Relationship of metabolic risk factors and development of cardiovascular disease and diabetes
- PMID: 16931493
- DOI: 10.1038/oby.2006.291
Relationship of metabolic risk factors and development of cardiovascular disease and diabetes
Abstract
The prevalence of obesity and diabetes has reached pandemic proportions. Obesity, particularly in association with high waist circumference and high BMI, is an independent risk factor for coronary heart disease (CHD) and diabetes. Several large studies have shown that marginal (5 lb) to moderate (11 to 22 lb) weight gain in adulthood (age 20 to 50 years) increases the risk of chronic disease and negatively affects CHD risk status. The metabolic syndrome, a clustering of cardiovascular and metabolic risk factors that includes abdominal obesity, is increasing among adults and children and is strongly associated with the development of diabetes and CHD. Recent evidence suggests that elevated liver enzymes, an indicator of non-alcoholic fatty liver disease, may comprise an additional component of the metabolic syndrome and may serve as a surrogate marker for type 2 diabetes, particularly if used in conjunction with C-reactive protein.
Similar articles
-
Abdominal obesity, waist circumference and cardio-metabolic risk: awareness among primary care physicians, the general population and patients at risk--the Shape of the Nations survey.Curr Med Res Opin. 2007 Jan;23(1):29-47. doi: 10.1185/030079906X159489. Curr Med Res Opin. 2007. PMID: 17261236
-
What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?J Gastroenterol Hepatol. 2007 Jun;22(6):794-800. doi: 10.1111/j.1440-1746.2007.04952.x. Epub 2007 May 13. J Gastroenterol Hepatol. 2007. PMID: 17498218
-
Type 2 diabetes mellitus: a high-risk condition for cardiovascular disease irrespective of the different degrees of obesity.QJM. 2008 Nov;101(11):875-9. doi: 10.1093/qjmed/hcn109. Epub 2008 Sep 6. QJM. 2008. PMID: 18776208
-
The cardiometabolic syndrome in the adolescent.Pediatr Endocrinol Rev. 2008 Aug;5 Suppl 4:964-8. Pediatr Endocrinol Rev. 2008. PMID: 18806711 Review.
-
Increasing prevalence of obesity and clustered cardiometabolic risk: can treatment of the underlying cause reverse the trends?Crit Pathw Cardiol. 2007 Jun;6(2):41-5. doi: 10.1097/HPC.0b013e318053d190. Crit Pathw Cardiol. 2007. PMID: 17667863 Review.
Cited by
-
Association of the triglyceride-glucose index with all-cause and cardiovascular mortality in patients with cardiometabolic syndrome: a national cohort study.Cardiovasc Diabetol. 2024 Feb 24;23(1):80. doi: 10.1186/s12933-024-02152-y. Cardiovasc Diabetol. 2024. PMID: 38402393 Free PMC article.
-
Prevalence and related factors of abdominal obesity among urban adults aged 35 to 79 years in southwest China.Front Public Health. 2023 Nov 8;11:1117897. doi: 10.3389/fpubh.2023.1117897. eCollection 2023. Front Public Health. 2023. PMID: 38026354 Free PMC article.
-
Cardiovascular disease and risk factors in adults with diabetes mellitus in Hungary: a population-based study.Front Endocrinol (Lausanne). 2023 Sep 14;14:1263365. doi: 10.3389/fendo.2023.1263365. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37780630 Free PMC article.
-
Neo-Traditional and Industrialized Dietary Patterns Coexist and Are Differentially Associated with Cardiometabolic Health among Adults in Puerto Rico.J Nutr. 2023 Nov;153(11):3259-3269. doi: 10.1016/j.tjnut.2023.09.003. Epub 2023 Sep 9. J Nutr. 2023. PMID: 37689268
-
Stakeholder-led understanding of the implementation of digital technologies within heart disease diagnosis: a qualitative study protocol.BMJ Open. 2023 Jun 27;13(6):e072952. doi: 10.1136/bmjopen-2023-072952. BMJ Open. 2023. PMID: 37369399 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials
