The statistical analysis of circadian phase and amplitude in constant-routine core-temperature data
- PMID: 1421473
- DOI: 10.1177/074873049200700301
The statistical analysis of circadian phase and amplitude in constant-routine core-temperature data
Abstract
Accurate estimation of the phases and amplitude of the endogenous circadian pacemaker from constant-routine core-temperature series is crucial for making inferences about the properties of the human biological clock from data collected under this protocol. This paper presents a set of statistical methods based on a harmonic-regression-plus-correlated-noise model for estimating the phases and the amplitude of the endogenous circadian pacemaker from constant-routine core-temperature data. The methods include a Bayesian Monte Carlo procedure for computing the uncertainty in these circadian functions. We illustrate the techniques with a detailed study of a single subject's core-temperature series and describe their relationship to other statistical methods for circadian data analysis. In our laboratory, these methods have been successfully used to analyze more than 300 constant routines and provide a highly reliable means of extracting phase and amplitude information from core-temperature data.
Similar articles
-
Getting through to circadian oscillators: why use constant routines?J Biol Rhythms. 2002 Feb;17(1):4-13. doi: 10.1177/074873002129002294. J Biol Rhythms. 2002. PMID: 11837947 Review.
-
A statistical model of the human core-temperature circadian rhythm.Am J Physiol Endocrinol Metab. 2000 Sep;279(3):E669-83. doi: 10.1152/ajpendo.2000.279.3.E669. Am J Physiol Endocrinol Metab. 2000. PMID: 10950837
-
Statistical model building and model criticism for human circadian data.J Biol Rhythms. 1999 Dec;14(6):609-16. doi: 10.1177/074873099129000975. J Biol Rhythms. 1999. PMID: 10643759 Clinical Trial.
-
Revised limit cycle oscillator model of human circadian pacemaker.J Biol Rhythms. 1999 Dec;14(6):493-9. doi: 10.1177/074873049901400608. J Biol Rhythms. 1999. PMID: 10643746 Review.
-
Melatonin rhythm observed throughout a three-cycle bright-light stimulus designed to reset the human circadian pacemaker.J Biol Rhythms. 1999 Jun;14(3):237-53. doi: 10.1177/074873099129000560. J Biol Rhythms. 1999. PMID: 10452336
Cited by
-
A perspective on the Festschrift of Charles A. Czeisler, PhD MD.Sleep Health. 2024 Feb;10(1S):S4-S10. doi: 10.1016/j.sleh.2024.01.003. Epub 2024 Feb 7. Sleep Health. 2024. PMID: 38331654 No abstract available.
-
Sleep-independent circadian rhythm of aldosterone secretion in healthy young adults.Sleep Health. 2024 Feb;10(1S):S103-S107. doi: 10.1016/j.sleh.2023.10.019. Epub 2023 Dec 7. Sleep Health. 2024. PMID: 38065818
-
Diurnal rhythms of wrist temperature are associated with future disease risk in the UK Biobank.Nat Commun. 2023 Aug 24;14(1):5172. doi: 10.1038/s41467-023-40977-5. Nat Commun. 2023. PMID: 37620332 Free PMC article.
-
Efficient assessment of real-world dynamics of circadian rhythms in heart rate and body temperature from wearable data.J R Soc Interface. 2023 Aug;20(205):20230030. doi: 10.1098/rsif.2023.0030. Epub 2023 Aug 23. J R Soc Interface. 2023. PMID: 37608712
-
Circadian acclimatization of performance, sleep, and 6-sulfatoxymelatonin using multiple phase shifting stimuli.Front Endocrinol (Lausanne). 2022 Nov 16;13:964681. doi: 10.3389/fendo.2022.964681. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36465660 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources