Syncope after vaccination--United States, January 2005-July 2007
- PMID: 18451756
Syncope after vaccination--United States, January 2005-July 2007
Abstract
Syncope (vasovagal reaction), or fainting, can be triggered by various stimuli, including medical procedures. Syncope has been documented to occur after vaccination, most commonly among adolescents, and can result in hospitalization for a medical evaluation or because of injury. During 2005 and 2006, the Advisory Committee on Immunization Practices (ACIP) recommended use of three newly licensed vaccines for adolescents: the quadrivalent human papillomavirus recombinant vaccine (HPV) (Gardasil(R), Merck & Co., Inc., Whitehouse Station, New Jersey) in a 3-dose series, the quadrivalent meningococcal conjugate vaccine (MCV4) (Menactra, Sanofi Pasteur, Inc., Swiftwater, Pennsylvania) in a single dose, and the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) (Adacel, Sanofi Pasteur; Boostrix, GlaxoSmithKline Biologicals, Research Triangle Park, North Carolina) in a single dose. To describe trends in occurrence of postvaccination syncope, CDC and the Food and Drug Administration (FDA) analyzed data from the Vaccine Adverse Event Reporting System (VAERS) for January 1, 2005-July 31, 2007, and compared the results with VAERS reports received during January 1, 2002-December 31, 2004. The findings indicated that, since 2005, reports to VAERS regarding postvaccination syncope have increased, primarily among females aged 11-18 years, and rarely, subsequent serious injuries have occurred. To prevent syncope-related injuries, vaccine providers should follow the ACIP recommendation to strongly consider observing patients for 15 minutes after vaccination.
Similar articles
-
Prevention of pertussis among adolescents: recommendations for use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine.Pediatrics. 2006 Mar;117(3):965-78. doi: 10.1542/peds.2005-3038. Epub 2005 Dec 28. Pediatrics. 2006. PMID: 16382131
-
Preventing tetanus, diphtheria, and pertussis among adolescents: use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccines recommendations of the Advisory Committee on Immunization Practices (ACIP).MMWR Recomm Rep. 2006 Mar 24;55(RR-3):1-34. MMWR Recomm Rep. 2006. PMID: 16557217
-
Guillain-Barré syndrome among recipients of Menactra meningococcal conjugate vaccine--United States, June-July 2005.MMWR Morb Mortal Wkly Rep. 2005 Oct 14;54(40):1023-5. MMWR Morb Mortal Wkly Rep. 2005. PMID: 16224452
-
Use of MenACWY-CRM in adolescents in the United States.J Adolesc Health. 2013 Mar;52(3):271-7. doi: 10.1016/j.jadohealth.2012.07.017. Epub 2012 Sep 25. J Adolesc Health. 2013. PMID: 23299001 Review.
-
Use of meningococcal vaccines in the United States.Pediatr Infect Dis J. 2007 May;26(5):371-6. doi: 10.1097/01.inf.0000259996.95965.ef. Pediatr Infect Dis J. 2007. PMID: 17468644 Review.
Cited by
-
Safety profile assessment of HPV4 and HPV9 vaccines through the passive surveillance system of the Veneto Region (Italy) between 2008 and 2022: A 15-year retrospective observational study.Vaccine X. 2024 Jun 21;19:100511. doi: 10.1016/j.jvacx.2024.100511. eCollection 2024 Aug. Vaccine X. 2024. PMID: 39040889 Free PMC article.
-
The clinical effectiveness of one-dose vaccination with an HPV vaccine: A meta-analysis of 902,368 vaccinated women.PLoS One. 2024 Jan 5;19(1):e0290808. doi: 10.1371/journal.pone.0290808. eCollection 2024. PLoS One. 2024. PMID: 38180991 Free PMC article.
-
Incidence of Adolescent Syncope and Related Injuries Following Vaccination and Routine Venipuncture.J Adolesc Health. 2024 Apr;74(4):696-702. doi: 10.1016/j.jadohealth.2023.11.005. Epub 2023 Dec 9. J Adolesc Health. 2024. PMID: 38069938
-
Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine.Cureus. 2023 Jan 28;15(1):e34309. doi: 10.7759/cureus.34309. eCollection 2023 Jan. Cureus. 2023. PMID: 36860236 Free PMC article.
-
Introducing CARD (Comfort Ask Relax Distract) as a vaccine delivery program for community pharmacy-based vaccinations.Can Pharm J (Ott). 2022 Dec 13;156(1 Suppl):2S-5S. doi: 10.1177/17151635221136489. eCollection 2023 Jan-Feb. Can Pharm J (Ott). 2022. PMID: 36756629 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical