Sexual dysfunction associated with antidepressant drugs
- PMID: 15335301
- DOI: 10.1517/14740338.3.5.457
Sexual dysfunction associated with antidepressant drugs
Abstract
The term 'sexual dysfunction' describes a disturbance in sexual desire and the psychophysiological changes that characterise the normal sexual response cycle, and cause marked personal distress and interpersonal difficulty. Epidemiological studies indicate that sexual dysfunction is common in the general population, but more common in depressed individuals in community settings and clinical samples. Most antidepressant drugs have adverse effects on sexual function, but accurate identification of the incidence of treatment-emergent dysfunction has proved troublesome. Futhermore, investigations of sexual dysfunction associated with antidepressants have one or more methodological flaws. There may be some advantages for bupropion, moclobemide, nefazodone and reboxetine over other antidepressants. Many approaches have been adopted for management of patients with sexual dysfunction associated with antidepressant treatment, including waiting for the problem to resolve, behavioural strategies to modify sexual technique, individual and couple psychotherapy, delaying the intake of antidepressants until after sexual activity, reduction in daily dosage, 'drug holidays', use of adjuvant treatments, and switching to a different antidepressant.
Similar articles
-
Strategies for managing antidepressant-induced sexual dysfunction: a review.Curr Psychiatry Rep. 2006 Dec;8(6):431-6. doi: 10.1007/s11920-006-0047-6. Curr Psychiatry Rep. 2006. PMID: 17094922 Review.
-
Antidepressant-related erectile dysfunction: management via avoidance, switching antidepressants, antidotes, and adaptation.J Clin Psychiatry. 2003;64 Suppl 10:11-9. J Clin Psychiatry. 2003. PMID: 12971811 Review.
-
Strategies for managing sexual dysfunction induced by antidepressant medication.Cochrane Database Syst Rev. 2013 May 31;(5):CD003382. doi: 10.1002/14651858.CD003382.pub3. Cochrane Database Syst Rev. 2013. PMID: 23728643 Review.
-
Antidepressant-induced orgasm disorder.J Sex Marital Ther. 1995 Fall;21(3):192-201. doi: 10.1080/00926239508404398. J Sex Marital Ther. 1995. PMID: 7500370 Review.
-
Male sexual side effects associated with antidepressants: a descriptive clinical study of 32 patients.Int J Psychiatry Med. 1995;25(2):191-201. doi: 10.2190/1DHU-Y7L7-9GKG-V7WV. Int J Psychiatry Med. 1995. PMID: 7591493
Cited by
-
Natural Products Inhibitors of Monoamine Oxidases-Potential New Drug Leads for Neuroprotection, Neurological Disorders, and Neuroblastoma.Molecules. 2022 Jul 4;27(13):4297. doi: 10.3390/molecules27134297. Molecules. 2022. PMID: 35807542 Free PMC article. Review.
-
Addressing the Side Effects of Contemporary Antidepressant Drugs: A Comprehensive Review.Chonnam Med J. 2018 May;54(2):101-112. doi: 10.4068/cmj.2018.54.2.101. Epub 2018 May 25. Chonnam Med J. 2018. PMID: 29854675 Free PMC article. Review.
-
Women's sexual dysfunction associated with psychiatric disorders and their treatment.Womens Health (Lond). 2018 Jan-Dec;14:1745506518762664. doi: 10.1177/1745506518762664. Womens Health (Lond). 2018. PMID: 29649948 Free PMC article.
-
The impact of severe mental disorders and psychotropic medications on sexual health and its implications for clinical management.World Psychiatry. 2018 Feb;17(1):3-11. doi: 10.1002/wps.20509. World Psychiatry. 2018. PMID: 29352532 Free PMC article.
-
Erectile dysfunction and quality of life in men receiving methadone or buprenorphine maintenance treatment. A cross-sectional multicentre study.PLoS One. 2017 Nov 30;12(11):e0188994. doi: 10.1371/journal.pone.0188994. eCollection 2017. PLoS One. 2017. PMID: 29190831 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical