogenous retroviral expansion in a group of muroid rodents.J Virol. 2011 Dec;85(23):12315-23. doi: 10.1128/JVI.05180-11. Epub 2011 Sep 28. J Virol. 2011. PMID: 21957310 Free PMC article.
-
Expression of Retroelements in Mammalian Gametes and Embryos.In Vivo. 2021 Jul-Aug;35(4):1921-1927. doi: 10.21873/invivo.12458. In Vivo. 2021. PMID: 34182464 Free PMC article. Review.
-
Origin and evolution of LINE-1 derived "half-L1" retrotransposons (HAL1).Gene. 2010 Oct 1;465(1-2):9-16. doi: 10.1016/j.gene.2010.06.005. Epub 2010 Jun 21. Gene. 2010. PMID: 20600705 Free PMC article.
Cited by
-
Effects of Arboviral Infections on Transposable Element Transcript Levels in Aedes aegypti.Genome Biol Evol. 2024 May 2;16(5):evae092. doi: 10.1093/gbe/evae092. Genome Biol Evol. 2024. PMID: 38695057 Free PMC article.
-
Dissolution of ribonucleoprotein condensates by the embryonic stem cell protein L1TD1.Nucleic Acids Res. 2024 Apr 12;52(6):3310-3326. doi: 10.1093/nar/gkad1244. Nucleic Acids Res. 2024. PMID: 38165001 Free PMC article.
-
Regulation potential of transcribed simple repeated sequences in developing neurons.Hum Genet. 2023 Dec 28. doi: 10.1007/s00439-023-02626-1. Online ahead of print. Hum Genet. 2023. PMID: 38153590
-
SINE-Associated LncRNA SAWPA Regulates Porcine Zygotic Genome Activation.Adv Sci (Weinh). 2024 Jan;11(2):e2307505. doi: 10.1002/advs.202307505. Epub 2023 Nov 20. Adv Sci (Weinh). 2024. PMID: 37984872 Free PMC article.
-
Sequencing and Characterization of αs2-Casein Gene (CSN1S2) in the Old-World Camels Have Proven Genetic Variations Useful for the Understanding of Species Diversification.Animals (Basel). 2023 Sep 4;13(17):2805. doi: 10.3390/ani13172805. Animals (Basel). 2023. PMID: 37685069 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources