The US smallpox vaccination program: a review of a large modern era smallpox vaccination implementation program
- PMID: 15755574
- DOI: 10.1016/j.vaccine.2005.01.012
The US smallpox vaccination program: a review of a large modern era smallpox vaccination implementation program
Abstract
We describe the US experience with a large-scale smallpox vaccination program in the modern era and quantify the anticipated and unanticipated local and systemic side-effects of smallpox vaccination. In addition, we review unexpected issues, such as the development of myopericarditis discovered during the implementation of this program. These results constitute the largest dataset of a vaccinia vaccination program utilizing calf-lymph derived New York City Board of Health strain vaccine (Dryvax, Wyeth) since the 1970s. These results should inform current and future vaccinia vaccination programs and provide a historical rate of complications against which candidate vaccine side-effects can be compared in future clinical trials.
Similar articles
-
Monitoring the safety of a smallpox vaccination program in the United States: report of the joint Smallpox Vaccine Safety Working Group of the advisory committee on immunization practices and the Armed Forces Epidemiological Board.Clin Infect Dis. 2008 Mar 15;46 Suppl 3:S258-70. doi: 10.1086/524749. Clin Infect Dis. 2008. PMID: 18284367
-
Myocarditis, pericarditis, and dilated cardiomyopathy after smallpox vaccination among civilians in the United States, January-October 2003.Clin Infect Dis. 2008 Mar 15;46 Suppl 3:S242-50. doi: 10.1086/524747. Clin Infect Dis. 2008. PMID: 18284365
-
US Civilian Smallpox Preparedness and Response Program, 2003.Clin Infect Dis. 2008 Mar 15;46 Suppl 3:S157-67. doi: 10.1086/524751. Clin Infect Dis. 2008. PMID: 18284355
-
Smallpox vaccination and myopericarditis: a clinical review.J Am Coll Cardiol. 2004 May 5;43(9):1503-10. doi: 10.1016/j.jacc.2003.11.053. J Am Coll Cardiol. 2004. PMID: 15120802 Review.
-
Pregnancy discovered after smallpox vaccination: Is vaccinia immune globulin appropriate?Am J Obstet Gynecol. 2004 Dec;191(6):1863-7. doi: 10.1016/j.ajog.2004.07.014. Am J Obstet Gynecol. 2004. PMID: 15592266 Review.
Cited by
-
Repositioning potentials of smallpox vaccines and antiviral agents in monkeypox outbreak: A rapid review on comparative benefits and risks.Health Sci Rep. 2022 Aug 23;5(5):e798. doi: 10.1002/hsr2.798. eCollection 2022 Sep. Health Sci Rep. 2022. PMID: 36032515 Free PMC article.
-
Low-Temperature Multiple Micro-Dispensing on Microneedles for Accurate Transcutaneous Smallpox Vaccination.Vaccines (Basel). 2022 Apr 4;10(4):561. doi: 10.3390/vaccines10040561. Vaccines (Basel). 2022. PMID: 35455310 Free PMC article.
-
Interferon α/β Decoy Receptor Encoded by a Variant in the Dryvax Smallpox Vaccine Contributes to Virulence and Correlates with Severe Vaccine Side Effects.mBio. 2022 Feb 22;13(1):e0010222. doi: 10.1128/mbio.00102-22. Epub 2022 Feb 22. mBio. 2022. PMID: 35189701 Free PMC article.
-
Epidemiological Impact of Myocarditis.J Clin Med. 2021 Feb 5;10(4):603. doi: 10.3390/jcm10040603. J Clin Med. 2021. PMID: 33562759 Free PMC article. Review.
-
Are We Prepared in Case of a Possible Smallpox-Like Disease Emergence?Viruses. 2017 Aug 27;9(9):242. doi: 10.3390/v9090242. Viruses. 2017. PMID: 32962316 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
