Neurobiochemical and clinical aspects of craving in alcohol addiction: a review
- PMID: 15925129
- DOI: 10.1016/j.addbeh.2004.12.011
Neurobiochemical and clinical aspects of craving in alcohol addiction: a review
Abstract
Craving plays an important role in the pathogenesis of alcohol dependence and relapse. In this review we have tried to analyse how many contrasting theories have been formulated in order to clarify the concept of craving. Many complex neurobiochemical mechanisms are implicated in the etiology of craving; these mechanisms involve several neurotransmitters, such us dopamine, opioids, glutamate, and serotonin. On the other hand comportamental and/or cognitive aspects could also play a role in the etiology of craving. The coexistence of many and often contrasting theories can indicate that different subtypes of patients could have different mechanisms at the basis of alcohol craving, suggesting that it could be advisable to personalize the anti-craving therapy.
Similar articles
-
Clinical and laboratory assessment of the subjective experience of drug craving.Clin Psychol Rev. 2009 Aug;29(6):519-34. doi: 10.1016/j.cpr.2009.06.002. Epub 2009 Jun 11. Clin Psychol Rev. 2009. PMID: 19577831 Review.
-
Association of the long allele of the 5-HTTLPR polymorphism with compulsive craving in alcohol dependence.Alcohol Alcohol. 2007 Nov-Dec;42(6):509-12. doi: 10.1093/alcalc/agm068. Epub 2007 Aug 21. Alcohol Alcohol. 2007. PMID: 17711874
-
Alcohol craving scale based on three factors.Eur Addict Res. 2009;15(3):135-42. doi: 10.1159/000210043. Epub 2009 Mar 31. Eur Addict Res. 2009. PMID: 19332992
-
Impact of craving on alcohol relapse during, and 12 months following, outpatient treatment.Alcohol Alcohol. 2004 Jul-Aug;39(4):357-61. doi: 10.1093/alcalc/agh073. Alcohol Alcohol. 2004. PMID: 15208171
-
Animal models of obsessive-compulsive disorder: rationale to understanding psychobiology and pharmacology.Psychiatr Clin North Am. 2006 Jun;29(2):371-90. doi: 10.1016/j.psc.2006.02.007. Psychiatr Clin North Am. 2006. PMID: 16650714 Review.
Cited by
-
Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies.Mol Psychiatry. 2022 Nov;27(11):4642-4652. doi: 10.1038/s41380-022-01736-y. Epub 2022 Sep 20. Mol Psychiatry. 2022. PMID: 36123420 Free PMC article.
-
Cyclic Nucleotide Phosphodiesterases in Alcohol Use Disorders: Involving Gut Microbiota.Int J Neuropsychopharmacol. 2023 Jan 19;26(1):70-79. doi: 10.1093/ijnp/pyac060. Int J Neuropsychopharmacol. 2023. PMID: 36087271 Free PMC article.
-
Effects of 10 add-on HF-rTMS treatment sessions on alcohol use and craving among detoxified inpatients with alcohol use disorder: a randomized sham-controlled clinical trial.Addiction. 2023 Jan;118(1):71-85. doi: 10.1111/add.16025. Epub 2022 Sep 7. Addiction. 2023. PMID: 35971295 Free PMC article. Clinical Trial.
-
Preventive Effects of Baclofen but Not Diazepam on Hippocampal Memory and Glucocorticoid Alterations After Prolonged Alcohol Withdrawal in Mice.Front Psychiatry. 2022 May 24;13:799225. doi: 10.3389/fpsyt.2022.799225. eCollection 2022. Front Psychiatry. 2022. PMID: 35686185 Free PMC article.
-
Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients.Gut Microbes. 2022 Jan-Dec;14(1):2007042. doi: 10.1080/19490976.2021.2007042. Gut Microbes. 2022. PMID: 34923905 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
