Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 Nov;59(11):1133-50.
doi: 10.1136/jcp.2005.031260. Epub 2006 May 5.

An approach to duodenal biopsies

S Serra  1 , P A Jani
Affiliations
Review

An approach to duodenal biopsies

S Serra et al. J Clin Pathol. 2006 Nov.

Abstract

The introduction of endoscopy of the upper digestive tract as a routine diagnostic procedure has increased the number of duodenal biopsy specimens. Consequently, the pathologist is often asked to evaluate them. In this review, a practical approach to the evaluation of a duodenal biopsy specimen is discussed. An overview of the handling of specimens is given and the normal histology and commonly encountered diseases are discussed. Finally, a description of commonly seen infections is provided, together with an algorithmic approach for diagnosis.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Anon Normal embryology and fetal development. In: Morson and Dawson's gastrointestinal pathology. 4th edn. Blackwell Publishing 2003252–254.
    1. Kori M, Gladish V, Ziv‐Sokolovskaya N.et al The significance of routine duodenal biopsies in pediatric patients undergoing upper intestinal endoscopy. J Clin Gastroenterol 20033739–41. - PubMed
    1. Hopper A D, Cross S S, McAlindon M E.et al Symptomatic giardiasis without diarrhea: further evidence to support the routine duodenal biopsy? Gastrointest Endosc 200358120–122. - PubMed
    1. Shidrawi R G, Przemioslo R, Davies D R.et al Pitfalls in diagnosing coeliac disease. J Clin Pathol 199447693–694. - PMC - PubMed
    1. Ravelli A, Bolognini S, Gambarotti M.et al Variability of histologic lesions in relation to biopsy site in gluten‐sensitive enteropathy. Am J Gastroenterol 2005100177–185. - PubMed