Salivary cortisol concentrations are associated with acute nicotine withdrawal
- PMID: 15451136
- DOI: 10.1016/j.addbeh.2004.02.059
Salivary cortisol concentrations are associated with acute nicotine withdrawal
Abstract
Research has shown that smoking commercial cigarettes results in slight elevations in cortisol levels relative to smoking nicotine-free cigarettes. It is not clear however, whether cortisol concentrations are associated with nicotine withdrawal symptoms among regular cigarette smokers. Nicotine withdrawal symptoms resemble a stress response, and may therefore contribute to cortisol production. This preliminary study focuses on assessing the association between salivary cortisol levels and subsequent levels of self-reported withdrawal and craving symptoms. Twenty male smokers were studied during a 4-h deprivation period. All participants smoked an initial cigarette shortly after arrival and were informed that they would be unable to smoke for the remainder of the session. The session consisted of each participant watching a movie, and then waiting in the laboratory for two consecutive 30-min intervals. Self-reported nicotine withdrawal and craving were assessed four times and salivary cortisol, five times, during the session. Results show that baseline cortisol concentrations predicted subsequent withdrawal symptoms and craving measured using the Tobacco Withdrawal Symptom Checklist (WSC). This suggests that salivary cortisol may contribute to, or be a marker of, nicotine withdrawal symptoms.
Similar articles
-
Smokers deprived of cigarettes for 72 h: effect of nicotine patches on craving and withdrawal.Psychopharmacology (Berl). 2002 Nov;164(2):177-87. doi: 10.1007/s00213-002-1176-1. Epub 2002 Aug 27. Psychopharmacology (Berl). 2002. PMID: 12404080 Clinical Trial.
-
Multimodal assessment of the effect of chewing gum on nicotine withdrawal.Addict Behav. 2001 Mar-Apr;26(2):289-95. doi: 10.1016/s0306-4603(00)00100-3. Addict Behav. 2001. PMID: 11316385
-
Effect of nicotine lozenges on affective smoking withdrawal symptoms: secondary analysis of a randomized, double-blind, placebo-controlled clinical trial.Clin Ther. 2008 Aug;30(8):1461-75. doi: 10.1016/j.clinthera.2008.07.019. Clin Ther. 2008. PMID: 18803988 Clinical Trial.
-
Nicotine, corticotropin, and smoking withdrawal symptoms: literature review and implications for successful control of nicotine addiction.Clin Ther. 1989 Nov-Dec;11(6):846-53. Clin Ther. 1989. PMID: 2558798 Review.
-
Bupropion for the treatment of nicotine withdrawal and craving.Expert Rev Neurother. 2006 Jul;6(7):965-81. doi: 10.1586/14737175.6.7.965. Expert Rev Neurother. 2006. PMID: 16831112 Review.
Cited by
-
Methylation of the Oxytocin, Oxytocin Receptor, and Vasopressin Gene Promoters in Tobacco Use Disorder during Cessation.Neuropsychobiology. 2024;83(1):28-40. doi: 10.1159/000535663. Epub 2024 Jan 5. Neuropsychobiology. 2024. PMID: 38185116 Free PMC article.
-
Can Psychosocial Intervention Suppress Testosterone and Triglycerides Among Women With Polycystic Ovary Syndrome? A Feasibility Trial.Front Psychol. 2021 Jul 22;12:690539. doi: 10.3389/fpsyg.2021.690539. eCollection 2021. Front Psychol. 2021. PMID: 34367014 Free PMC article.
-
Salivary Cortisol Levels Are Associated with Craving and Cognitive Performance in Cocaine-Abstinent Subjects: A Pilot Study.Brain Sci. 2020 Sep 27;10(10):682. doi: 10.3390/brainsci10100682. Brain Sci. 2020. PMID: 32992573 Free PMC article.
-
Drug-induced stress responses and addiction risk and relapse.Neurobiol Stress. 2019 Feb 1;10:100148. doi: 10.1016/j.ynstr.2019.100148. eCollection 2019 Feb. Neurobiol Stress. 2019. PMID: 30937354 Free PMC article. Review.
-
Cognitive-behavioral therapy improves weight loss and quality of life in women with polycystic ovary syndrome: a pilot randomized clinical trial.Fertil Steril. 2018 Jul 1;110(1):161-171.e1. doi: 10.1016/j.fertnstert.2018.03.028. Epub 2018 Jun 13. Fertil Steril. 2018. PMID: 29908771 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
