Review
doi: 10.1038/35094500.
Searching for a baseline: functional imaging and the resting human brain
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- PMID: 11584306
- DOI: 10.1038/35094500
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Review
Searching for a baseline: functional imaging and the resting human brain
Nat Rev Neurosci.
2001 Oct.
Abstract
Functional brain imaging in humans has revealed task-specific increases in brain activity that are associated with various mental activities. In the same studies, mysterious, task-independent decreases have also frequently been encountered, especially when the tasks of interest have been compared with a passive state, such as simple fixation or eyes closed. These decreases have raised the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations. We explore this possibility, including the manner in which we might define a baseline and the implications of such a baseline for our understanding of brain function.
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